The integration of genetics into oncology practice is transforming the landscape of cancer care, offering unprecedented opportunities to personalize prevention, diagnosis, and treatment. As our understanding of oncogenetics deepens, innovations in genetic and genomic testing are enabling more accurate identification of inherited cancer predispositions. In parallel, the application of polygenic risk scores is enhancing risk stratification and informing targeted therapies, marking the beginning of a new era of precision medicine.
This Collection aims to highlight cutting-edge research and clinical advancements that bridge the gap between genetic discoveries and their implementation in oncology. We welcome contributions that explore how emerging technologies, clinical studies, and ethical frameworks are shaping the future of cancer care. Special attention is given to the impact of genetics and genomics across the cancer continuum, from risk assessment and prevention to early detection, treatment, and survivorship.
We invite submissions of original research articles, reviews, case studies, and comments on topics including, but not limited to:
• Applications of genetic testing across all cancer types
• Advances in somatic and germline genomic testing, including polygenic risk scores
• The impact of genetics and genomics on cancer prevention, early detection, and treatment
• Use of genetic and genomic tools across the cancer care continuum
• Integration of genetics and genomics in primary, secondary, and tertiary care
• Clinical and implementation studies in oncogenetics
• Development and application of targeted therapies in precision oncology
• Integration of genetic counseling into oncology practice
• Ethical, legal, and social implications of cancer genetics
• The role of cancer registries in improving care for individuals with inherited predispositions
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