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  • RESEARCH BRIEFINGS

Using heat to power up molecular systems

Synthetic DNA circuits and neural networks have previously been developed to process molecular information while consuming energy stored in kinetic traps. Now they have been re-engineered to take in energy from heat when the temperature increases, and to recharge themselves by restoring kinetic traps for subsequent computation.
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This is a summary of: Song, T. & Qian, L. Heat-rechargeable computation in DNA logic circuits and neural networks. Nature 646, 315–322 (2025).

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doi: https://doi.org/10.1038/d41586-025-03241-y

Figure 1 is published under a CC BY-NC-ND 4.0 licence.

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