Focus issue: Ageing and cancer
With articles on modelling cancer in the aged context, stromal senescence & age-induced metabolic reprogramming
With articles on modelling cancer in the aged context, stromal senescence & age-induced metabolic reprogramming
In this Review, Mao et al. discuss the regulation and interplay of the metabolic cell death pathways ferroptosis, disulfidptosis and cuproptosis and explore how these mechanisms can be harnessed for cancer therapies.