Course Course Title L T P C

Code
BIOMEDICAL SIGNAL ANALYSIS 3 0 2 4
BM2003

UNIT I- INTRODUCTION TO BIOMEDICAL SIGNALS (9 hours)

Bioelectric signals-Action potential, Electro-neurogram, Electro-oculogram, Electro-encephalogram,
Evoked potential, Electro-cardiogram, Electrogastrogram, bio-impedance signals, mechanical signals
- bioacoustics signals, biochemical signals- objectives of biomedical signal analysis, difficulties in
biomedical signal analysis.

UNIT II – NEUROLOGICAL SIGNAL PROCESSING (9 hours)

EEG signal and its characteristics, EEG analysis, Linear prediction theory Autoregressive method,
Moving average model, Autoregressive moving average model- Estimation of AR,MA, ARMA
parameters. AR modeling of Seizure EEG, Spectral error measure, Adaptive segmentation

UNIT III –CARDIOLOGICAL SIGNAL PROCESSING (9 hours)

ECG data acquisition and lead system, ECG parameters and their estimation,
Multi-scale analysis for parameters estimation of ECG waveforms, ECG QRS complex detection-
differentiation techniques-Template matching techniques, Arrhythmia analysis monitoring, long term
continuous ECG recording

UNIT IV–ADAPTIVE FILTERS FOR NOISE CANCELLATION IN

BIOSIGNALS (9 hours)
Adaptive filter- principles, steepest descent algorithm, Widrow-Hoff least mean square adaptive
algorithm, Adaptive noise canceller-cancellation of 60Hz interference in ECG- cancelling donor
heart interference in Heart transplant ECG-cancellation of ECG signals from electrical activity of
chest muscles- cancelling of maternal ECG from fetal ECG- cancellation of high frequency noise in
Electro-surgery. Adaptive line enhancement of diastolic heart sound, Applications of adaptive noise
cancelling method to enhance electro gastric measurements.

UNIT V– SIGNAL PATTERN CLASSIFICATION AND DIAGNOSTIC

DECISION (9 hours)
Pattern classification, supervised pattern classification- discriminant and decision functions-distance
functions-nearest neighbour rule, unsupervised pattern classification-cluster seeking methods,
measures of diagnostic accuracy and cost-Receiver operating characteristics-Application: Normal
versus Ectopic ECG beats

REFERENCES

1. D.C.Reddy, “Biomedical Signal Processing: Priniciples and Techniques”, 2nd edition Tata
McGraw-Hill, New Delhi, 2005.
2. N.Vyas, “Biomedical Signal Processing”,First edition, University Science Press, New Delhi
2011.
3. Metin Akay, “Biomedical Signal Processing”, First edition, Academic Presss Inc,1994.
4. Rangaraj.M.Rangayyan, “Biomedical signal processing”, First edition, IEEE press, 2002.
5. Joseph..D.Bronzino, “Biomedical Engineering Handbook”, 3rd edition CRC Press, 2005.

Course Code Course Title L T P C

BM2006 BIOMECHANICS AND FINITE ELEMENT 3 0 2 4
ANALYSIS

UNIT I – KINEMATICS AND KINETICS FOR ANALYZING HUMAN

MOTION AND BONE GROWTH (9 hours)
Forms of motion – Standard reference terminology – Joint movement: Terminology – Qualitative
analysis of human movement–Tools for measuring kinematics quantities – Basic concepts related to
kinetics – Mechanical loads on human body – Effects of loading – Tools for measuring kinetic
quantities – Composition and structure of bone tissue – Bone growth and development – Bone
response to stress – Osteoporosis

UNIT II – BIOMECHANICS OF HUMAN LOWER EXTREMITY AND UPPER

EXTREMITY (9 hours)
Human Upper Extremity (Shoulder, Wrist, and Joints of hand): Structure and movements, loads on
the region, and common injuries;
Human Lower Extremity (Hip, Knee, and Ankle): Structure and movements, loads on the region, and
common injuries;

UNIT III – BIOMECHANICS OF SPINE, LINEAR AND ANGULAR

KINETICS AND KINETMATICS OF HUMAN MOVEMENT (9 hours)
Spine: Structure, movements, muscles, and loads on the region – Common injuries of back and neck
– Newton’s Laws – Mechanical behavior of bodies in contact work – Power, and energy
relationships – Resistance to angular acceleration – Linear kinematic quantities – Acceleration –
Kinematics of projectile motion – Factors influencing projectile trajectory – Analyzing projectile
motion – Angular kinematic relationships – Relationships between linear and angular motion.

UNIT IV – BASICS OF FINITE ELEMENT ANALYSIS (9 hours)

Introduction–Basic equations in Elasticity – Matrix displacement formulation–Element shapes,
nodes, nodal unknowns and coordinate systems–shape functions–strain displacement matrix – Linear
elements – quadratic elements–– analysis of one dimensional problem – rectangular elements –
linear triangular elements – quadratic triangular elements- isoparametric elements – two dimensional
integrals

UNIT V – ANSYS SOFTWARE AND FINITE ELEMENT METHOD

(9 hours)
Introduction – fundamentals of ANSYS, and discretization – modeling operations – solid modeling
– Boolean operators – additional operations – viewing of model – meshing –ANSYS solution and
post processing – case studies in biomechanics.

REFERENCES

1. Susan .J. Hall, “Basic biomechanics”, Tata Mcgraw Hill, Sixth edition, 2011.
2. J. G Webster, “Medical instrumentation –Application & design”, John Wiley and sons Inc.
Fourth edition, 2010.
3. D. J. Schneck and J. D. Bronzino, “Biomechanics- Principles and Applications”, CRC Press,
Second Edition, 2000.
4. Duane Knudson, “Fundamentals of Biomechanics”, Springer, Second Edition, 2007.
5. S.S. Bhavikati, “Finite element analysis”, New Age International Ltd, First edition, 2005.
Course Code Course Title L T P C
BM2113 DESIGN OF MEDICAL DEVICES 3 0 0 3
1
UNIT I - DATA ACQUISITION AND NOISE ISSUES (9 hours)
Physical Principles of Sensing, Sensor Interfacing, Driving Bridges, Signal
Conditioning Amplifiers, Data Acquisition: Sample and Hold Conversion, Multi-channel
Acquisition, Internal Noise In OPAMPS, Bypass Capacitors and Resonances, Electromagnetic
Interference, interference from external electric field, conductive interference, electrical safety and
signal isolation, Overload Protection, Output Filtering¸ Power Failure Warning

UNIT II - DESIGN METHODOLOGIES (9 hours)

EDR design methodologies, PCB assembly, mechanical assembly, product design and modelling,
fabrication and assembly, Multi-layer circuit design, Advanced OrCAD design, Design rule
specifications

UNIT III – DIAGNOSTIC EQUIPMENT DESIGN (9 hours)

ECG, EEG, Blood pressure monitor, Thermometer, System description and diagram of pulse
oximeter, Optical fiber optics for circulatory and respiratory system measurement, Magnetic
resonance imaging (MRI) Hardware design

UNIT IV - THERAPEUTIC EQUIPMENT DESIGN (9 hours)

Pacemaker, External cardio-vector defibrillator, Implantable cardio-vector defibrillator, Deep brain
stimulation, Functional electrical stimulator (FES), Haemodialysis delivery system, Mechanical
ventilator

UNIT V - IMPLANT AND PROSTHESIS DESIGN (9 hours)

Intraocular lens implant, Cochlear implants, Heart valves, Design of artificial pancreas, Drug eluting
stent and its engineering design, synthetic crafts, Total hip prosthesis, Joint replacement

REFERENCES

1. Gail Baura, “Medical Device Technologies: A Systems Based Overview Using Engineering”,
Elsevier science, 2002.
2. Martin Culjat, Rahul Singh, Hua Lee, “Medical Devices: Surgical and Image-Guided
Technologies”, John Wiley & Sons, Reinaldo Perez, “Design of medical electronic device”,
Elsevier science, 2002.
3. Richard C. Fries, “Handbook of Medical Device Design”, Marcel Dekker AG, 2nd edition 2005.
4. Anthony Y.K.Chan, “Biomedical device technology: principles and design”, Charles C
Thomas, 2008.
5. Theodore R. Kucklick, “The Medical Device Ramp-D Handbook”, Taylor &Francis Group
LLC, 3rd edition 2013.
6. David Prutchi, Michael Norris, “Design and Development of Medical Electronic
Instrumentation: A Practical perspective of the design, construction and test of medical
devices”, John Wiley & Sons, 2005.

Course Course Title L T P C

Code
BM2125 ADVANCES IN REHABILITATION ENGINEERING 3 0 0 3
2
UNIT I - INTRODUCTION, BIOMECHANICS OF MOBILITY AND
UNIVERSAL DESIGN (9 hours)
Rehabilitation Engineering and assistive technology: Design, considerations, concepts and
terminologies– Approaches to rehabilitation: Biomechanics of mobility and universal design -Gait
analysis-Biomechanics of wheel chair
Propulsion-Barrier free design- design for people with disabilities

UNIT II – PERSONAL TRANSPORTATION, MANUAL AND

POWERED (9 hours)
Personal transportation - Lift mechanisms –Wheel chair safety, standards, testing. Manual and
powered wheel chairs -Design and components Materials-Wheels and casters-human factors-Power
wheel chair class’s Motor selection-Batteries-Microprocessor and fault tolerant control.

UNIT III – PROSTHETICS, ORTHOTICS AND REHABILAITATION

ROBOTICS (10 hours)
Prosthetics: Introduction, upper, lower and external, internal prosthetics- Orthotics: Functional
electrical stimulation (FES), ambulatory aids, aids for daily living, prosthetics using myo-electric
signal control- Rehabilitation robotics: Introduction, configuration and its components, control and
sensors

UNIT IV - SENSORIAL PROSTHESES (9 hours)

Engineering concepts in sensory rehabilitation engineering-Sensory augmentation and substitution-
Retinal prostheses-Intelligent techniques in
hearing rehabilitation-tactual sensory substitution-artificial larynx

UNIT V - REHABILITATION MEDICINE AND ADVOCACY (8 hours)

Rehabilitation team-Organization of services-Disability assessmentbehavioral disorders-Psychiatric
problems and rehabilitation- Legal aspects and provisions available

REFERENCES

1. Rory.A.Cooper, “Rehabilitation Engineering Applied to Mobility and Manipulation”, First

Edition, CRC Press, 2010.
2. Horia-Nicolai.L.Teodorescu, Lakhmi C. Jain, “Intelligent Systems and Technologies in
Rehabilitation Engineering”, First Edition, CRC press, 2010.
3. Glenn Hedman, “Rehabilitation Technology”, First Edition, Haworth Press Inc, 1990.
4. Michael P. Barnes, Anthony B. Ward, “Oxford Handbook of Rehabilitation Medicine”, First
Edition, Oxford University Press,
2005

DRIVES AND ACTUATORS L T P C

MH2005
Total Contact Hours – 75 3 0 2 4

UNIT- I FLUID POWER SYSTEM GENERATION AND ACTUATORS (9 hours)

3
Need for automation, Classification of drives-hydraulic, pneumatic and electric –comparison – ISO
symbols for their elements, Selection Criteria. Generating Elements- Hydraulic pumps - gears, vane,
piston pumps- selection and specification -Drive characteristics – Utilizing Elements- Linear and
Rotary actuators – Types, mounting details - Hydraulic power packs –accumulators.

UNIT-II CONTROL AND REGULATION ELEMENTS (9 hours)

Control and regulation Elements—Direction, flow and pressure control valves--Methods of
actuation, types, Spool valves-operating characteristics-electro hydraulic proportional and servo
valves-Different types-characteristics and performance

UNIT-III CIRCUIT DESIGN FOR HYDRAULIC AND PNEUMATICS (9 hours)

Circuit Design methods – sequencing circuits design - combinational logic circuit design-cascade
method - Karnaugh map method- Electrical control of pneumatic and hydraulic circuits-use of relays,
timers, counters, Programmable logic control of Hydraulic and Pneumatic circuits, PLC ladder
diagram for various circuits, motion controllers, use of field busses in circuits. Design and analysis
of Hydraulic and Pneumatic system.

UNIT-IV ELECTRICAL ACTUATORS (9 hours)

DC Motor and AC Motor- Types, Working principle, characteristics, Merits and Demerits,
Applications- Stepper motor- principle ,classification, construction. Piezo electric actuators – Linear
actuators and Hybrid actuators – Applications

UNIT-V ELECTRICAL DRIVE CIRCUITS (9 hours)

DC Drives – Speed control of DC drives using converters and chopper, Speed, direction and position
control using H-bridge under PWM mode. Control of AC motor drives – Need for V/ F drives, Rotor
resistance control. Slip power recovery scheme. – Closed loop control of DC and AC drives-
Stepper Motor – Drive circuits for speed and position control, Controllers for BLDC motor,
Switched reluctance motor. .

REFERENCES
1. Antony Esposito, “Fluid Power Systems and Control”, Prentice-Hall, 2006.
2. Peter Rohner, Fluid Power Logic Circuit Design”, The Macmillan Press Ltd., London, 1979.
3. W.Bolton, “Mechatronics, Electronic Control Systems in Mechanical and Electrical
Engineering”, Pearson Education, 2003.
4. Gopal K.Dubey, “Fundamentals of Electrical Drives”, Narosa Publications, 2001.
5. Bhimbra. Dr.P.S., “Power Electronics”, Khanna Publishers, 2012.
6. Singh. M.D and Khanchandani. K.B., “Power Electronics”, Tata McGraw Hill Publishing Co.
Ltd., New Delhi, 2000.