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Misunderstandings between empirical and theoretical scientists

The Poincaré-Lippman gap is an implicit problem in biomedical research when empirical scientists borrow mathematical tools.

Nov 13, 2025 • Manjari Narayan

Most Popular

Biomarker Qualification

Aug 18, 2025 • Manjari Narayan

Sewall Wright and John Tukey on Path Analysis in 1952

Dec 2, 2024 • Manjari Narayan

Intercurrent Events

Jul 30, 2025 • Manjari Narayan

Neurostats Digest #3

Apr 30, 2025 • Manjari Narayan

Digests

Neurostats Digest #6

Blood biomarkers, responders as a causal construct, low vs. high risk use-cases of biomarkers

Nov 21, 2025 • Manjari Narayan

Neurostats Digest #5

Notes round up on theoretical psychiatry, causal inference, and understanding papers

Oct 15, 2025 • Manjari Narayan

Neurostats Digest #4

Methodological reductions, primitive epistemic status of biomarkers

May 31, 2025 • Manjari Narayan

Neurostats Digest #3

Statistical transformations, virtual twins, progress in methodological discovery

Apr 30, 2025 • Manjari Narayan

Neurostats Digest #2

Select links and reading on regulatory science, free energy principle, vitamin-D interventions, preterm birth interventions

Jan 31, 2025 • Manjari Narayan

Surrogate Dispatches

Request for Information: Synthetic Datasets

Share how you validate synthetic data as a proxy for the real data

Nov 14, 2025 • Manjari Narayan

Biomarker Qualification

Qualification is to regulators what validation is to scientists

Aug 18, 2025 • Manjari Narayan

Predictive (in)validity

Translational probabilities of success and selection bias

May 12, 2025 • Manjari Narayan

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