Abstract
Storey et al. reply — These reports assess the frequency of the p53Arg allele in different populations and conclude that homozygous p53Arg is not a risk factor for cancer associated with human papilloma virus (HPV). The functional differences between the p53 isoforms that we have described1,2 provoked our initial epidemiological study. As we concluded then, it is crucial that investigations should be extended to different populations, and we are encouraged that such studies are underway.
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References
Storey, A. et al. Nature 393, 229–234 (1998).
Thomas, M. et al. (in the press).
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Storey, A., Thomas, M., Kalita, A. et al. p53 polymorphism and risk of cervical cancer. Nature 396, 532 (1998). https://doi.org/10.1038/25043
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DOI: https://doi.org/10.1038/25043
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