An electrical biosensor is described that can continuously track morphological changes of adherent cells providing quantitative data from both sparse and confluent cultures. The method is capable of detecting vertical motion of cells of the order of 1 nm, much below the resolution of an optical microscope.
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Giaever, I., Keese, C. A morphological biosensor for mammalian cells. Nature 366, 591–592 (1993). https://doi.org/10.1038/366591a0
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DOI: https://doi.org/10.1038/366591a0
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