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Close look at gene conversion hot spots

Nature Genetics volume 36, pages 114–115 (2004)Cite this article

New work has directly estimated male gene conversion rates in three regions of the human genome and identified gene conversion hot spots in the same locations as previously identified crossover hot spots. This work elucidates the fine-scale structure of linkage disequilibrium (LD) in the human genome and will be useful in association studies and other LD-based applications in population and human genetics.

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Figure 1: Schematic of the possible effects of gene conversion and marker density on patterns of LD.

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  1. Program in Molecular and Computational Biology at The University of Southern California, 1042 W. 36th Place, DRB 289, Los Angeles, 90089, California, USA

    Jeffrey D Wall

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  1. Jeffrey D Wall
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Wall, J. Close look at gene conversion hot spots. Nat Genet 36, 114–115 (2004). https://doi.org/10.1038/ng0204-114

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