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How to store Microbiology Susceptibility data into OMOP CDM #172

@crabcakeworld

Description

@crabcakeworld

CDM or THEMIS convention?

THEMIS

Table or Field level?

Table

Is this a general convention?

Applies to multiple fields

Summary of issues

Below is taken from a real EHR data (PHI removed):

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mio_src mio_body_site cm_organism specimen antibiotic result result_description lab test LOINC code
Abscess Hand, Right Staphylococcus aureus Abscess Moxifloxacin <=0.25 Sensitive 31039-1

How to put these information into OMOP CDM?

Summary of answer

This has not been rectified.

When taking above data into OMOP CDM, it will load into 3 records as follows:

  1. A Specimen record that contains specimen and anatomic site.
  2. A Measurement record that contains microbiology test and test result and point to the first Specimen record.
  3. A Measurement record that contains the organism that is being tested and point to the 2nd Measurement record.

The above source data will become following:

Record 1

<style> </style>
specimen_id specimen_concept_id anatomic_site_concept_id disease_status_concept_id
34567890 34567890 4124271 (Abscess swab) 4302584 (Structure of right hand)

Record 2

<style> </style>
measurement_id measurement_concept_id value_as_Concept_id value_as_number unit_concept_id measurement_source_value measurement_event_id meas_event_field_concept_id
12345678 3037708 (Moxifloxacin [Susceptibility]) 4307105 (Sensitive) 0.25 8859 (microgram per milliliter) 31039-1 (Moxifloxacin [Susceptibility]) 34567890 1147049 (specimen.specimen_id)

Record 3

<style> </style>
measurement_id measurement_concept_id value_as_Concept_id value_as_number unit_concept_id measurement_source_value measurement_event_id meas_event_field_concept_id
23456789 4189544 (Microbial culture) 4149419 (Staphylococcus aureus)       12345678 1147729 (measurement.measurement_id)

Related links

https://forums.ohdsi.org/t/mapping-microbiology-susceptibility-into-omop-cdm4-observations/167/57

Other comments/notes

The above solution has a problem. In the 3rd record, the value_as_concept_id field only allows concept_id of "Meas Value" domain. But the organism concept_id, 4149419 (Staphylococcus aureus) belongs to Observation domain. There might be other solutions out there. But the above solution is the presiding idea.

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