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It should be possible to add another parameter to the differential accessibility script specifying the number of cores in order to parallelize DESeq2:
http://bioconductor.org/packages/devel/bioc/vignettes/DESeq2/inst/doc/DESeq2.html#using-parallelization
Probably also worth adding an option just to skip this step e.g. --skip_differential_analysis
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enhancementNew feature or requestNew feature or request