Tags: cbg-ethz/cojac
Tags
Version 0.9.3
preview feature:
- produce tables that can be used for LolliPop
- tabmut: --add-mutations - add mutations strings to tabmut
Necessary for using "bootstraping" confidence intervals in LolliPop
- coocmutbamscan: --fix-subsets - subset of coocurrating mutations
Fix variants attribution when cooccurrence are subset/superset of other variants:
if var 1 has mutations A, B and C and var 2 has muations A and B
amplicon with mutations A and B is flagged to both var 1 and 2
Version 0.9.1
Bug fixes:
- `--url` was broken in `sig-generate` and `cooc-curate`
New features:
- sort BED file by position, on by default
(avoids wrong amplicons names in out-of-order file)
- comment amplicons query file, on by default
(add comments such as `# SARS-CoV-2_25_RIGHT`)
- helps double check amplicon names
- simplify searching for primers affected by mutation
by (ab)using COJAC's cooc-mutbamscan and primer BED files
Version 0.9 - Converted to a proper python package with poewtry and click - Command format has changed - Integrated into V-pipe - Tool for generating list of mutations from Cov-Spectrum to be used in creating COJAC's specific YAML files - Select API end-point on Cov-Spectrum (ENA or GISAID) - Accesskey for non-open (GISAID) on Cov-Spectrum - Tool for converting list of mutations from TSV on Covariants.org repo - Partial support for aarch64 - pysam still missing on bioconda Publication: - change of literature ref to Nature Microbiology - Notebooks used in publication more portable
Version 0.2 - hard-coded table replaced with: - BED fields for amplicons regions - YAML for signatures / variants definition - amplicon query tables can themselve by saved and reused - tool for importing signatures from PHE-Genomics - (preliminary) tool for evaluating quality of variants definition using mutation prevalences fetched from CoV-Spectum