I have my server set up in Transdroid via a domain name. This domain name is configured in Cloudflare as a CNAME record (resolving the IP address of another domain name) and everything works correctly when I'm connecting from outside of my home network.
On my local network, I attempted to override the CNAME entry for local DNS on my home router (to keep traffic internal) and when I do, Transdroid fails to connect. This CNAME redirect works fine from any browser on my PC.
If I change the local CNAME override to an A record Transdroid works.