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Repository contaning data and codes to reproduce the comparison of sample-wise methods in the rRoma article.

Pathway database

  • GMT file: h.all.v2023.1.Hs.symbols.gmt

Scenario #1: comparison of CF and healthy control samples

  • gene expression data: Rehman_CF_NCF_RNA_exp_matrix_norm.rda

  • samples information : Rehman_CF_NCF_sample_labels.rda

  • rROMA script: rROMA vignette (https://sysbio-curie.github.io/rROMA/index.html)

  • comparison with the other state of the art methods: Rehman_CF_NCF_other_methods.R

Scenario #2: comparison of healthy control samples before and after treatment with IL17+TNFalpha

  • gene expression data: Rehman_IL17_TNFa_RNA_exp_matrix_norm.rda

  • samples information : Rehman_IL17_TNFa_sample_labels.rda

  • exploratory analysis and normalisation of data matrix: Rehman_IL17_TNFa_RNA_exp_matrix_norm.R

  • rROMA script: Rehman_TNF_IL17_rROMA.R

  • comparison with the other state of the art methods: Rehman_TNF_IL17_other_methods.R

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Repository for the comparison of sample-wise methods for the rRoma article

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