Abstract
The appearance of the corpus callosum is one of the most distinct modifications seen in placental mammals and is a diagnostic character just like the placenta itself. It signified a major leap in evolution and its presence maybe linked to the binding mechanisms related to midline fusion and bimanual coordination [1]. Prior to the corpus callosum interhemispheric transfer amongst vertebrates was via the anterior commissure and the hippocampal commissure. It is believed that the corpus callosum originated in placental mammals as a short-cut to reduce interhemispheric transmission times for fibers connecting the motor and sensory areas which otherwise would have to take the longer route through the anterior commissure [2, 3]. In present day placental mammals however only a small contingent of callosal fibers are seen to connect the primary sensory and motor cortices and most callosal fibers are seen to connect higher order centers as has been demonstrated in this study. Callosal axons have been found to terminate in diverse regions of the brain apart from the topographically equivalent areas thus participating in spreading corticocortical synchronous activation to multiple homotropic and heterotopic regions in the hemispheres. This synchronous activity can explain the callosal propagation of an epileptic focus and the effectiveness of a callosotomy to prevent expansion of epileptic activity [1]. This chapter discusses the course and connections of the corpus callosum.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Aboitiz F, Montiel J. One hundred million years of interhemispheric communication: the history of the corpus callosum. Braz J Med Biol Res. 2003;36(4):409–20.
Shah A, Jhawar SS, Goel A. Analysis of the anatomy of the Papez circuit and adjoining limbic system by fiber dissection techniques. J Clin Neurosci. 2012;19(2):289–98.
Shah A, Jhawar S, Goel A, Goel A. Corpus callosum and its connections: a Fiber dissection study. World Neurosurg. 2021 Jul;151:e1024–35.
Shah A, Goel A, Jhawar SS, Patil A, Rangnekar R, Goel A. Neural circuitry: architecture and function-a Fiber dissection study. World Neurosurg. 2019;125:e620–38.
Rhoton AL Jr. The lateral and third ventricles. Neurosurgery. 2002;51(4 Suppl):S207–71.
Peltier J, Verclytte S, Delmaire C, Deramond H, Pruvo JP, Le Gars D, Godefroy O. Microsurgical anatomy of the ventral callosal radiations: new destination, correlations with diffusion tensor imaging fiber-tracking, and clinical relevance. J Neurosurg. 2010;112(3):512–9.
Witelson SF. Hand and sex differences in the isthmus and genu of the human corpus callosum. A postmortem morphological study. Brain. 1989;112(Pt 3):799–835.
Küçükyürük B, Uzan M, Avyasov R, Tahmazoğlu B, İşler C, Sanus GZ, Tanrıöver N. Evaluation of ideal extent of corpus callosotomy based on the location of Intracallosal motor Fibers. World Neurosurg. 2020;144:e568–75.
Van Wagenen WP, Herren RY. Surgical division of commissural pathways in the corpus callosum. Relation to spread of an epileptic attack. Arch Neurol Psychiatr. 1940;44:740–59.
Mazza M, Di Rienzo A, Costagliola C, Roncone R, Casacchia M, Ricci A, Galzio RJ. The interhemispheric transcallosal-transversal approach to the lesions of the anterior and middle third ventricle: surgical validity and neuropsychological evaluation of the outcome. Brain Cogn. 2004;55(3):525–34.
Mirza FA. Commentary: selective posterior callosotomy for treatment of epileptic drop attacks: video documentation of the surgical technique: 2-dimensional operative video. Oper Neurosurg (Hagerstown). 2020;19(5):E516–7.
Paglioli E, Martins WA, Azambuja N, Portuguez M, Frigeri TM, Pinos L, Saute R, Salles C, Hoefel JR, Soder RB, da Costa JC, Hemb M, Theys T, Palmini A. Selective posterior callosotomy for drop attacks: a new approach sparing prefrontal connectivity. Neurology. 2016;87(19):1968–74.
Frigeri T, Paglioli E, Soder RB, Martins WA, Paglioli R, Mattiello R, Paganin R, Palmini A. Control of drop attacks with selective posterior callosotomy: anatomical and prognostic data. Epilepsy Res. 2021;171:106544.
Shah A, Vutha R, Goel A. Radiological Evaluation of Anatomical Extensions of Gliomas Based on White Fiber Tracts: Proposal of a Novel Classification. Neurol India. 2022;70(4):1492–99.
Goel A, Shah A, Dandpat S, Rai S, Prasad A. Gliomas are ‘confined’ to a named white matter tract: a revolution in understanding gliomas. J Craniovert Jun Spine. 2020;11:252–3.
Goel A, Shah A, Vutha R, Dandpat S, Hawaldar A. Is “En Masse” Tumor Resection a Safe Surgical Strategy for Low-Grade Gliomas? Feasibility Report on 74 Patients Treated Over Four Years. Neurol India. 2021;69(2):406–13.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2023 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
About this chapter
Cite this chapter
Shah, A., Parihar, D., Goel, A. (2023). Anatomy of Corpus Callosum and Its Connections and Surgery for Corpus Callosal Tumors. In: Shah, A., Goel, A., Kato, Y. (eds) Functional Anatomy of the Brain: A View from the Surgeon’s Eye. Springer, Singapore. https://doi.org/10.1007/978-981-99-3412-6_17
Download citation
DOI: https://doi.org/10.1007/978-981-99-3412-6_17
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-99-3411-9
Online ISBN: 978-981-99-3412-6
eBook Packages: MedicineMedicine (R0)