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Fig. 5 | Journal of Orthopaedic Surgery and Research

Fig. 5

From: Knockdown of long non-coding RNA LEF1-AS1 attenuates apoptosis and inflammatory injury of microglia cells following spinal cord injury

Fig. 5

LncRNA LEF-AS1 acted as a ceRNA of miR-222-5p to regulate LPS-induced microglia cells apoptosis. a Apoptosis ratio in anti-miR-222-5p and pcDNA-RAMP3 transfected microglia cells. b Western blot assay to measure protein expression of apoptotic markers (Bax, Bcl-2, and cleaved-caspase-3) in microglia cells transfected with anti-miR-222-5p and pcDNA-RAMP3. c Inflammatory cytokines (TNF-α and IL-6) expression levels in microglia cells transfected with anti-miR-222-5p and pcDNA-RAMP3. *P < 0.05

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