Journal
Genome Biology
Genome Biology is a leading open access journal in biology and biomedicine research, with 9.
Genome Biology is calling for submissions to our Collection on epistatic effects.
Epistasis plays a crucial role in shaping the genetic architecture of complex traits. Understanding how gene interactions influence these traits enables more accurate genetic mapping and it enhances our grasp of genetic networks, evolutionary dynamics, and the precision of genomic predictions in personalized medicine. Additionally, research on epistasis informs synthetic biology and genetic engineering by clarifying how gene interactions affect system behavior.
This collection welcomes submissions on:
Genome-wide detection of epistatic interactions
Epistasis in complex diseases
Methodological advancements in epistasis analysis
Integrative approaches for studying gene-gene interactions
All manuscripts submitted to this journal, including those submitted to collections and special issues, are assessed in line with our editorial policies and the journal’s peer review process. Reviewers and editors are required to declare competing interests and can be excluded from the peer review process if a competing interest exists.
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Shefali Setia-Verma
PhD, University of Pennsylvania, USA
Dr Setia-Verma is an Assistant Professor in the Department of Pathology and Laboratory Medicine at the University of Pennsylvania. Her research focuses on linking phenotypes in women's health to genomics, utilizing large-scale, long-term studies to understand the genetic underpinnings of disease predispositions and outcomes. Dr Setia-Verma is particularly intrigued by the field of epistasis, exploring how gene interactions influence health and disease. She aims to revolutionize healthcare by developing models that can diagnose and treat diseases proactively. -
Jianbing Yan
PhD, Huazhong Agricultural University, China
Dr Jianbing Yan is a Professor at Huazhong Agricultural University, China. His research focuses on genomic and genetic studies of maize complex quantitative traits. Dr Yan pays particular attention to the study of epistasis in plants, trying to understand the impact of epistasis on heterosis and complex traits such as yield. His research interest is to use the innovative knowledge and techniques to clone key genes, reveal underlying mechanisms and ultimately enhance the genetic improvement of crops.
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