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Advances in spatial transcriptomics for understanding development and disease

Participating journal: Genome Biology

Genome Biology is calling for submissions on the collection "Advances in Spatial Transcriptomics for Understanding Development and Disease". This collection aims to highlight recent progress in the field of spatial transcriptomics, with a focus on how the emerging technologies are improving our understanding of the cellular processes and molecular mechanisms underlying developmental processes and disease states.

Spatial transcriptomics is a rapidly evolving field that combines high-throughput sequencing with spatial localization information to generate spatially resolved transcriptome maps of tissues and organs. This approach provides a unique opportunity to study gene expression patterns in their native spatial context, allowing for the identification of novel cell types, signaling pathways, and gene regulatory networks involved in organogenesis, tissue differentiation, and disease processes.

The collection will consider articles showcasing the latest findings in spatial transcriptomics, including but not limited to:

Methodological advances and development of novel bioinformatic tools for the analysis of spatial transcriptomics data

Applications of spatial transcriptomics to study the molecular mechanisms underlying normal development and disease states

Integration of spatial transcriptomics data with other omics datasets, such as proteomics, metabolomics, and epigenomics to enable further insights into a wide range of biological processes

We encourage submissions from a wide range of research areas, including developmental biology, cancer biology, immunology, neuroscience, and computational biology. Articles that incorporate multi-omics approaches or use spatial transcriptomics in combination with other imaging modalities are also welcome.

All manuscripts submitted to this journal, including those submitted to collections and special issues, are assessed in line with our editorial policies and the journal’s peer review process. Reviewers and editors are required to declare competing interests and can be excluded from the peer review process if a competing interest exists.

Participating journal

Journal

Genome Biology

Genome Biology is a leading open access journal in biology and biomedicine research, with 9.

Editors

  • Stefania Giacomello

    PhD, SciLifeLab & KTH Royal Institute of Technology, Sweden

    Dr Giacomello is Principal Investigator at SciLifeLab, Sweden, and Associate Professor at KTH Royal Institute of Technology, Sweden. Her research group studies how cell localization influences biological processes across different kingdoms through the use of single-cell and spatial transcriptomics.
  • Johanna Klughammer

    PhD, Gene Center of the Ludwig-Maximilians-University Munich, Germany

    Dr Klughammer is Associate Professor for Systems Immunology in the Department of Biochemistry at the Ludwig-Maximilians-University (LMU), Germany. Her lab specializes in using high-dimensional data including single-cell and spatial transcriptomics to study cellular communities in health and disease with the ultimate goal of better understanding and ultimately fixing pathological conditions.
  • Xiang Zhou

    PhD, University of Michigan, USA

    Dr Zhou is Associate Professor in the Department of Biostatistics in the School of Public Health at University of Michigan, USA. He is also Assistant Director at University of Michigan Precision Health. Before joining UM, he was a Williams H. Kruskal Instructor in the Department of Statistics at the University of Chicago, USA. Dr Zhou's research is primarily focused on developing statistical methods and computational tools for genetic and genomic studies.

Articles

Showing 1-16 of 16 articles