The study of cell biology of infection encompasses the complex interactions between the pathogens and host cells. Beyond its fundamental relevance, understanding the cellular and molecular processes underlying infection is also crucial for developing effective strategies to combat infectious diseases.
Recent technical advances (e.g. super-resolution microscopy and live cell imaging) have allowed researchers to visualize the dynamic interactions between pathogens and host cells in real time, providing insights into processes such as pathogen entry, intracellular survival, and host immune responses. In addition, high-throughput and single-cell omics technologies have enhanced the way we can study host-pathogen interactions and responses during infection.
In support of UN Sustainable Development Goal 3 (SDG 3, Good Health and Well-being), BMC Microbiology presents the collection Cell biology of infection. This Collection highlights research focusing on host-pathogen interactions, mechanisms of cellular response to infection, and the development of host-directed therapies to combat bacterial and viral infections. We invited researchers and experts in the field to submit research articles that explore, but are not limited to, the following topics:
Understanding how pathogens interact with host cells
Mechanisms of viral infection and host response to viral invasion
Host cellular interactions and responses against mycobacterial infections
The impact of infection on normal cellular functions and processes
Host cell metabolism reprogramming in response to viral and bacterial pathogen infections
Host immune response to infection, and mechanisms used by pathogens to evade it
Bacterial adaptation to the host environment and resistance to immune responses
The role of inflammation in the host response to infection and its impact on cellular functions
Membrane fusion, pore formation, membrane disruption, and viral entry
Cellular signaling pathways during infection
Cellular stress responses induced by infection and their impact on host-pathogen interactions
Infection-induced cell death and its role in host defense
Host-directed therapies to combat bacterial and viral infections
Advanced flow cytometry as a tool to study host-pathogen interactions
Multi-omics approaches to investigate host-pathogen interactions and responses during infection
Single-cell RNA sequencing to study host-pathogen interactions
All manuscripts submitted to this journal, including those submitted to collections and special issues, are assessed in line with our editorial policies and the journal’s peer review process. Reviewers and editors are required to declare competing interests and can be excluded from the peer review process if a competing interest exists.