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Molecular Biology of Mutagens and Carcinogens

  • Book
  • © 1983

Overview

Authors:
  1. B. Singer

    1. University of California at Berkeley, Berkeley, USA

  2. D. Grunberger

    1. College of Physicians and Surgeons of Columbia University, New York, USA

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About this book

This book originated in numerous Gordon Research Conferences and many other meetings of scientists working in chemistry, biophysics, biochemistry, and biology related to mutagenesis and carcinogenesis. It seemed the appro­ priate time to sit back and summarize the results of several decades of research in laboratories in different countries. We are very grateful to the Rockefeller Foundation for inviting us to formulate and begin writing the book at the Center for International Studies in Bellagio, Italy, where we were Resident Scholars. We are fortunate to have had the assistance of so many colleagues around the world who cheerfully sent original data, figures, and preprints and lis­ tened patiently to us as we worked out the various conflicting ideas in this fast-moving. field. The names of these scientists are found within the tables, figures, and references. There is one person whose contributions we especially wish to acknowl­ edge. Professor Heinz Fraenkel-Conrat was present at the inception of this book and throughout the writing encouraged and criticized in apprOximately equal proportion. Finally, his editing and amalgamation of our two styles gave us great comfort. B.S. D.G.

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-xii
    Download chapter PDF

  2. Introduction

    • B. Singer, D. Grunberger
    Pages 1-2

  3. Chemicals as Environmental Mutagens and Carcinogens

    • B. Singer, D. Grunberger
    Pages 3-13

  4. Intrinsic Properties of Nucleic Acids

    • B. Singer, D. Grunberger
    Pages 15-44

  5. Reactions of Directly Acting Agents with Nucleic Acids

    • B. Singer, D. Grunberger
    Pages 45-96

  6. Metabolic Activation of Carcinogens and Mutagens

    • B. Singer, D. Grunberger
    Pages 97-141

  7. Reactions of Metabolically Activated Carcinogens with Nucleic Acids

    • B. Singer, D. Grunberger
    Pages 143-197

  8. Conformation of DNA Modified by Bulky Aromatic Carcinogens

    • B. Singer, D. Grunberger
    Pages 199-219

  9. Repair in Mammalian Organs and Cells

    • B. Singer, D. Grunberger
    Pages 221-253

  10. Site-Directed Mutagenesis

    • B. Singer, D. Grunberger
    Pages 255-262

  11. Back Matter

    Pages 263-347
    Download chapter PDF
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Authors and Affiliations

  • University of California at Berkeley, Berkeley, USA

    B. Singer

  • College of Physicians and Surgeons of Columbia University, New York, USA

    D. Grunberger

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Bibliographic Information

  • Book Title: Molecular Biology of Mutagens and Carcinogens

  • Authors: B. Singer, D. Grunberger

  • DOI: https://doi.org/10.1007/978-1-4613-3772-0

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Plenum Press, New York 1983

  • Softcover ISBN: 978-1-4613-3774-4Published: 12 October 2011

  • eBook ISBN: 978-1-4613-3772-0Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XII, 348

  • Topics: Cancer Research, Biochemistry, general, Medical Biochemistry

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