Optimizing genetic ancestry adjustment in DNA methylation studies: a comparative analysis of approaches Kira D. HöfflerSeyma KatrinliStéphanie Le Hellard Methodology Open access 14 October 2025 Article: 69
Proteins driving liquid-liquid phase separation and histone modifications cooperatively associate with chromatin looping and transcriptional regulation Xue JiYumin Nie Research Open access 10 October 2025 Article: 68
Antagonistic histone post-translational modifications improve the fidelity of epigenetic inheritance - a Bayesian perspective B. N. Balakrishna PrabhuAditya Naman SoniNithya Ramakrishnan Research Open access 10 October 2025 Article: 67
Multigenerational temperature effects on paternal epigenetic inheritance in European sea bass Núria Sánchez-BaizánFrançois AllalFrancesc Piferrer Research Open access 08 October 2025 Article: 66
ING5: multifaceted roles beyond tumor suppression in cellular physiology and disease Jie LiaoXiaohuan ZhangYingnan Liao Review Open access 08 October 2025 Article: 65
Protamine expression in somatic cells condenses chromatin and disrupts transcription without altering DNA methylation Deepika PuriAlexandra BottWolfgang Wagner Research Open access 04 October 2025 Article: 64
Disruption of histone acetylation homeostasis reveals multilayered chromatin regulation for transcriptional resiliency Vrinda VenuEric M. SmallChristina R. Steadman Research Open access 03 October 2025 Article: 63
Antibiotics induce overexpression of alpha satellite DNA accompanied with epigenetic changes at alpha satellite arrays as well as genome-wide Sven LjubićMaja MatulićIsidoro Feliciello Research Open access 26 September 2025 Article: 62
Roles of KDM5 demethylases in therapeutic resistance of cancers Xiaobo ChenManjun ChenXudong Yang Review Open access 26 September 2025 Article: 61
Cohesin regulation of genome organization in mature granule neurons in the mouse cerebellum Omar A. Payán ParraZiyu ZhaoYue Yang Research Open access 26 September 2025 Article: 60
Structural DNMT-nucleosome contacts are related to DNA methylation patterns Kevin GeorgeKerstin NeiningerVolkhard Helms Research Open access 12 September 2025 Article: 59
The isoflavone genistein selectively stimulates major satellite repeat transcription in mouse heterochromatin Thomas FuhrmannNicholas ShukeirThomas Jenuwein Research Open access 25 August 2025 Article: 58
Comparison of current methods for genome-wide DNA methylation profiling Ana Regina de AbreuJoe IbrahimKen Op de Beeck Research Open access 25 August 2025 Article: 57
The epigenetic circle: feedback loops in the maintenance of cellular memory Marko TomljanovićCita Hanif MuflihahPawel Mikulski Review Open access 20 August 2025 Article: 56
Direction and modality of transcription changes caused by TAD boundary disruption in Slc29a3/Unc5b locus depends on tissue-specific epigenetic context Paul SalnikovPolina BelokopytovaVeniamin Fishman Research Open access 12 August 2025 Article: 55
Multi-omic integration of single-cell data uncovers methylation profiles of super-enhancers in skeletal muscle stem cells Anyu ZengHailong LiuBaoxi Yu Research Open access 11 August 2025 Article: 54
TET1 functions as a tumor suppressor in lung adenocarcinoma through epigenetic remodeling and immune modulation Abdur RahimBrian L. RuisNatalia Y. Tretyakova Research Open access 11 August 2025 Article: 53
H3K4me3 regulates the transcription of RSPO3 in dermal papilla cells to influence hair follicle morphogenesis and development Zhenyu ZhongKangkang BaiXin Wang Research Open access 08 August 2025 Article: 52
Bromodomain proteins IBD1 and IBD2 link histone acetylation to SWR1- and INO80-mediated H2A.Z regulation in Tetrahymena Jyoti GargAlejandro SaettoneJeffrey Fillingham Research Open access 06 August 2025 Article: 51
Dynamic epigenomic landscape and gene regulatory networks during embryonic development in Pacific white shrimp (Litopenaeus vannamei) as revealed by histone modification profiling using CUT&Tag Jiale ShiZhangru QiZhi Ye Research Open access 04 August 2025 Article: 50
Insulator BEAF32 regulates expression of tissue-specific genes and piRNA source loci in Drosophila ovaries Anastasia A. KobelyatskayaValeria MorgunovaAlla Kalmykova Research Open access 28 July 2025 Article: 49
Histone H4 lysine 20 methylation marks genes dynamically regulated during erythroid maturation Kristin MurphyMichael GetmanLaurie Steiner Research Open access 26 July 2025 Article: 48
Identification of genetic and non-genetic modifiers of genomic imprinting through screening of imprinted DMR methylation in humans Francesco CecereRaissa RelatorAndrea Riccio Research Open access 24 July 2025 Article: 47
H2A.X N-terminal acetylation is a newly identified NAA40-mediated modification that is responsive to UV irradiation Ariel KlavarisCostas KoufarisAntonis Kirmizis Research Open access 16 July 2025 Article: 46
Improved epigenetic age prediction models by combining sex chromosome and autosomal markers Zhong WanPeter HennemanPernette J. Verschure Research Open access 15 July 2025 Article: 45
Epigenetic regulation of MED12: a key contributor to the leukemic chromatin landscape and transcriptional dysregulation Arundhati ChavanCassidy JonesSamrat Roy Choudhury Research Open access 14 July 2025 Article: 44
Introduction of epigenetic variation contribute to resistance against the human parasite Schistosoma mansoni Nelia Luviano-AparicioMarie LopezChristoph Grunau Research Open access 14 July 2025 Article: 43
Correction: Artificial intelligence in cancer epigenomics: a review on advances in pan-cancer detection and precision medicine Karishma SahooPrakash LingasamyVijayachitra Modhukur Correction Open access 11 July 2025 Article: 42
Molecular mechanisms and biological functions of active DNA demethylation in plants Ruixian ZhuYan XueWeiqiang Qian Review Open access 05 July 2025 Article: 41
The multitalented TIP60 chromatin remodeling complex: wearing many hats in epigenetic regulation, cell division and diseases Maria Virginia SantopietroDiego FerreriGiovanni Messina Review Open access 02 July 2025 Article: 40
Detecting Protein-DNA binding in single molecules using antibody guided methylation Apoorva ThatavartyNaor SagyDaniel Z. Bar Methodology Open access 01 July 2025 Article: 39
Bath: a Bayesian approach to analyze epigenetic transitions reveals a dual role of H3K27me3 in chondrogenesis Christoph NeuManuela WuellingAndrea Vortkamp Research Open access 27 June 2025 Article: 38
Functional characterization of transcriptional enhancers in an Anopheles genetic locus controlling natural resistance to the malaria parasite, Plasmodium falciparum Natalia Marta Zmarlak-FeherKathryn S. TaquetMichelle M. Riehle Research Open access 24 June 2025 Article: 37
Cell identity and 5-hydroxymethylcytosine Floris HonigAdele Murrell Review Open access 19 June 2025 Article: 36
Artificial Intelligence in cancer epigenomics: a review on advances in pan-cancer detection and precision medicine Karishma SahooPrakash LingasamyVijayachitra Modhukur Review Open access 14 June 2025 Article: 35
DNA methylation mechanisms in the maturing and ageing oocyte Carla CaniçaisSara VasconcelosC. Joana Marques Review Open access 11 June 2025 Article: 34
Cohesin stabilization at promoters and enhancers by common transcription factors and chromatin regulators Audra F. BryanMegan JusticeJill M. Dowen Research Open access 09 June 2025 Article: 33
The linker histone chaperone Prothymosin α (PTMA) is essential for efficient DNA damage repair and the recruitment of PARP1 Ciara A. McKnightMary E. GraichenDavid T. Brown Research Open access 05 June 2025 Article: 32
Unraveling the cohesin-chromatin interface: identifying protein interactions that modulate chromosome structure and function Natalie L. RittenhouseRiya GohilJill M. Dowen Research Open access 02 June 2025 Article: 31
The WAC-downWAC domain in the yeast ISW2 nucleosome remodeling complex forms a structural module essential for ISW2 function but not cell viability Ashish Kumar SinghSabine Ines GrünertFelix Mueller-Planitz Research Open access 21 May 2025 Article: 30
DNMT3B promotes the progression of pheochromocytoma by mediating the hypermethylation of LRP1B promoter Min SunYanrong MaJiuzhi Li Research Open access 09 May 2025 Article: 29
LSD1 induces H3 K9 demethylation to promote adipogenesis in thyroid-associated ophthalmopathy Yuyan XuJing HuHui Chen Research Open access 08 May 2025 Article: 28
Acetylation modification of AIM2 by KAT2B suppresses the AKT/Wnt/β-catenin signaling pathway activation and inhibits breast cancer progression Yaqiong LiLingcheng WangShengchun Liu Research Open access 02 May 2025 Article: 27
H3K27me3 and the PRC1-H2AK119ub pathway cooperatively maintain heterochromatin and transcriptional silencing after the loss of H3K9 methylation Kei FukudaChikako ShimuraYoichi Shinkai Research Open access 02 May 2025 Article: 26
DNA methylation signatures of severe RSV infection in infants: evidence from non-invasive saliva samples Sara PischeddaAlberto Gómez-CarballaGENDRES Consortium Research Open access 28 April 2025 Article: 25
MSH2 is not required for either maintenance of DNA methylation or repeat contraction at the FMR1 locus in fragile X syndrome or the FXN locus in Friedreich’s ataxia Jessalyn Grant-BierKathryn RuppertDaman Kumari Research Open access 28 April 2025 Article: 24
H3F3A K27M mutations drive a repressive transcriptome by modulating chromatin accessibility independent of H3K27me3 in Diffuse Midline Glioma Suraj BhattaraiFaruck L. HakkimJames P. Robinson Research Open access 26 April 2025 Article: 23
Chromatin remodeling and cancer: the critical influence of the SWI/SNF complex Fengxiang HaoYing ZhangBin Zhao Review Open access 23 April 2025 Article: 22
Human chromatin remodelers regulating HIV-1 transcription: a target for small molecule inhibitors Yuan MaChuan LiSusana Valente Review Open access 16 April 2025 Article: 21
Drosophila architectural proteins M1BP and Opbp cooperatively form the active promoter of a ribosomal protein gene Igor OsadchiyAnastasia UmnovaOksana Maksimenko Research Open access 16 April 2025 Article: 20