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Development and validation of a risk prediction model for co-existing depression in middle-aged and older adults with low back pain Kaixia GaoMeichi YanYuling Wang Research Open access 22 October 2025 Article: 1006
Efficacy of semilunar ganglion radiofrequency thermal coagulation in moderate and severe trigeminal postherpetic neuralgia and its impact on serum IL-1β and IL-6 levels Cong WuYi LvChangyang Zhong Research Open access 21 October 2025 Article: 1005
Inflammatory biomarkers in alcohol use disorder: neutrophil/lymphocyte and monocyte/HDL-C ratios as potential diagnostic indicators Omer AcatOkan Imre Research Open access 21 October 2025 Article: 1004
Unveiling the role of lumbar intervertebral space morphology: a novel classification and its impact on cage migration in lumbar fusion surgery Yang HouLei LiuJiangang Shi Research Open access 21 October 2025 Article: 1003
Neuromotor rehabilitation in Parkinsonian syndromes: outcomes and disability after hip fracture Pietro Giuseppe ScamarciaFerdinando AmbrosiGianluca Concardi Research Open access 21 October 2025 Article: 1002
TIGD6 in gastric cancer: exploring its prognostic value and therapeutic potential through molecular and clinical investigations Quanli HanMuhong DengDongbing Li Research Open access 21 October 2025 Article: 1001
Accuracy and reliability of 3D cephalometric landmark detection with deep learning Boyan LiuChang LiuWei Tang Research Open access 21 October 2025 Article: 1000
Correlation of lung ultrasound score with postoperative pulmonary complications in older adults undergoing thoracoscopic lobectomy: a prospective observational study Dongsheng WangYang ZhangXiaohong Li Research Open access 21 October 2025 Article: 999
Development and validation of a diagnostic prediction model for acute liver injury in sepsis based on serum ferritin level Yuxia TaoJianhao WangJinshuai Lu Research Open access 21 October 2025 Article: 998
Association between the Zhejiang University index and chronic diarrhea: a cross-sectional study Dongzhi HongBin XiHao Wu Research Open access 21 October 2025 Article: 997
Mechanism of DKK3 protecting brain tissues in ischemic stroke by regulating LGI1 expression and activity DongLiang ZhouLei MiaoJianMin Wang Research Open access 21 October 2025 Article: 996
Lumbar plexus combined with sacral plexus nerve block anesthesia in elderly patients undergoing hip surgery Zhongping Cao Review Open access 21 October 2025 Article: 995
Longitudinal changes in estimated glucose disposal rate and risk of cardiovascular disease among adults with cardiovascular–kidney–metabolic syndrome stages 0–3: a nationwide prospective cohort study Xiaoming ZhangRui ZengYunzhi Yang Research Open access 17 October 2025 Article: 994
LncRNA Rmst-driven DNMT3A mRNA stabilization through HuR: implications for neuropathic pain therapy Shaoqing ZhangPeng JiangYuanyan Tu Research Open access 17 October 2025 Article: 993
Efficacy and safety of platelet-rich plasma injections for the treatment of knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials Chengjing WangBowen Yao Review Open access 17 October 2025 Article: 992
Identification of diagnostic biomarkers and mitochondrial metabolic characteristics in sepsis-associated acute kidney injury Yichun XiaYiming QianJian Guo Research Open access 17 October 2025 Article: 991
Burden of environmental heat and cold exposure and its attributable risk factors in 204 countries and territories (1990–2021) Zhongyong XieZhihua HuangWei Du Research Open access 17 October 2025 Article: 990
Adipocytes promoted anoikis resistance of head and neck cancer cells via overexpressed ITGA5 Yurong HeYueyue ShiJugao Fang Research Open access 17 October 2025 Article: 989
Transcriptional activation of MACF1 by NR2F1 drives WNT-mediated focal adhesion and metastasis in lung adenocarcinoma Yi ZhouJing WangXiangyu Su Research Open access 16 October 2025 Article: 988
Prevalence, characteristics, and treatment outcomes of epilepsy in Nigeria: a systematic review and meta-analysis Nicholas AderintoBonaventure UkoakaYewande Abigail Adebayo Review Open access 16 October 2025 Article: 986
Exploring the pathogenesis of steroid-induced osteonecrosis of the femoral head co-regulated by mesenchymal stem cells and pyroptosis-related genes with the use of transcriptome Xiang-Bin RongWei-Wei WangPing Zeng Research Open access 16 October 2025 Article: 985
Decoding the link between ischemic stroke and myocardial infarction: a pathophysiological and clinical perspective Ling ChenSenrong LuoXuxing Liao Review Open access 16 October 2025 Article: 984
Targeting SHP-1 to alleviate testicular inflammation and apoptosis in a Poly(I:C)-induced orchitis model Shimin WangJianing TongQingliang Zheng Research Open access 16 October 2025 Article: 983
Crosstalk between ferroptosis and miRNA in type 2 diabetes mellitus and possible therapeutic targeting Hebatallah M. SaadEsraa A. SalemAbeer E. Elsayed Review Open access 16 October 2025 Article: 982
Development and validation of a dynamic nomogram for predicting in-hospital mortality in acute massive cerebral infarction: a retrospective study in a Chinese population Xuhui LiuXujie WangChunjian Ma Research Open access 16 October 2025 Article: 981
Evaluation of 3-year changes in panoramic radiomorphometric indices and fractal dimension values in primary hyperparathyroidism patients Furkan OzbeyAdem PekinceYasin Yasa Research Open access 16 October 2025 Article: 980
Effects of different reperfusion durations on neuronal mitochondrial ultrastructure following cerebral ischemia in diabetic rats: a transmission electron microscopy study Dan WangGui-Sheng Chen Research Open access 15 October 2025 Article: 979
Predictive model of delayed union of tibial and fibular fractures based on PGC-1α, NOS, and Runx2 Bin WangZhiyuan ShiJinwei Yu Research Open access 15 October 2025 Article: 978
Cardiovascular disease mortality risk among patients with metastatic melanoma before and after the approval of immunotherapy in the United States: a Surveillance, Epidemiology, and End Results database-based study Xiaoqin LuoJiaying NiuSijin Li Research Open access 15 October 2025 Article: 977
Associations of carotid flow velocity with cerebral perfusion and cerebral small vessel disease: a community-based prospective study Peipei YangXiaoshuai LiXian-Quan Shi Research Open access 15 October 2025 Article: 976
Epigenetic regulation by WTAPP1 promotes trophoblast dysfunction in gestational diabetes via CNR1/NF-κB activation Na YangYuan LiWeiling Li Research Open access 15 October 2025 Article: 975
Predictors, trends and outcomes associated with urinary tract infections in intracerebral hemorrhage: insights from a National Inpatient Sample Study (2010–2022) Binbin TianChunbo ChenQiongru Yuan Research Open access 15 October 2025 Article: 974
The role of SPRED1 mutation in melanoma Hui HouJiao LiRuixia Hou Review Open access 15 October 2025 Article: 973
Assessing the association between multiple indicators of inflammation and sleep disorders in young and middle-aged women: insights from traditional and machine learning approaches Yi TangKangrui ZhangJuncang Wu Research Open access 15 October 2025 Article: 972
Gut microbiota and metabolism in systemic lupus erythematosus: from dysbiosis to targeted interventions Jing-he ZhuLi-pei WuJian-xiu Yu Review Open access 14 October 2025 Article: 971
How accurate is preoperative MRI in assessing scaphoid vascularity in patients with scaphoid nonunion? A systematic review and meta-analysis Omid Mahmoudi NasabFarid Najd MazharRoshanak Shams Review Open access 14 October 2025 Article: 970
The crosstalk between MicroRNAs and sirtuins: a bit unexpected therapeutic target for cardiovascular diseases Radin KamvarAmir Hossein BarjastehMohammad Hossein Pourhanifeh Review Open access 14 October 2025 Article: 969
Mapping the brain networks underlying creativity enhancement via aesthetic experience Chao HuoChenzhi LiKe Ding Review Open access 14 October 2025 Article: 968
The Sirt3–CD38 axis induces mitochondrial dysfunction in hypertrophied heart by regulating mitochondrial calcium overload Jia LiuNing LiuBin Liu Research Open access 14 October 2025 Article: 967
Treatment options for young patients with asymptomatic severe aortic stenosis: a multicenter retrospective cohort study Yu MaoYang LiuJian Yang Research Open access 14 October 2025 Article: 966
Identification of biomarkers related to neutrophil extracellular traps and potential therapeutic drugs for rheumatoid arthritis using computational analysis Liyong ShengXingliang LiuXiaoqi Gong Research Open access 14 October 2025 Article: 965
Identification of lipid metabolism-related signature in nonalcoholic fatty liver: evidences from transcriptomics and single cell RNA-sequencing analysis Yanqing SunMinjie HuWei Wang Research Open access 13 October 2025 Article: 964
Unraveling the causality between carpal tunnel syndrome and trigger finger through genetic instrumental variables Junming HuangKui DengMingxing Chen Research Open access 13 October 2025 Article: 963