Autophagy

Latest research

1. Dendrobine ameliorates mitophagy-mediated endothelial senescence in diabetic kidney disease through activating the SIRT1/FOXO3a pathway

   • Yan Zhang
   • Xuan Qi
   • Yu-Sheng Shi

   in Chinese Medicine

   Article Open access 18 October 2025

   

2. Suppression of OTUD4 protects against myocardial ischemia-reperfusion injury by increasing autophagic flux and inhibiting apoptosis in cardiomyocytes

   • Xin-xin Sun
   • Lin Qi
   • Yu Zhuang

   in Journal of Molecular Medicine

   Article 18 October 2025

   

3. The crosstalk between MiRNAs and autophagy in leukemia: mechanisms and therapeutic insights

   • Alireza Faghiri Beyrami
   • Ali Akbar Movasaghpour Akbari
   • Mehdi Yousefi

   in Discover Oncology

   Article Open access 17 October 2025

   

4. Chelerythrine inhibits esophageal squamous cell carcinoma progression via PINK1-Parkin-mediated mitophagy

   • Yijian Zhou
   • Zhuo Wang
   • Kuancan Liu

   in Journal of Translational Medicine

   Article Open access 17 October 2025

   

5. Inhibition of Autophagy by ATG5 siRNA Transfection Enhances Anti-cancer Effects of Gum Arabic, Promotes Oxidative Stress-Mediated Apoptosis and Affects DNA Damage and Mitochondrial Membrane Potential in Ovarian Cancer Cells

   • Gulsah Evyapan
   • Berna Ozdem

   in Bratislava Medical Journal

   Article 17 October 2025

   

6. CPT2 inhibition enhances selective autophagy and proliferation in colorectal cancer via GPAT4-dependent glycerophospholipid biosynthesis

   • Kuo Li
   • Hongyan Wang
   • Juan Li

   in Communications Biology

   Article Open access 17 October 2025

   

7. Targeting autophagy to enhance cancer immunotherapy: emerging mechanisms and strategies

   • Jawza A. Almutairi

   in Medical Oncology

   Article 17 October 2025

   

8. Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling

   • Klara Piletic
   • Amir H. Kayvanjoo
   • Anna Katharina Simon

   in Nature Communications

   Article Open access 17 October 2025

   

9. Genkwanin alleviates paraquat-induced acute lung injury by activating SIRT1-mediated Nrf2/HO-1 signaling pathway

   • Shuzhen Liu
   • Lei He
   • Wenhua Qin

   in Naunyn-Schmiedeberg's Archives of Pharmacology

   Article 17 October 2025

   

10. The elongator protein PlElp3b is involved in mycelial growth, autophagy, and virulence of Phytophthora litchii

    • Linlin Ye
    • Jiarui Xing
    • Chengdong Yang

    in Phytopathology Research

    Article Open access 16 October 2025

    

11. A small molecule targets LIC1 to suppress lung tumor growth by inducing autophagy

    • Jia-Luo Huang
    • Lei-Ming Wu
    • Sheng Yin

    in Nature Chemical Biology

    Article 16 October 2025

    

12. PRRSV NSP5 orchestrates dual immune disruption by targeting NLRP3 and STING

    • Xiangyu Huang
    • Xuyan Xiang
    • Xin Li

    in Veterinary Research

    Article Open access 16 October 2025

    

13. Co-treatment Strategy Supports Neuroprotection by Intersecting p62-Keap1-NRF2 and Autophagy Signaling Pathways in the Cellular Model of Parkinson's Disease

    • Oliwia Koszła
    • Przemysław Sołek
    • Krzysztof Jóźwiak

    in Cellular and Molecular Neurobiology

    Article Open access 16 October 2025

    

14. A novel ligustrazine-based nanodelivery system protects against doxorubicin-induced cardiotoxicity by targeting the SIRT5–DUSP1 axis for mitochondrial repair

    • Hongshuo Shi
    • Boxian Pang
    • Xing Chang

    in Journal of Nanobiotechnology

    Article Open access 15 October 2025

    

15. PSME3 drives Tregs infiltration and anti-PD1 resistance in hepatocellular carcinoma by regulating FBXL7/PTEN-mediated metabolic reprogramming

    • Qiuyang Chen
    • Yuan Liang
    • Jian Gu

    in Oncogene

    Article 15 October 2025

    

16. Does autophagy play a key role in the protective effect of oleic acid against oxidative stress in endothelial cells?

    • Ana García-Aguilar
    • Olga Palomino
    • Luis Goya

    in Molecular and Cellular Biochemistry

    Article Open access 15 October 2025

    

17. Mechanisms of high-glucose-induced mitochondrial damage and glycolipid accumulation in largemouth bass

    • Zhihong Liao
    • Xuanshu He
    • Jin Niu

    in Journal of Animal Science and Biotechnology

    Article Open access 15 October 2025

    

18. Genetic and proteomic analysis identifies BAG3 as an amyloid-responsive regulator of neuronal proteostasis

    • Zachary M. Augur
    • Garrett M. Fogo
    • Tracy L. Young-Pearse

    in Acta Neuropathologica

    Article Open access 14 October 2025

    

19. USP8 modulates primary ovarian insufficiency through regulation of Beclin1-dependent autophagy-induced ferroptosis

    • Yun Zhu
    • Haizhen Zhang
    • Awei Zhang

    in Scientific Reports

    Article Open access 14 October 2025

    

20. Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome

    • Rabia R. Khawaja
    • Ernesto Griego
    • Ana Maria Cuervo

    in Nature Cell Biology

    Article 14 October 2025

    

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