Calcium Channels

Latest research

1. Recessive variants in CACNB1: a new culprit in congenital myopathy. Expanding the genetic causes of excitation–contraction coupling disorders

   • Enrico Bertini

   in European Journal of Human Genetics

   Article 16 October 2025

2. TRPM2: a pivotal player in tumor progression and a promising therapeutic target

   • Zhigang Chen
   • Zhengheng Wu
   • Dongmei Wang

   in Cancer Cell International

   Article Open access 15 October 2025

   

3. Role of ANO1 Ca²⁺-activated Cl⁻ channels in the generation of propagating spontaneous Ca²⁺ transients of mouse bladder suburothelial pericytes

   • Ayu Sugiura
   • Retsu Mitsui
   • Hikaru Hashitani

   in Pflügers Archiv - European Journal of Physiology

   Article 13 October 2025

   

4. Deletion of the Voltage-Gated Calcium Channel Gene, Ca_V1.3, Reduces Purkinje Cell Dendritic Complexity Without Altering Cerebellar-Mediated Eyeblink Conditioning

   • Annette Klomp
   • Martha Pace
   • Aislinn Williams

   in The Cerebellum

   Article Open access 11 October 2025

   

5. P2RX4 promotes hepatocellular carcinoma progression via calcium-mediated PI3K/AKT activation and immune remodeling

   • Jianrong Wang
   • Yanmei Gu
   • Yumin Li

   in World Journal of Surgical Oncology

   Article Open access 09 October 2025

   

6. Transcriptional analysis reveals a markedly reduced expression of the voltage-dependent calcium channel α2δ1 subunit in canine prostate cancer compared to benign prostatic hyperplasia

   • Maciej Zacharski
   • Maciej Ugorski
   • Alicja Tomaszek

   in BMC Veterinary Research

   Article Open access 09 October 2025

   

7. Hochauflösende Mikroskopie an spannungsgesteuerten Kalziumkanälen

   • Claudia Steinem

   in BIOspektrum

   Article Open access 08 October 2025

8. Altered venous flow drives endothelial to mesenchymal transition in varicose veins by suppressing PIEZO1-KLF2 signaling

   • S. Ahalya
   • C. L. Karthika
   • S. Sumi

   in Cellular and Molecular Life Sciences

   Article Open access 07 October 2025

   

9. Optogenetic induction of subcellular Ca²⁺ events in megakaryocytes and platelets using a highly Ca²⁺-conductive channelrhodopsin

   • Yujing Zhang
   • Jing Yu-Strzelczyk
   • Markus Bender

   in Communications Biology

   Article Open access 07 October 2025

   

10. TRPV6 channel function is involved in endometrial epithelial cell Ca²⁺ signaling and female mouse fecundity

    • Adela Sota
    • Andreas Beck
    • Petra Weissgerber

    in Cellular and Molecular Life Sciences

    Article Open access 07 October 2025

    

11. A conserved mechanism of LRRC8 channel inhibition by two structurally distinct drugs

    • Toshiki Yamada
    • Paola Bisignano
    • Jerod S. Denton

    in Communications Biology

    Article Open access 06 October 2025

    

12. PIEZO1: a mechanosensitive ion channel in the pathogenesis and pharmacotherapy of diabetic neuropathy

    • Tanya Gupta
    • Thakur Gurjeet Singh
    • Randhir Singh

    in Molecular Biology Reports

    Article 06 October 2025

    

13. Investigation of the heterogeneity of cancer cells using single cell Ca²⁺ profiling

    • Amélie E. Bura
    • Camille Caussette
    • David Crottès

    in Cell Communication and Signaling

    Article Open access 02 October 2025

    

14. Calmodulin binding is required for calcium mediated TRPA1 desensitization

    • Justin H. Sanders
    • Camila Garcia
    • Candice E. Paulsen

    in Nature Communications

    Article Open access 30 September 2025

    

15. N-terminal truncating variants in CACNB1 cause a new congenital muscular disorder

    • Asier Iturrate
    • Nurit Assia Batzir
    • Victor L. Ruiz-Perez

    in European Journal of Human Genetics

    Article Open access 29 September 2025

    

16. Spontaneous calcium transients in hair cell stereocilia

    • Saman Hussain
    • Miloslav Sedlacek
    • Bechara Kachar

    in Scientific Reports

    Article Open access 29 September 2025

    

17. Cadmium Uptake into Rat Osteoblast UMR-106 Cells is Mediated via Multiple Pathways

    • Hitomi Fujishiro
    • Yohei Ikeue
    • Daigo Sumi

    in Biological Trace Element Research

    Article 28 September 2025

    

18. A Pharmacological Perspective on Targeting the Voltage-Gated Calcium Channel Subunit α₂δ_(1–2) to Mitigate Traumatic Brain Injury Sequelae

    • Jijo Stebin Justus
    • Marcelo S. Rodolphi
    • Luis V. Portela

    in Neurochemical Research

    Article 27 September 2025

    

19. The Active Astrocyte: Calcium Dynamics, Circuit Modulation, and Targets for Intervention

    • Dmitri A. Rusakov
    • Thomas P. Jensen
    • Olga Tyurikova

    in Neurochemical Research

    Article Open access 27 September 2025

20. Biophysical and structural insights into the SCN4A E452K variant linked to myotonia and paramyotonia congenita

    • Quentin Plumereau
    • Spencer Lile
    • Mohamed Chahine

    in Scientific Reports

    Article Open access 26 September 2025

    

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