Mechanism of Action

Latest research

1. Vitamin E reduces vasospasm in a rat subarachnoid hemorrhage model

   • Cumaali Demirtas
   • Eyüp Çetin
   • Mehmet Yildirim

   in Neurosurgical Review

   Article 18 October 2025

   

2. The extract of dendrobium Coelonin inhibits PIH induced by AFR CO₂ fractional laser combined with UV-B

   • Die Li
   • Ting Wang
   • Lechun Lyu

   in Photochemical & Photobiological Sciences

   Article 18 October 2025

   

3. Oxymatrine possibly inhibits differentiation and maturation of oligodendrocytes in the remyelination of the toxin-induced demyelination animal model

   • Mei Li
   • Fei Huang
   • Peng Wang

   in Metabolic Brain Disease

   Article Open access 18 October 2025

   

4. In Vitro and In Silico Evaluation of Turmeric Extracts for Anticholinesterase Effects and their Topical Formulation for Future Application in Alzheimer’s Disease

   • Sirirat Srirat
   • Tussavee Jongnui
   • Netnapa Chana

   in Journal of Pharmaceutical Innovation

   Article 18 October 2025

   

5. Tribute to Alberto J. Kaumann

   • Torsten Christ
   • Ursula Ravens

   in Naunyn-Schmiedeberg's Archives of Pharmacology

   Article Open access 18 October 2025

   

6. Assessment of Intramuscular Verapamil as Pharmacological Countermeasure in a Rat Model of Organophosphate DFP-induced Status Epilepticus

   • Yam Nath Paudel
   • Robert E. Blair
   • Laxmikant S. Deshpande

   in Neurotoxicity Research

   Article Open access 18 October 2025

   

7. Theranekron D6 Shows Selective Effects on HEL299, A549, and Hep3B cells, Indicating Potential in the Fight Against Cancer

   • Deniz ŞUMNULU

   in Cell Biochemistry and Biophysics

   Article 17 October 2025

   

8. Neurotherapeutic effects of Vutiglabridin as a Paraoxonase-2 modulator in preclinical models of Parkinson’s disease

   • Heeyoung An
   • Sora Kang
   • Youngmi Kim Pak

   in Molecular Neurodegeneration

   Article Open access 17 October 2025

   

9. Targeting the NLRP3 inflammasome with natural products for ischemia–reperfusion injury across organs: mechanisms, structure–activity relationships, and delivery innovations

   • Rajnish Kumar
   • Archna Singh
   • Mohd. Mustaqeem Abdullah

   in Inflammopharmacology

   Article 17 October 2025

   

10. Chelerythrine inhibits esophageal squamous cell carcinoma progression via PINK1-Parkin-mediated mitophagy

    • Yijian Zhou
    • Zhuo Wang
    • Kuancan Liu

    in Journal of Translational Medicine

    Article Open access 17 October 2025

    

11. Anti-dengue activity of a cellular lipid uptake inhibitor, lipofermata

    • Songkran Thongon
    • Chompunuch Boonarkart
    • Prasert Auewarakul

    in Scientific Reports

    Article Open access 17 October 2025

    

12. Chitosan-Coated Nanoemulsions for pH-Triggered Curcumin Release: Formulation Stability, Kinetic Behavior, and Anticancer Activity Against MCF-7 Cells

    • Winda Trisna Wulandari
    • Mia Ledyastuti
    • I Made Arcana

    in Journal of Pharmaceutical Innovation

    Article 17 October 2025

    

13. Assessment of antiemetic potential of schaftoside through modulation of dopaminergic, serotonergic and muscarinic signaling pathways: in vivo and in silico investigations

    • Md. Shakil Ahmmed
    • Rakib Hossan
    • Muhammad Torequl Islam

    in Naunyn-Schmiedeberg's Archives of Pharmacology

    Article 17 October 2025

    

14. Reactivating intracellular bacterial persisters to boost antibiotic effectiveness

    in Nature Microbiology

    Article 17 October 2025

    

15. Engineering a macromolecular JAK inhibitor for treating acute inflammation and endotoxaemia

    • Min Zhou
    • Yan Wang
    • Jianxiang Zhang

    in Nature Biomedical Engineering

    Article 17 October 2025

    

16. Effects of MS-222 on the physiological and biochemical response, histomorphology, gut microbiota, and flesh quality in largemouth bass (Micropterus salmoides)

    • Ping Gao
    • Rimeng Chen
    • Xuezhen Zhang

    in Fish Physiology and Biochemistry

    Article 17 October 2025

    

17. Drug repurposing in oncology: a systematic review of anticancer effects of Lanatoside C at the molecular level

    • Oluwatobi O. Olayode
    • Tolulope J. Oladosu
    • Blessing T. Ogunoye

    in BMC Cancer

    Article Open access 17 October 2025

    

18. Inhibitory effect of [6]-shogaol against 3CLpro activity and SARS-CoV-2 infection

    • Takashi Tanikawa
    • Tsuyoshi Hayashi
    • Masashi Kitamura

    in BMC Complementary Medicine and Therapies

    Article Open access 17 October 2025

    

19. Pyrroloquinoline quinone targets senescent osteoclasts and reduces spinal pain and endplate degeneration in a lumbar spine instability mouse model

    • Qinghe Geng
    • Yan Geng
    • Jie Li

    in Journal of Translational Medicine

    Article Open access 17 October 2025

    

20. Integrated network pharmacology, docking, MD simulations, and post-MD energy calculation revealed the nootropic effect of Toddalia asiatica

    • Asma Begum
    • Sathiya Ramu
    • Bincy Raj

    in In Silico Pharmacology

    Article 17 October 2025

    

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