Protein vaccines

Latest research

1. Reverse vaccinology-driven construction and bioinformatics validation of a multi-epitope vaccine against Brucella spp.

   • Zheng-Long Chai
   • Xin-Xin Qi
   • Feng-Bo Zhang

   in Scientific Reports

   Article Open access 21 October 2025

   

2. Condensate nanovaccine adjuvants augment CD8⁺ T-Cell-dependent antitumor immunity through mtDNA leakage-triggered cGAS-STING axis activation

   • Yu Tang
   • Zhiyuan Luo
   • Pengfei Zhang

   in Signal Transduction and Targeted Therapy

   Article Open access 21 October 2025

   

3. RNA replicon vaccination confers long-lasting protection against H5N1 avian influenza in 23 zoo bird species

   • Marion Stettler
   • Stefan Hoby
   • Gert Zimmer

   in Nature Communications

   Article Open access 20 October 2025

   

4. Leveraging immunoinformatic for the rational design of highly immunogenic multi-epitope subunit vaccines against Dugbe virus: a molecular docking and simulation approach

   • Ali khan
   • Safir Ullah Khan
   • Muhammad Suleman

   in In Silico Pharmacology

   Article 18 October 2025

   

5. Physicians’ knowledge of, and willingness to encourage caregivers to partake in the RTS S/AS01 and R21 matrix M malaria vaccines roll out – a national survey in Nigeria

   • Mary Aigbiremo Oboh
   • Olumide Thomas Adeleke
   • Titilope Abisola Awotunde

   in BMC Infectious Diseases

   Article Open access 17 October 2025

   

6. Designing a novel mRNA vaccine against foot-and-mouth disease using immunoinformatics approach

   • Samarendra Das
   • Manaswini Jagadeb
   • Jitendra Kumar Biswal

   in In Silico Pharmacology

   Article 17 October 2025

   

7. A replicating RNA vaccine protects against severe fever with thrombocytopenia syndrome virus infection in mice

   • Allie Stamper
   • Thomas Bisom
   • David W. Hawman

   in npj Vaccines

   Article Open access 16 October 2025

   

8. Enhanced immunogenicity in mouse by recombinant BCG prime and protein boost based on latency antigen Rv1733c and/or reactivation antigen RpfE

   • Mitra Ashayeripanah
   • Bahram Kazemi
   • Fereshteh Eftekhar

   in BMC Infectious Diseases

   Article Open access 16 October 2025

   

9. New bird flu vaccine could tackle multiple variants with one shot

   • Benjamin Thompson
   • Shamini Bundell

   in Nature

   Article 15 October 2025

   

10. POST introduction evaluation (PIE) of the malaria vaccine introduced in three pilot countries (Ghana, Kenya, and Malawi) in 2021

    • Jenny A. Walldorf
    • Gillian F. Mayers
    • Rafiq N. A. Okine

    in Malaria Journal

    Article Open access 14 October 2025

    

11. An integrated structural and immunoinformatic approach to design a multi-epitope based vaccine against the foot-and-mouth disease virus

    • Sthitaprajna Sahoo
    • Hak-Kyo Lee
    • Donghyun Shin

    in Scientific Reports

    Article Open access 14 October 2025

    

12. A Transition from Animal- to Plant-Based Proteins to Foster Sustainable Food Systems: Advancements on Diverse Sources, Health-Promoting Properties and Applications as Alternatives/Analogues of Animal-Based Proteins

    • Brij Pal Singh
    • Feyisola Fisayo Ajayi
    • Sajid Maqsood

    in Food and Bioprocess Technology

    Article 10 October 2025

    

13. Identification of a novel B-cell epitope on the spike protein of porcine epidemic diarrhea virus

    • Zhenchui Wu
    • Qiongqiong Zhou
    • Hanchun Yang

    in Animal Diseases

    Article Open access 09 October 2025

    

14. Costs, delivery strategies and implementation challenges for malaria vaccines: a rapid review of literature

    • AbdulMuminu Isah
    • Chinelo Obi
    • Obinna Onwujekwe

    in Tropical Diseases, Travel Medicine and Vaccines

    Article Open access 07 October 2025

    

15. citrOgen: a synthesis-free polysaccharide and protein antigen-presentation to antibody-induction platform

    • Joshua L. C. Wong
    • Julia Sanchez-Garrido
    • Gad Frankel

    in Nature Communications

    Article Open access 06 October 2025

    

16. A BCG-boosting subunit vaccine RS2/DMI induces Th1-polarized immunity by targeting RD6 and secretory antigens of Mycobacterium tuberculosis

    • Xiaochun Wang
    • Qiangsen Zhong
    • Xinkuang Liu

    in Archives of Microbiology

    Article 06 October 2025

    

17. Single dose of foot-and-mouth disease peptide vaccine fully protects swine and achieves intraserotype crossed neutralization

    • Esther Blanco
    • Elisa Torres
    • Sira Defaus

    in npj Vaccines

    Article Open access 06 October 2025

    

18. In silico design and assessment of a multiepitope and multiantigen potential vaccine candidate against Leishmania donovani

    • Satabdi Saha
    • Sahina Laskar
    • Diwakar Kumar

    in In Silico Pharmacology

    Article 03 October 2025

    

19. GRP-based vaccines as a novel approach in cancer immunotherapy: mechanisms, challenges, and prospects

    • Razieh Malekian Shahreza
    • Hamed Zare
    • Hamid Bakherad

    in Cancer Cell International

    Article Open access 03 October 2025

    

20. A safe, T cell-inducing heterologous vaccine against elephant endotheliotropic herpesvirus in a proof-of-concept study

    • Tanja Maehr
    • Javier Lopez
    • Falko Steinbach

    in Nature Communications

    Article Open access 03 October 2025