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Origins of Lymphocyte Diversity vol. 41, 1977

Table of Contents

  • Symposium Participants

    Cold Spring Harb Symp Quant Biol 1977 41: v-xi; doi:10.1101/SQB.1977.041.01.001

Introduction

  • Foreword

    • J. D. Watson
    Cold Spring Harb Symp Quant Biol 1977 41: xv-xvi; doi:10.1101/SQB.1977.041.01.002

  • The Common Sense of Immunology

    • N. K. Jerne
    Cold Spring Harb Symp Quant Biol 1977 41: 1-4; doi:10.1101/SQB.1977.041.01.003

LYMPHOCYTE FUNCTION

T-cell Markers and Differentiation

  • Thymopoietin and Bursopoietin: Induction Signals Regulating Early Lymphocyte Differentiation

    • G. Goldstein,
    • M. Scheid,
    • E. A. Boyse,
    • A. Brand,
    • and D. G. Gilmour
    Cold Spring Harb Symp Quant Biol 1977 41: 5-8; doi:10.1101/SQB.1977.041.01.004

  • Normal and Neoplastic Maturation of T-lineage Lymphocytes

    • I. L. Weissman,
    • S. Baird,
    • R. L. Gardner,
    • V. E. Papaioannou,
    • and W. Raschke
    Cold Spring Harb Symp Quant Biol 1977 41: 9-21; doi:10.1101/SQB.1977.041.01.005

  • Regulation of Cellular and Humoral Immune Responses by T-cell Subclasses

    • H. Cantor and
    • E. A. Boyse
    Cold Spring Harb Symp Quant Biol 1977 41: 23-32; doi:10.1101/SQB.1977.041.01.006

  • Surface Markers and Functional Relationships of Cells Involved in Murine B-lymphocyte Differentiation

    • L. A. Herzenberg,
    • L. A. Herzenberg,
    • S. J. Black,
    • M. R. Loken,
    • K. Okumura,
    • W. van der Loo,
    • B. A. Osborne,
    • D. Hewgill,
    • J. W. Goding,
    • G. Gutman,
    • and N. L. Warner
    Cold Spring Harb Symp Quant Biol 1977 41: 33-45; doi:10.1101/SQB.1977.041.01.007

  • An Unusual Kappa Immunoglobulin Antigen Present on the Membrane of T and B Lymphocytes

    • A. B. Gottlieb,
    • M. Engelhard,
    • H. G. Kunkel,
    • and S. M. Fu
    Cold Spring Harb Symp Quant Biol 1977 41: 47-50; doi:10.1101/SQB.1977.041.01.008

  • Rat Thy-1 Antigens from Thymus and Brain: Their Tissue Distribution, Purification, and Chemical Composition

    • A. F. Williams,
    • A. N. Barclay,
    • M. Letarte-Muirhead,
    • and R. J. Morris
    Cold Spring Harb Symp Quant Biol 1977 41: 51-61; doi:10.1101/SQB.1977.041.01.009

  • Specialized DNA Polymerases in Lymphoid Cells

    • D. Baltimore,
    • A. E. Silverstone,
    • P. C. Kung,
    • T. A. Harrison,
    • and R. P. McCaffrey
    Cold Spring Harb Symp Quant Biol 1977 41: 63-72; doi:10.1101/SQB.1977.041.01.010

  • Studies on the Interactions between Viruses and Lymphocytes

    • B. R. Bloom,
    • A. Senik,
    • G. Stoner,
    • G. Ju,
    • M. Nowakowski,
    • S. Kano,
    • and L. Jimenez
    Cold Spring Harb Symp Quant Biol 1977 41: 73-83; doi:10.1101/SQB.1977.041.01.011

Helper and Suppressor T Cells and Their Products

  • The Hermaphrocyte: A Suppressor-Helper T Cell

    • R. K. Gershon,
    • D. D. Eardley,
    • K. F. Naidorf,
    • and W. Ptak
    Cold Spring Harb Symp Quant Biol 1977 41: 85-91; doi:10.1101/SQB.1977.041.01.012

  • Suppressor T Cells in Tolerance to Non-self and Self Antigens

    • A. Basten,
    • R. Loblay,
    • E. Chia,
    • R. Callard,
    • and H. Pritchard-Briscoe
    Cold Spring Harb Symp Quant Biol 1977 41: 93-103; doi:10.1101/SQB.1977.041.01.013

  • Tolerance: Two Pathways of Negative Immunoregulation in Contact Sensitivity to DNFB

    • H. N. Claman,
    • S. D. Miller,
    • and J. W. Moorhead
    Cold Spring Harb Symp Quant Biol 1977 41: 105-111; doi:10.1101/SQB.1977.041.01.014

  • Current Concepts of the Antibody Response: Heterogeneity of Lymphoid Cells, Interactions, and Factors

    • M. Feldmann,
    • P. Beverley,
    • P. Erb,
    • S. Howie,
    • S. Kontiainen,
    • A. Maoz,
    • M. Mathies,
    • I. McKenzie,
    • and J. Woody
    Cold Spring Harb Symp Quant Biol 1977 41: 113-118; doi:10.1101/SQB.1977.041.01.015

  • Suppressive and Enhancing T-cell Factors as I-region Gene Products: Properties and the Subregion Assignment

    • T. Tada,
    • M. Taniguchi,
    • and C. S. David
    Cold Spring Harb Symp Quant Biol 1977 41: 119-127; doi:10.1101/SQB.1977.041.01.016

B-cell Differentiation and Commitment

  • In Vitro Studies on the Generation of Lymphocyte Diversity

    • J. J. T. Owen,
    • R. K. Jordan,
    • J. H. Robinson,
    • U. Singh,
    • and H. N. A. Willcox
    Cold Spring Harb Symp Quant Biol 1977 41: 129-137; doi:10.1101/SQB.1977.041.01.017

  • Studies of Generation of B-cell Diversity in Mouse, Man, and Chicken

    • M. D. Cooper,
    • J. F. Kearney,
    • P. M. Lydyard,
    • C. E. Grossi,
    • and A. R. Lawton
    Cold Spring Harb Symp Quant Biol 1977 41: 139-145; doi:10.1101/SQB.1977.041.01.018

  • Ontogeny of Murine B Lymphocytes: Development of Ig Synthesis and of Reactivities to Mitogens and to Anti-Ig-Antibodies

    • F. Melchers,
    • J. Andersson,
    • and R. A. Phillips
    Cold Spring Harb Symp Quant Biol 1977 41: 147-158; doi:10.1101/SQB.1977.041.01.019

  • Development and Modulation of B Lymphocytes: Studies on Newly Formed B Cells and Their Putative Precursors in the Hemopoietic Tissues of Mice

    • M. C. Raff
    Cold Spring Harb Symp Quant Biol 1977 41: 159-162; doi:10.1101/SQB.1977.041.01.020

  • Induction of Immunoglobulin Synthesis in Abelson Murine Leukemia Virus-transformed Mouse Lymphoma Cells in Culture

    • B. J. Weimann
    Cold Spring Harb Symp Quant Biol 1977 41: 163-164; doi:10.1101/SQB.1977.041.01.021

  • The Interplay of Evolution and Environment in B-cell Diversification

    • N. R. Klinman,
    • N. H. Sigal,
    • E. S. Metcalf,
    • S. K. Pierce,
    • and P. J. Gearhart
    Cold Spring Harb Symp Quant Biol 1977 41: 165-173; doi:10.1101/SQB.1977.041.01.022

  • Synthesis of Multiple Immunoglobulin Classes by Single Lymphocytes

    • B. Pernis,
    • L. Forni,
    • and A. L. Luzzati
    Cold Spring Harb Symp Quant Biol 1977 41: 175-183; doi:10.1101/SQB.1977.041.01.023

  • Immunoglobulin Receptors on Murine B Lymphocytes

    • E. S. Vitetta,
    • J. Cambier,
    • J. Forman,
    • J. R. Kettman,
    • D. Yuan,
    • and J. W. Uhr
    Cold Spring Harb Symp Quant Biol 1977 41: 185-191; doi:10.1101/SQB.1977.041.01.024

  • Functional and Structural Characterization of Immunoglobulin on Murine B Lymphocytes

    • R. M. E. Parkhouse,
    • E. R. Abney,
    • A. Bourgois,
    • and H. N. A. Willcox
    Cold Spring Harb Symp Quant Biol 1977 41: 193-200; doi:10.1101/SQB.1977.041.01.025

  • Origin and Differentiation of Lymphocytes Involved in the Secretory IgA Response

    • J. J. Cebra,
    • P. J. Gearhart,
    • R. Kamat,
    • S. M. Robertson,
    • and J. Tseng
    Cold Spring Harb Symp Quant Biol 1977 41: 201-215; doi:10.1101/SQB.1977.041.01.026

  • Mechanism of B-cell Activation and Self-Non-self Discrimination

    • G. Möller
    Cold Spring Harb Symp Quant Biol 1977 41: 217-226; doi:10.1101/SQB.1977.041.01.027

  • Growth and Maturation of Single Clones of Normal Murine T and B Lymphocytes In Vitro

    • J. Andersson,
    • A. Coutinho,
    • F. Melchers,
    • and T. Watanabe
    Cold Spring Harb Symp Quant Biol 1977 41: 227-236; doi:10.1101/SQB.1977.041.01.028

  • Hapten-specific B Lymphocytes: Enrichment, Cloning, Receptor Analysis, and Tolerance Induction

    • G. J. V. Nossal,
    • B. L. Pike,
    • J. W. Stocker,
    • J. E. Layton,
    • and J. W. Goding
    Cold Spring Harb Symp Quant Biol 1977 41: 237-243; doi:10.1101/SQB.1977.041.01.029

  • Regulation of Clonal B-lymphocyte Proliferation by Anti-immunoglobulin or Anti-Ia Antibodies

    • P. W. Kincade and
    • P. Ralph
    Cold Spring Harb Symp Quant Biol 1977 41: 245-250; doi:10.1101/SQB.1977.041.01.030

  • Cellular and Molecular Interactions in Control of B-cell Immunity and Tolerance

    • E. Diener,
    • C. Shiozawa,
    • B. Singh,
    • and K.-C. Lee
    Cold Spring Harb Symp Quant Biol 1977 41: 251-259; doi:10.1101/SQB.1977.041.01.031

Receptors

  • Lymphocyte Surface Immunoglobulins: Evolutionary Origins and Involvement in Activation

    • J. J. Marchalonis,
    • J. M. Decker,
    • D. DeLuca,
    • J. M. Moseley,
    • P. Smith,
    • and G. W. Warr
    Cold Spring Harb Symp Quant Biol 1977 41: 261-273; doi:10.1101/SQB.1977.041.01.032

  • Antigen-binding, Idiotypic Receptors from T Lymphocytes: An Analysis of Their Biochemistry, Genetics, and Use as Immunogens To Produce Specific Immune Tolerance

    • H. Binz and
    • H. Wigzell
    Cold Spring Harb Symp Quant Biol 1977 41: 275-284; doi:10.1101/SQB.1977.041.01.033

  • On the Structure of the T-cell Receptor for Antigen

    • U. Krawinkel,
    • M. Cramer,
    • C. Berek,
    • G. Hämmerling,
    • S. J. Black,
    • K. Rajewsky,
    • and K. Eichmann
    Cold Spring Harb Symp Quant Biol 1977 41: 285-294; doi:10.1101/SQB.1977.041.01.034

  • The Immune Response to Staphylococcal Nuclease: A Probe of Cellular and Humoral Antigen-specific Receptors

    • D. H. Sachs,
    • J. A. Berzofsky,
    • C. G. Fathman,
    • D. S. Pisetsky,
    • A. N. Schechter,
    • and R. H. Schwartz
    Cold Spring Harb Symp Quant Biol 1977 41: 295-306; doi:10.1101/SQB.1977.041.01.035

  • Functional Characterization of Rabbit Lymphocytes Carrying Fc Receptor

    • P.-A. Cazenave,
    • D. Juy,
    • and C. Bona
    Cold Spring Harb Symp Quant Biol 1977 41: 307-314; doi:10.1101/SQB.1977.041.01.036

  • Structural and Functional Heterogeneity of Fc Receptors

    • H. M. Grey,
    • C. L. Anderson,
    • C. H. Heusser,
    • B. K. Borthistle,
    • K. B. Von Eschen,
    • and J. M. Chiller
    Cold Spring Harb Symp Quant Biol 1977 41: 315-321; doi:10.1101/SQB.1977.041.01.037

THE MAJOR HISTOCOMPATIBILITY COMPLEX

Structure of the Molecular Products of the MHC

  • Structure of HL-A A and B Antigens Isolated from Cultured Human Lymphocytes

    • J. L. Strominger,
    • D. L. Mann,
    • P. Parham,
    • R. Robb,
    • T. Springer,
    • and C. Terhorst
    Cold Spring Harb Symp Quant Biol 1977 41: 323-329; doi:10.1101/SQB.1977.041.01.038

  • Structural Studies of β2-Microglobulin-associated and Other MHC Antigens

    • P. A. Peterson,
    • H. Anundi,
    • B. Curman,
    • L. Klareskog,
    • S. Kvist,
    • L. Östberg,
    • L. Rask,
    • L. Sandberg,
    • and K. Sege
    Cold Spring Harb Symp Quant Biol 1977 41: 331-339; doi:10.1101/SQB.1977.041.01.039

  • Comparative Chemical Analyses and Partial Amino Acid Sequences of the Heavy Chains of HL-A Antigens

    • E. Appella,
    • N. Tanigaki,
    • O. Henriksen,
    • D. Pressman,
    • D. F. Smith,
    • and T. Fairwell
    Cold Spring Harb Symp Quant Biol 1977 41: 341-342; doi:10.1101/SQB.1977.041.01.040

  • Structural Differences between Parent and Variant H-2K Glycoproteins from Mouse Strains Carrying H-2 Gene Mutations

    • S. G. Nathenson,
    • J. L. Brown,
    • B. M. Ewenstein,
    • T. Nisizawa,
    • D. W. Sears,
    • and J. H. Freed
    Cold Spring Harb Symp Quant Biol 1977 41: 343-349; doi:10.1101/SQB.1977.041.01.041

  • Structure of Murine Histocompatibility Antigens

    • B. A. Cunningham,
    • R. Henning,
    • R. J. Milner,
    • K. Reske,
    • J. A. Ziffer,
    • and G. M. Edelman
    Cold Spring Harb Symp Quant Biol 1977 41: 351-362; doi:10.1101/SQB.1977.041.01.042

  • Structural Studies of H-2 and TL Alloantigens

    • J. W. Uhr,
    • E. S. Vitetta,
    • J. Klein,
    • M. D. Poulik,
    • D. G. Klapper,
    • and J. D. Capra
    Cold Spring Harb Symp Quant Biol 1977 41: 363-368; doi:10.1101/SQB.1977.041.01.043

  • Chemical Characterization of Products of the H-2 Complex

    • J. Silver,
    • J. M. Cecka,
    • M. McMillan,
    • and L. Hood
    Cold Spring Harb Symp Quant Biol 1977 41: 369-377; doi:10.1101/SQB.1977.041.01.044

  • Human Ia Antigens — Purification and Molecular Structure

    • D. Snary,
    • C. Barnstable,
    • W. F. Bodmer,
    • P. Goodfellow,
    • and M. J. Crumpton
    Cold Spring Harb Symp Quant Biol 1977 41: 379-386; doi:10.1101/SQB.1977.041.01.045

  • Chemical and Immunological Characterization of HL-A-linked B-lymphocyte Alloantigens

    • T. A. Springer,
    • J. F. Kaufman,
    • L. A. Siddoway,
    • M. Giphart,
    • D. L. Mann,
    • C. Terhorst,
    • and J. L. Strominger
    Cold Spring Harb Symp Quant Biol 1977 41: 387-396; doi:10.1101/SQB.1977.041.01.046

  • The Guinea Pig MHC: Functional Significance and Structural Characterization

    • B. D. Schwartz,
    • A. M. Kask,
    • and E. M. Shevach
    Cold Spring Harb Symp Quant Biol 1977 41: 397-403; doi:10.1101/SQB.1977.041.01.047

  • Partial Amino Acid Sequences of MHC Products

    Cold Spring Harb Symp Quant Biol 1977 41: 405-406; doi:10.1101/SQB.1977.041.01.048

  • Analysis of Lymphocyte Surface Antigen Expression by the Use of Variant Cell Lines

    • R. Hyman and
    • I. Trowbridge
    Cold Spring Harb Symp Quant Biol 1977 41: 407-415; doi:10.1101/SQB.1977.041.01.049

Genetics of the MHC and Associated Products

  • Polymorphic B-cell Determinants in Man

    • J. J. van Rood,
    • A. van Leeuwen,
    • M. Jonker,
    • A. Termijtelen,
    • and B. A. Bradley
    Cold Spring Harb Symp Quant Biol 1977 41: 417-427; doi:10.1101/SQB.1977.041.01.050

  • Cellular Recognition of Major Histocompatibility Complex Antigens

    • F. H. Bach,
    • M. L. Bach,
    • O. J. Kuperman,
    • H. W. Sollinger,
    • and P. M. Sondel
    Cold Spring Harb Symp Quant Biol 1977 41: 429-441; doi:10.1101/SQB.1977.041.01.051

  • Genetics and Serology of HL-A-linked Human Ia Antigens

    • C. J. Barnstable,
    • E. A. Jones,
    • W. F. Bodmer,
    • J. G. Bodmer,
    • B. Arce-Gomez,
    • D. Snary,
    • and M. J. Crumpton
    Cold Spring Harb Symp Quant Biol 1977 41: 443-455; doi:10.1101/SQB.1977.041.01.052

  • Histocompatibility-2 System of Wild Mice IV. Ia and Ir Typing of Two Wild Mouse Populations

    • J. Klein,
    • C. F. Merryman,
    • P. H. Maurer,
    • M. Hauptfeld,
    • and M. B. Gardner
    Cold Spring Harb Symp Quant Biol 1977 41: 457-463; doi:10.1101/SQB.1977.041.01.053

  • Genetic Control of Specific Immune Responses and Immune Suppressions by I-region Genes

    • B. Benacerraf and
    • M. E. Dorf
    Cold Spring Harb Symp Quant Biol 1977 41: 465-475; doi:10.1101/SQB.1977.041.01.054

  • Serological and Functional Evidence for Further Subdivision of the I Regions of the H-2 Gene Complex

    • D. C. Shreffler,
    • C. S. David,
    • S. E. Cullen,
    • J. A. Frelinger,
    • and J. E. Niederhuber
    Cold Spring Harb Symp Quant Biol 1977 41: 477-487; doi:10.1101/SQB.1977.041.01.055

  • Functional and Genetic Analysis of Ia Antigens

    • H. O. McDevitt,
    • T. L. Delovitch,
    • and J. L. Press
    Cold Spring Harb Symp Quant Biol 1977 41: 489-496; doi:10.1101/SQB.1977.041.01.056

  • Selective Expression of Separate I-region Loci in Functionally Different Lymphocyte Subpopulations

    • D. B. Murphy,
    • K. Okumura,
    • L. A. Herzenberg,
    • L. A. Herzenberg,
    • and H. O. McDevitt
    Cold Spring Harb Symp Quant Biol 1977 41: 497-504; doi:10.1101/SQB.1977.041.01.057

Role of Histocompatibility Gene Products in T-cell Cytolysis

  • The Concept That Surveillance of Self Is Mediated Via the Same Set of Genes That Determines Recognition of Allogenic Cells

    • R. M. Zinkernagel and
    • P. C. Doherty
    Cold Spring Harb Symp Quant Biol 1977 41: 505-510; doi:10.1101/SQB.1977.041.01.058

  • F1 Hybrid Antiparental Cell-mediated Lympholysis: A Comparison with Bone Marrow Graft Rejection and with Cell-mediated Lympholysis to Alloantigens

    • G. M. Shearer,
    • G. Cudkowicz,
    • A. M. Schmitt-Verhulst,
    • T. G. Rehn,
    • H. Waksal,
    • and P. D. Evans
    Cold Spring Harb Symp Quant Biol 1977 41: 511-518; doi:10.1101/SQB.1977.041.01.059

  • Cytotoxic T-cell Response to Histocompatibility Antigens: The Role of H-2

    • M. J. Bevan
    Cold Spring Harb Symp Quant Biol 1977 41: 519-527; doi:10.1101/SQB.1977.041.01.060

  • Recognition of Alterations Induced by Early Vaccinia Surface Antigens and Dependence of Virus-specific Lysis on H-2 Antigen Concentration on Target Cells

    • U. Koszinowski,
    • H. Ertl,
    • H. Wekerle,
    • and R. Thomssen
    Cold Spring Harb Symp Quant Biol 1977 41: 529-537; doi:10.1101/SQB.1977.041.01.061

  • The Influence of H-2 Gene Products on Cell-mediated and Humoral Immune Responses

    • H. von Boehmer,
    • J. Sprent,
    • and W. Haas
    Cold Spring Harb Symp Quant Biol 1977 41: 539-545; doi:10.1101/SQB.1977.041.01.062

  • The Recognition of H-2 and Viral Antigens by Cytotoxic T Cells

    • J. W. Schrader,
    • R. Henning,
    • R. J. Milner,
    • and G. M. Edelman
    Cold Spring Harb Symp Quant Biol 1977 41: 547-557; doi:10.1101/SQB.1977.041.01.063

  • On the Possibility of Multiple T-cell Receptors

    • D. B. Wilson,
    • E. Heber-Katz,
    • J. Sprent,
    • and J. C. Howard
    Cold Spring Harb Symp Quant Biol 1977 41: 559-561; doi:10.1101/SQB.1977.041.01.064

Antigen Presentation and T-B Cell Interactions

  • Genetic Restriction of Macrophage-Lymphocyte Interactions in Secondary Antibody Responses In Vitro

    • C. W. Pierce,
    • J. A. Kapp,
    • and B. Benacerraf
    Cold Spring Harb Symp Quant Biol 1977 41: 563-570; doi:10.1101/SQB.1977.041.01.065

  • Genetic Restriction in T-lymphocyte Activation by Antigen-pulsed Peritoneal Exudate Cells

    • W. E. Paul,
    • E. M. Shevach,
    • D. W. Thomas,
    • S. F. Pickeral,
    • and A. S. Rosenthal
    Cold Spring Harb Symp Quant Biol 1977 41: 571-578; doi:10.1101/SQB.1977.041.01.066

  • Antigen Activation of T Lymphocytes: Influence of Major Histocompatibility Complex

    • J. F. A. P. Miller and
    • M. A. Vadas
    Cold Spring Harb Symp Quant Biol 1977 41: 579-588; doi:10.1101/SQB.1977.041.01.067

  • Regulatory Mechanisms in the Immune Response to Cell-surface Antigens

    • P. Lake and
    • N. A. Mitchison
    Cold Spring Harb Symp Quant Biol 1977 41: 589-595; doi:10.1101/SQB.1977.041.01.068

  • The Significance of T-B Collaboration across Haplotype Barriers

    • S. L. Swain,
    • P. E. Trefts,
    • H. Y.-S. Tse,
    • and R. W. Dutton
    Cold Spring Harb Symp Quant Biol 1977 41: 597-609; doi:10.1101/SQB.1977.041.01.069

  • The Role of the Histocompatibility Gene Complex in Lymphocyte Differentiation

    • D. H. Katz
    Cold Spring Harb Symp Quant Biol 1977 41: 611-624; doi:10.1101/SQB.1977.041.01.070

  • Comparison of B-cell Activation Factors

    • J. Klein
    Cold Spring Harb Symp Quant Biol 1977 41: 625-626; doi:10.1101/SQB.1977.041.01.071

IMMUNOGLOBULINS

Antibody Combining Site

  • Model-building Studies of Antigen-binding Sites: The Hapten-binding Site of MOPC-315

    • E. A. Padlan,
    • D. R. Davies,
    • I. Pecht,
    • D. Givol,
    • and C. Wright
    Cold Spring Harb Symp Quant Biol 1977 41: 627-637; doi:10.1101/SQB.1977.041.01.072

  • Three-dimensional Structure and Diversity of Immunoglobulins

    • R. J. Poljak,
    • L. M. Amzel,
    • B. L. Chen,
    • Y. Y. Chiu,
    • R. P. Phizackerley,
    • F. Saul,
    • and X. Ysern
    Cold Spring Harb Symp Quant Biol 1977 41: 639-645; doi:10.1101/SQB.1977.041.01.073

  • Origins of Antibody Diversity: Insights Gained from Amino Acid Sequence Studies of Elicited Antibodies

    • E. Haber,
    • M. N. Margolies,
    • and L. E. Cannon
    Cold Spring Harb Symp Quant Biol 1977 41: 647-659; doi:10.1101/SQB.1977.041.01.074

  • Primary Structural Differences in Myeloma Proteins That Bind the Same Haptens

    • M. Potter,
    • S. Rudikoff,
    • M. Vrana,
    • D. N. Rao,
    • and E. B. Mushinski
    Cold Spring Harb Symp Quant Biol 1977 41: 661-666; doi:10.1101/SQB.1977.041.01.075

  • Folding, Association, and Interactions of Domains in the Antibody Molecule

    • D. Givol,
    • J. Sharon,
    • J. Hochman,
    • M. Gavish,
    • D. Inbar,
    • I. Pecht,
    • I.-Z. Steinberg,
    • and J. Schlessinger
    Cold Spring Harb Symp Quant Biol 1977 41: 667-675; doi:10.1101/SQB.1977.041.01.076

Allotypes and Idiotypes

  • Rabbit Immunoglobulin Allotypes: Complexities of Their Genetics, Expression, Structural Basis, and Evolution

    • R. G. Mage,
    • G. O. Young-Cooper,
    • J. Rejnek,
    • A. A. Ansari,
    • C. B. Alexander,
    • E. Appella,
    • M. Carta-Sorcini,
    • S. Landucci-Tosi,
    • and R. M. Tosi
    Cold Spring Harb Symp Quant Biol 1977 41: 677-686; doi:10.1101/SQB.1977.041.01.077

  • V-region Genes for Rabbit Ig Heavy Chains

    • K. L. Knight,
    • W. J. Horng,
    • and S. Dray
    Cold Spring Harb Symp Quant Biol 1977 41: 687-688; doi:10.1101/SQB.1977.041.01.078

  • The Response of Rabbits to Streptococcal Hyperimmunization

    • B. A. Fraser,
    • A. P. Johnstone,
    • S. M. Gordon,
    • and T. J. Kindt
    Cold Spring Harb Symp Quant Biol 1977 41: 689-698; doi:10.1101/SQB.1977.041.01.079

  • Structure and Immunosuppression of a Cross-reactive Idiotype Associated with Anti-p-azophenylarsonate Antibodies of Strain-A Mice

    • S.-T. Ju,
    • F. L. Owen,
    • and A. Nisonoff
    Cold Spring Harb Symp Quant Biol 1977 41: 699-707; doi:10.1101/SQB.1977.041.01.080

  • Idiotypes and Anti-idiotypes as Probes in Analysis of Immunoregulation

    • H. Cosenza,
    • A. A. Augustin,
    • and M. H. Julius
    Cold Spring Harb Symp Quant Biol 1977 41: 709-718; doi:10.1101/SQB.1977.041.01.081

  • Immune Responses of BALB/c Mice to the Idiotype of T15 and of Other Myeloma Proteins of BALB/c Origin: Implications for an Immune Network and Antibody Multispecificity

    • N. Sakato,
    • C. A. Janeway, Jr.,
    • and H. N. Eisen
    Cold Spring Harb Symp Quant Biol 1977 41: 719-724; doi:10.1101/SQB.1977.041.01.082

  • Uniformity in a Clonal Repertoire: A Case for a Germ-line Basis of Antibody Diversity

    • J. L. Claflin and
    • S. Rudikoff
    Cold Spring Harb Symp Quant Biol 1977 41: 725-734; doi:10.1101/SQB.1977.041.01.083

  • Inheritance of Antibody Specificity. IV. Control of Related Molecular Species by One VH Gene

    • O. Mäkelä and
    • K. Karjalainen
    Cold Spring Harb Symp Quant Biol 1977 41: 735-741; doi:10.1101/SQB.1977.041.01.084

  • On the Genetic Dissection of a Specific Humoral Immune Response to α(1,3) Dextran

    • W. Geckeler,
    • B. Blomberg,
    • C. de Preval,
    • and M. Cohn
    Cold Spring Harb Symp Quant Biol 1977 41: 743-748; doi:10.1101/SQB.1977.041.01.085

Generation of Diversity: 1. Biological Aspects

  • The Life Style of B Cells — Cellular Proliferation and the Invariancy of IgG

    • B. A. Askonas and
    • J. R. North
    Cold Spring Harb Symp Quant Biol 1977 41: 749-759; doi:10.1101/SQB.1977.041.01.086

  • Evolution in Microcosm: The Rapid Somatic Diversification of Lymphocytes

    • A. J. Cunningham
    Cold Spring Harb Symp Quant Biol 1977 41: 761-770; doi:10.1101/SQB.1977.041.01.087

  • The Ontogenesis of Lymphocyte Diversity in Anuran Amphibians

    • L. Du Pasquier and
    • M. R. Wabl
    Cold Spring Harb Symp Quant Biol 1977 41: 771-779; doi:10.1101/SQB.1977.041.01.088

  • Regulation of Immunoglobulin Expression in Mouse Myeloma Cells

    • D. H. Margulies,
    • W. Cieplinski,
    • B. Dharmgrongartama,
    • M. L. Gefter,
    • S. L. Morrison,
    • T. Kelly,
    • and M. D. Scharff
    Cold Spring Harb Symp Quant Biol 1977 41: 781-791; doi:10.1101/SQB.1977.041.01.089

  • Somatic Cell Genetics of Antibody-secreting Cells: Studies of Clonal Diversification and Analysis by Cell Fusion

    • C. Milstein,
    • K. Adetugbo,
    • N. J. Cowan,
    • G. Köhler,
    • D. S. Secher,
    • and C. D. Wilde
    Cold Spring Harb Symp Quant Biol 1977 41: 793-803; doi:10.1101/SQB.1977.041.01.090

  • The IB-peptide Marker and the Ly-3 Surface Alloantigen: Structural Studies of a Vκ-region Polymorphism and a T-cell Marker Determined by Linked Genes

    • P. D. Gottlieb and
    • P. J. Durda
    Cold Spring Harb Symp Quant Biol 1977 41: 805-815; doi:10.1101/SQB.1977.041.01.091

Generation of Diversity: 2. Structural Aspects

  • The Structure and Genetics of Mouse Immunoglobulins: An Analysis of NZB Myeloma Proteins and Sets of BALB/c Myeloma Proteins Binding Particular Haptens

    • L. Hood,
    • E. Loh,
    • J. Hubert,
    • P. Barstad,
    • B. Eaton,
    • P. Early,
    • J. Fuhrman,
    • N. Johnson,
    • M. Kronenberg,
    • and J. Schilling
    Cold Spring Harb Symp Quant Biol 1977 41: 817-836; doi:10.1101/SQB.1977.041.01.092

  • Genetic Control of Antibody Variable Regions

    • M. Weigert and
    • R. Riblet
    Cold Spring Harb Symp Quant Biol 1977 41: 837-846; doi:10.1101/SQB.1977.041.01.093

  • Identical Hypervariable Regions in Light Chains of Differing Vκ Subgroups

    • J. D. Capra,
    • D. G. Klapper,
    • A. S. Tung,
    • and A. Nisonoff
    Cold Spring Harb Symp Quant Biol 1977 41: 847-853; doi:10.1101/SQB.1977.041.01.094

  • Origin of Immunoglobulin Gene Diversity: The Evidence and a Restriction-modification Model

    • P. Leder,
    • T. Honjo,
    • J. Seidman,
    • and D. Swan
    Cold Spring Harb Symp Quant Biol 1977 41: 855-862; doi:10.1101/SQB.1977.041.01.095

  • The Significance of Hybridization Kinetic Experiments for Theories of Antibody Diversity

    • G. P. Smith
    Cold Spring Harb Symp Quant Biol 1977 41: 863-875; doi:10.1101/SQB.1977.041.01.096

  • Somatic Changes in the Content and Context of Immunoglobulin Genes

    • S. Tonegawa,
    • N. Hozumi,
    • G. Matthyssens,
    • and R. Schuller
    Cold Spring Harb Symp Quant Biol 1977 41: 877-889; doi:10.1101/SQB.1977.041.01.097

Summary

  • Summary: Understanding Selective Molecular Recognition

    • G. M. Edelman
    Cold Spring Harb Symp Quant Biol 1977 41: 891-902; doi:10.1101/SQB.1977.041.01.098
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This Volume

Origins of Lymphocyte Diversity vol. 41, 1977
Cover
  1. Introduction
  2. LYMPHOCYTE FUNCTION
    1. T-cell Markers and Differentiation
    2. Helper and Suppressor T Cells and Their Products
    3. B-cell Differentiation and Commitment
    4. Receptors
  4. THE MAJOR HISTOCOMPATIBILITY COMPLEX
    1. Structure of the Molecular Products of the MHC
    2. Genetics of the MHC and Associated Products
    3. Role of Histocompatibility Gene Products in T-cell Cytolysis
    4. Antigen Presentation and T-B Cell Interactions
  6. IMMUNOGLOBULINS
    1. Antibody Combining Site
    2. Allotypes and Idiotypes
    3. Generation of Diversity: 1. Biological Aspects
    4. Generation of Diversity: 2. Structural Aspects
    5. Summary

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