diff --git a/site/src/modules/terminal/WorkspaceTerminal.tsx b/site/src/modules/terminal/WorkspaceTerminal.tsx
index 058fdd7ff7fad..a1f96888b0917 100644
--- a/site/src/modules/terminal/WorkspaceTerminal.tsx
+++ b/site/src/modules/terminal/WorkspaceTerminal.tsx
@@ -240,6 +240,30 @@ export const WorkspaceTerminal = ({
 			}),
 		);
 
+		// OSC 52 clipboard support. Programs like tmux send this escape
+		// sequence to copy text to the host's system clipboard.
+		nextTerminal.parser.registerOscHandler(52, (data) => {
+			const separatorIndex = data.indexOf(";");
+			if (separatorIndex === -1) {
+				return false;
+			}
+			const payload = data.slice(separatorIndex + 1);
+			// A "?" payload is a clipboard read query. Responding would
+			// require writing back to the PTY, which is not supported.
+			if (!payload || payload === "?") {
+				return false;
+			}
+			try {
+				const bytes = Uint8Array.from(atob(payload), (c) => c.charCodeAt(0));
+				const decoded = new TextDecoder().decode(bytes);
+				void copyToClipboard(decoded);
+			} catch {
+				// Invalid base64; ignore.
+				return false;
+			}
+			return true;
+		});
+
 		const copySelection = () => {
 			const selection = nextTerminal.getSelection();
 			if (selection) {
diff --git a/site/src/pages/TerminalPage/TerminalPage.test.tsx b/site/src/pages/TerminalPage/TerminalPage.test.tsx
index 74f5caabc7183..4c1269c54f48f 100644
--- a/site/src/pages/TerminalPage/TerminalPage.test.tsx
+++ b/site/src/pages/TerminalPage/TerminalPage.test.tsx
@@ -1,7 +1,7 @@
 import { screen, waitFor } from "@testing-library/react";
 import userEvent from "@testing-library/user-event";
 import { HttpResponse, http } from "msw";
-import { afterEach, describe, expect, it, vi } from "vitest";
+import { afterEach, beforeEach, describe, expect, it, vi } from "vitest";
 import { API } from "#/api/api";
 import type { Workspace } from "#/api/typesGenerated";
 import {
@@ -249,6 +249,79 @@ describe("TerminalPage", () => {
 		expect(closeSpy).toHaveBeenCalled();
 	});
 
+	describe("OSC 52 clipboard", () => {
+		let writeTextMock: ReturnType<typeof vi.fn>;
+		let originalClipboard: PropertyDescriptor | undefined;
+
+		beforeEach(() => {
+			originalClipboard = Object.getOwnPropertyDescriptor(
+				navigator,
+				"clipboard",
+			);
+			writeTextMock = vi.fn().mockResolvedValue(undefined);
+			Object.defineProperty(navigator, "clipboard", {
+				value: { writeText: writeTextMock, readText: vi.fn() },
+				writable: true,
+				configurable: true,
+			});
+		});
+
+		afterEach(() => {
+			if (originalClipboard) {
+				Object.defineProperty(navigator, "clipboard", originalClipboard);
+			}
+		});
+
+		it("copies to clipboard via OSC 52", async () => {
+			const ws = createWorkspaceTerminalWebSocket();
+			await renderTerminal();
+			await ws.nextMessage;
+
+			// OSC 52 sequence per #16577:
+			// printf "\033]52;c;$(echo -n 'Coder is Cool' | base64)\a"
+			const base64 = btoa("Coder is Cool");
+			ws.send(`\x1b]52;c;${base64}\x07`);
+
+			await waitFor(() => {
+				expect(writeTextMock).toHaveBeenCalledWith("Coder is Cool");
+			});
+		});
+
+		it("ignores OSC 52 with missing separator", async () => {
+			const ws = createWorkspaceTerminalWebSocket();
+			await renderTerminal();
+			await ws.nextMessage;
+
+			ws.send("\x1b]52;no-separator\x07");
+
+			// Give the parser time to process, then verify no clipboard write.
+			await new Promise((r) => setTimeout(r, 100));
+			expect(writeTextMock).not.toHaveBeenCalled();
+		});
+
+		it("ignores OSC 52 clipboard read query", async () => {
+			const ws = createWorkspaceTerminalWebSocket();
+			await renderTerminal();
+			await ws.nextMessage;
+
+			ws.send("\x1b]52;c;?\x07");
+
+			await new Promise((r) => setTimeout(r, 100));
+			expect(writeTextMock).not.toHaveBeenCalled();
+		});
+
+		it("ignores OSC 52 with invalid base64", async () => {
+			const ws = createWorkspaceTerminalWebSocket();
+			await renderTerminal();
+			await ws.nextMessage;
+
+			ws.send("\x1b]52;c;!!!invalid-base64!!!\x07");
+
+			await new Promise((r) => setTimeout(r, 100));
+			expect(writeTextMock).not.toHaveBeenCalled();
+		});
+	});
+
 	it("skips confirmation dialog for trusted app commands", async () => {
 		// Override the workspace response so the agent has an app with
 		// a command that matches the ?app= slug.