Titles explains it. Basically I've got a sheet with a couple of event functions attached to handle refreshing a chart and resizing the column widths.

Jspreadsheet CE is initially called like this:

const spreadsheet = jspreadsheet( spreadsheet_div, {
	worksheets: [{
		data: data,
		allowComments: false,
		minDimensions: [37, 17]
	}],
	onload: function(spreadsheet) {
		// Run an auto width function to make the column widths match content
		const worksheet = spreadsheet.worksheets[spreadsheet.getWorksheetActive()];
		autoWidth(worksheet);
	},
	onafterchanges: function(worksheet, records) {
		// Run an auto width function to make the column widths match content
		autoWidth(worksheet, records);

		// Update chart on spreadsheet changes
		refreshChart();
	}
});

Then when needed I run a setData call like this:

spreadsheet.setData( response.data );

The docs say that onload will run when setData is called to change/set the data in the sheet but this does not seem to actually happen. You'd potentially think that onafterchanges might run too since cells are changing, but it doesn't run either.

It's also worth noting that none of this fires after undo either, which seems counterintuitive in particular with onafterchanges.

This is with the latest (as I write this) v5 version of Jspreadsheet CE.