diff --git a/doc/source/reference/c-api/config.rst b/doc/source/reference/c-api/config.rst
index 87130699bbf8..963a106f8a76 100644
--- a/doc/source/reference/c-api/config.rst
+++ b/doc/source/reference/c-api/config.rst
@@ -118,14 +118,3 @@ Compiler directives
 .. c:macro:: NPY_LIKELY
 .. c:macro:: NPY_UNLIKELY
 .. c:macro:: NPY_UNUSED
-
-
-Interrupt Handling
-------------------
-
-.. c:macro:: NPY_INTERRUPT_H
-.. c:macro:: NPY_SIGSETJMP
-.. c:macro:: NPY_SIGLONGJMP
-.. c:macro:: NPY_SIGJMP_BUF
-.. c:macro:: NPY_SIGINT_ON
-.. c:macro:: NPY_SIGINT_OFF