diff --git a/Lib/concurrent/futures/thread.py b/Lib/concurrent/futures/thread.py
index 51c942f51abd37..fc39682bb5849e 100644
--- a/Lib/concurrent/futures/thread.py
+++ b/Lib/concurrent/futures/thread.py
@@ -41,6 +41,7 @@ def _python_exit():
     os.register_at_fork(before=_global_shutdown_lock.acquire,
                         after_in_child=_global_shutdown_lock._at_fork_reinit,
                         after_in_parent=_global_shutdown_lock.release)
+    os.register_at_fork(after_in_child=_threads_queues.clear)
 
 
 class _WorkItem(object):
diff --git a/Misc/NEWS.d/next/Library/2023-02-15-23-54-42.gh-issue-88110.KU6erv.rst b/Misc/NEWS.d/next/Library/2023-02-15-23-54-42.gh-issue-88110.KU6erv.rst
new file mode 100644
index 00000000000000..9f6003a1f0556a
--- /dev/null
+++ b/Misc/NEWS.d/next/Library/2023-02-15-23-54-42.gh-issue-88110.KU6erv.rst
@@ -0,0 +1,2 @@
+Fix multiprocessing.Process exiting with code 1 even on successful run when
+threads are used in the same application too.