diff --git a/Misc/NEWS.d/next/Build/2018-11-16-15-19-09.bpo-35264.h5GxH3.rst b/Misc/NEWS.d/next/Build/2018-11-16-15-19-09.bpo-35264.h5GxH3.rst
new file mode 100644
index 00000000000000..d17968a52debf4
--- /dev/null
+++ b/Misc/NEWS.d/next/Build/2018-11-16-15-19-09.bpo-35264.h5GxH3.rst
@@ -0,0 +1 @@
+Fix SSL module build with OpenSSL 1.1.0
diff --git a/Modules/_ssl.c b/Modules/_ssl.c
index a96c41926036cc..c80437eef78fbf 100644
--- a/Modules/_ssl.c
+++ b/Modules/_ssl.c
@@ -1586,7 +1586,7 @@ static PyObject *PySSL_version(PySSLSocket *self)
     return PyUnicode_FromString(version);
 }
 
-#if defined(OPENSSL_NPN_NEGOTIATED) && !defined(OPENSSL_NO_NEXTPROTONEG)
+#if HAVE_NPN
 static PyObject *PySSL_selected_npn_protocol(PySSLSocket *self) {
     const unsigned char *out;
     unsigned int outlen;
@@ -2114,7 +2114,7 @@ static PyMethodDef PySSLMethods[] = {
      PySSL_peercert_doc},
     {"cipher", (PyCFunction)PySSL_cipher, METH_NOARGS},
     {"version", (PyCFunction)PySSL_version, METH_NOARGS},
-#ifdef OPENSSL_NPN_NEGOTIATED
+#if HAVE_NPN
     {"selected_npn_protocol", (PyCFunction)PySSL_selected_npn_protocol, METH_NOARGS},
 #endif
 #if HAVE_ALPN