diff --git a/Lib/pathlib.py b/Lib/pathlib.py
index 65ff0ee1977f80..02eb5c25981e31 100644
--- a/Lib/pathlib.py
+++ b/Lib/pathlib.py
@@ -359,9 +359,9 @@ def __init__(self, *args):
         paths = []
         for arg in args:
             if isinstance(arg, PurePath):
-                if arg._flavour is ntpath and self._flavour is posixpath:
+                if arg._flavour is not self._flavour:
                     # GH-103631: Convert separators for backwards compatibility.
-                    paths.extend(path.replace('\\', '/') for path in arg._raw_paths)
+                    paths.append(arg.as_posix())
                 else:
                     paths.extend(arg._raw_paths)
             else:
diff --git a/Lib/test/test_pathlib.py b/Lib/test/test_pathlib.py
index ca604df70a9a4e..4437f878004c70 100644
--- a/Lib/test/test_pathlib.py
+++ b/Lib/test/test_pathlib.py
@@ -831,6 +831,14 @@ class PureWindowsPathTest(_BasePurePathTest, unittest.TestCase):
             ],
     })
 
+    def test_constructor_nested_foreign_flavour(self):
+        # See GH-125069.
+        p1 = pathlib.PurePosixPath('b/c:\\d')
+        p2 = pathlib.PurePosixPath('b/', 'c:\\d')
+        self.assertEqual(p1, p2)
+        self.assertEqual(self.cls(p1), self.cls('b/c:/d'))
+        self.assertEqual(self.cls(p2), self.cls('b/c:/d'))
+
     def test_drive_root_parts(self):
         check = self._check_drive_root_parts
         # First part is anchored.
diff --git a/Misc/NEWS.d/next/Library/2024-10-08-21-17-16.gh-issue-125069.0RP0Mx.rst b/Misc/NEWS.d/next/Library/2024-10-08-21-17-16.gh-issue-125069.0RP0Mx.rst
new file mode 100644
index 00000000000000..73d5fa59303d4d
--- /dev/null
+++ b/Misc/NEWS.d/next/Library/2024-10-08-21-17-16.gh-issue-125069.0RP0Mx.rst
@@ -0,0 +1,4 @@
+Fix an issue where providing a :class:`pathlib.PurePath` object as an
+initializer argument to a second :class:`~pathlib.PurePath` object with a
+different flavour resulted in arguments to the former object's initializer
+ being joined by the latter object's flavour.