diff --git a/Lib/ftplib.py b/Lib/ftplib.py
index 50771e8c17c250..06be1d66bbde51 100644
--- a/Lib/ftplib.py
+++ b/Lib/ftplib.py
@@ -787,24 +787,24 @@ def abort(self):
     all_errors = (Error, OSError, EOFError, ssl.SSLError)
 
 
-_150_re = None
-
 def parse150(resp):
     '''Parse the '150' response for a RETR request.
     Returns the expected transfer size or None; size is not guaranteed to
     be present in the 150 message.
     '''
-    if resp[:3] != '150':
+    if not resp.startswith('150'):
         raise error_reply(resp)
-    global _150_re
-    if _150_re is None:
-        import re
-        _150_re = re.compile(
-            r"150 .* \((\d+) bytes\)", re.IGNORECASE | re.ASCII)
-    m = _150_re.match(resp)
-    if not m:
+
+    start = resp.find('(')
+    end = resp.lower().find(' bytes)')
+
+    if start == -1 or end == -1 or start >= end:
+        return None
+
+    try:
+        return int(resp[start + 1:end])
+    except ValueError:
         return None
-    return int(m.group(1))
 
 
 _227_re = None
diff --git a/Misc/NEWS.d/next/Library/2025-02-18-05-00-24.gh-issue-130167.e0MXUp.rst b/Misc/NEWS.d/next/Library/2025-02-18-05-00-24.gh-issue-130167.e0MXUp.rst
new file mode 100644
index 00000000000000..31d6799dff8742
--- /dev/null
+++ b/Misc/NEWS.d/next/Library/2025-02-18-05-00-24.gh-issue-130167.e0MXUp.rst
@@ -0,0 +1,2 @@
+Improve speed of :func:`ftplib.parse150` by replacing :mod:`re` with
+:func:`find` method. Patch by Semyon Moroz.