diff --git a/Mac/BuildScript/build-installer.py b/Mac/BuildScript/build-installer.py
index 7e89a3bc82ae24..4a115e1a5f7732 100755
--- a/Mac/BuildScript/build-installer.py
+++ b/Mac/BuildScript/build-installer.py
@@ -358,9 +358,9 @@ def library_recipes():
                   ),
           ),
           dict(
-              name="SQLite 3.37.2",
-              url="https://sqlite.org/2022/sqlite-autoconf-3370200.tar.gz",
-              checksum='683cc5312ee74e71079c14d24b7a6d27',
+              name="SQLite 3.38.1",
+              url="https://sqlite.org/2022/sqlite-autoconf-3380100.tar.gz",
+              checksum="5af57892dc0993af596bef56931db23f",
               extra_cflags=('-Os '
                             '-DSQLITE_ENABLE_FTS5 '
                             '-DSQLITE_ENABLE_FTS4 '
diff --git a/Misc/NEWS.d/next/macOS/2022-03-13-11-11-31.bpo-46907.Ql0z1E.rst b/Misc/NEWS.d/next/macOS/2022-03-13-11-11-31.bpo-46907.Ql0z1E.rst
new file mode 100644
index 00000000000000..365081f78e22c4
--- /dev/null
+++ b/Misc/NEWS.d/next/macOS/2022-03-13-11-11-31.bpo-46907.Ql0z1E.rst
@@ -0,0 +1 @@
+Update macOS installer to SQLite 3.38.1.