diff --git a/CHANGELOG.md b/CHANGELOG.md
index ba1a6d78..92a19a3a 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -14,6 +14,8 @@ New features:
   Patch by [Victorien Plot](https://github.com/Viicos).
 - Add `typing_extensions.Reader` and `typing_extensions.Writer`. Patch by
   Sebastian Rittau.
+- Add support for sentinels ([PEP 661](https://peps.python.org/pep-0661/)). Patch by
+  [Victorien Plot](https://github.com/Viicos).
 
 # Release 4.13.2 (April 10, 2025)
 
diff --git a/doc/index.rst b/doc/index.rst
index 68402faf..21d6fa60 100644
--- a/doc/index.rst
+++ b/doc/index.rst
@@ -1027,6 +1027,34 @@ Capsule objects
    .. versionadded:: 4.12.0
 
 
+Sentinel objects
+~~~~~~~~~~~~~~~~
+
+.. class:: Sentinel(name, repr=None)
+
+   A type used to define sentinel values. The *name* argument should be the
+   name of the variable to which the return value shall be assigned.
+
+   If *repr* is provided, it will be used for the :meth:`~object.__repr__`
+   of the sentinel object. If not provided, ``"<name>"`` will be used.
+
+   Example::
+
+      >>> from typing_extensions import Sentinel, assert_type
+      >>> MISSING = Sentinel('MISSING')
+      >>> def func(arg: int | MISSING = MISSING) -> None:
+      ...     if arg is MISSING:
+      ...         assert_type(arg, MISSING)
+      ...     else:
+      ...         assert_type(arg, int)
+      ...
+      >>> func(MISSING)
+
+   .. versionadded:: 4.14.0
+
+      See :pep:`661`
+
+
 Pure aliases
 ~~~~~~~~~~~~
 
diff --git a/src/test_typing_extensions.py b/src/test_typing_extensions.py
index a7953dc5..c23e94b7 100644
--- a/src/test_typing_extensions.py
+++ b/src/test_typing_extensions.py
@@ -65,6 +65,7 @@
     ReadOnly,
     Required,
     Self,
+    Sentinel,
     Set,
     Tuple,
     Type,
@@ -9096,5 +9097,44 @@ def test_invalid_special_forms(self):
             self.assertIs(evaluate_forward_ref(typing.ForwardRef("ClassVar", is_argument=False), globals=vars(typing)), ClassVar)
 
 
+class TestSentinels(BaseTestCase):
+    def test_sentinel_no_repr(self):
+        sentinel_no_repr = Sentinel('sentinel_no_repr')
+
+        self.assertEqual(sentinel_no_repr._name, 'sentinel_no_repr')
+        self.assertEqual(repr(sentinel_no_repr), '<sentinel_no_repr>')
+
+    def test_sentinel_explicit_repr(self):
+        sentinel_explicit_repr = Sentinel('sentinel_explicit_repr', repr='explicit_repr')
+
+        self.assertEqual(repr(sentinel_explicit_repr), 'explicit_repr')
+
+    @skipIf(sys.version_info < (3, 10), reason='New unions not available in 3.9')
+    def test_sentinel_type_expression_union(self):
+        sentinel = Sentinel('sentinel')
+
+        def func1(a: int | sentinel = sentinel): pass
+        def func2(a: sentinel | int = sentinel): pass
+
+        self.assertEqual(func1.__annotations__['a'], Union[int, sentinel])
+        self.assertEqual(func2.__annotations__['a'], Union[sentinel, int])
+
+    def test_sentinel_not_callable(self):
+        sentinel = Sentinel('sentinel')
+        with self.assertRaisesRegex(
+            TypeError,
+            "'Sentinel' object is not callable"
+        ):
+            sentinel()
+
+    def test_sentinel_not_picklable(self):
+        sentinel = Sentinel('sentinel')
+        with self.assertRaisesRegex(
+            TypeError,
+            "Cannot pickle 'Sentinel' object"
+        ):
+            pickle.dumps(sentinel)
+
+
 if __name__ == '__main__':
     main()
diff --git a/src/typing_extensions.py b/src/typing_extensions.py
index 1ab6220d..d4e92a4c 100644
--- a/src/typing_extensions.py
+++ b/src/typing_extensions.py
@@ -89,6 +89,7 @@
     'overload',
     'override',
     'Protocol',
+    'Sentinel',
     'reveal_type',
     'runtime',
     'runtime_checkable',
@@ -4210,6 +4211,42 @@ def evaluate_forward_ref(
         )
 
 
+class Sentinel:
+    """Create a unique sentinel object.
+
+    *name* should be the name of the variable to which the return value shall be assigned.
+
+    *repr*, if supplied, will be used for the repr of the sentinel object.
+    If not provided, "<name>" will be used.
+    """
+
+    def __init__(
+        self,
+        name: str,
+        repr: typing.Optional[str] = None,
+    ):
+        self._name = name
+        self._repr = repr if repr is not None else f'<{name}>'
+
+    def __repr__(self):
+        return self._repr
+
+    if sys.version_info < (3, 11):
+        # The presence of this method convinces typing._type_check
+        # that Sentinels are types.
+        def __call__(self, *args, **kwargs):
+            raise TypeError(f"{type(self).__name__!r} object is not callable")
+
+    def __or__(self, other):
+        return typing.Union[self, other]
+
+    def __ror__(self, other):
+        return typing.Union[other, self]
+
+    def __getstate__(self):
+        raise TypeError(f"Cannot pickle {type(self).__name__!r} object")
+
+
 # Aliases for items that are in typing in all supported versions.
 # We use hasattr() checks so this library will continue to import on
 # future versions of Python that may remove these names.