I've run into a bit of an issue with an App + Worker setup and Statamic forms with attachments that use the file field.
Because Statamic assumes that the temp upload path is local, when the worker tried to attach a file it's unable to access it.
fopen(): Failed to open stream: No such file or directory.
https://github.com/statamic/cms/blob/5.x/src/Assets/Uploader.php#L59
There are a number of hard coded references to the local file system with will cause issues for a distributed system.
This was only an issue with Forms from what we've seen.