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Cefuroxime: Uses and Nursing Guide

Cefuroxime axetil (brand name Ceftin) is a second-generation cephalosporin antibiotic indicated for a wide range of bacterial infections including respiratory, urinary, skin and soft tissue infections. Common side effects include gastrointestinal issues like diarrhea and nausea, as well as rashes and hypersensitivity reactions. Nurses should monitor patients taking cefuroxime axetil for signs of side effects or superinfection, ensure proper administration such as taking with food, and notify the prescriber of any issues.

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Jon Adam Bermudez Samatra
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96 views1 page

Cefuroxime: Uses and Nursing Guide

Cefuroxime axetil (brand name Ceftin) is a second-generation cephalosporin antibiotic indicated for a wide range of bacterial infections including respiratory, urinary, skin and soft tissue infections. Common side effects include gastrointestinal issues like diarrhea and nausea, as well as rashes and hypersensitivity reactions. Nurses should monitor patients taking cefuroxime axetil for signs of side effects or superinfection, ensure proper administration such as taking with food, and notify the prescriber of any issues.

Uploaded by

Jon Adam Bermudez Samatra
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Generic Name Cefuroxime Axetil

Brand Name Ceftin *P.O.+

Indications Pharyngitis, tonsillitis, infections of the urinary and lower respiratory tracts, and Streptococcus pneumoniae and S. pyogenes, Haemophillus influenzae, Staphylococcus aureus, Escherichia coli, Moraxella catarrhalis (including betalactamase-producing strains), Neisseria gonorrheae, and Klebsiella and Enterobacter species. * Serious lower respiratory tract infections, UTIs, skin and skin-structure infections, bone and joint infections, septicemia, meningitis, and gonorrhea * Uncomplicated UTIs * Otitis Media * Pharyngitis and Tonsillitis * Perioperative Prevention * Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi * Secondary bacterial infection of acute bronchitis * Uncomplicated gonorrhea * Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenza (only strains that dont produce beta-lactamase)

Action Secondgeneration

Side effects CV: phlebitis, thrombophlebitis GI: pseudomembranous colitis, nausea, anorexia, vomiting, diarrhea eosinophilia, hemolytic anemia, thrombocytopenia Skin: maculopapular and erythematous rashes, urticaria, pain, induration, sterile abscesses, temperature elevation, tissue sloughing at intramuscular injection site Other: hypersensitivity reactions, serum sickness, anaphylaxis. Effects on Lab Test Results: bilirubin, and LDH levels. May decrease hemoglobin and hematocrit level. * May increase PT and INR and eosinophil count. May decrease neutrophil and platelet counts. * May falsely increase serum or urine creatinine level in tests using Jaffe reaction. May cause false-positive results of Coombs test and urine glucose tests using cupric sulfate (Benedicts reagent or Clinitest).

Nursing responsibilities *Before administering, make sure patient is not allergic to penicillins or cephalosporins. * Absorption of cefuroxime axetil is enhanced by food. * High-fat meals increased drug bioavailability. *Cefuroxime axetil film-coated tablet and oral suspension are not bioequivalent. * If large doses are given, therapy is prolonged, or patient is at high risk, monitor patient for signs and * Unlike other second generation cephalosporins, cefuroxime can cross the blood-brain-barrier. * Take medication as prescribed, even after feeling better. * Take oral form with food. * If suspension is being used, shake the container well before measuring dose. * Notify prescriber about rashes or superinfections. * Notify prescriber about loose stools or diarrhea.

skin and skin-structure infections caused by cephalosporin Cefuroxime Zinacef Sodium *Parenteral+ wall synthesis, promoting osmotic instability; usually bactericidal.

that inhibits cell- Hematologic: transient neutropenia,

* May increase ALT, AST, alkaline phosphatase, symptoms of superinfection.

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