Seat No.
: _____
Enrolment No.______
GUJARAT TECHNOLOGICAL UNIVERSITY
Diploma Pharmacy First Year Remedial Examination September 2009
Subject code: 410004
Subject Name: Biochemistry & clinical pathology
Date: 19/09/2009
Time: 02:30pm-5:30pm
Instructions:
Total Marks: 80
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1
(a) Define carbohydrate. Classify it with examples. Write its biomedical
importance.
(b) Write notes on Mucopolysaccharides and proteoglycans.
(c) Describe citric acid cycle with its energetic.
Q.2
(a) Define and classify vitamins. Write chemistry, source, functions and
deficiency of Vitamin A.
(b) Write functions of following :
1. Iron
2. Calcium
3. Zinc
(c) Discuss co-enzymatic role of thiamine, riboflavin and folic acid.
Q.3
(a) Define enzymes. Classify it with suitable examples. Discuss factors
affecting enzyme action.
(b) Write clinical importance of following enzymes :
1. SGPT
2. LDH
3. Creatine phosphokinase.
(c) Differentiate between : competitive & non-competitive inhibition
Q.4
(a) Define pentose phosphate pathways. Describe flow charts of pentose
phosphate pathways. Write in brief about significance of pentose
phosphate pathways.
(b) Classify protein on the basis of functional properties. Write in brief
about structural organization of protein.
(c) What is urea cycle? Outline its steps involved in urea formation.
Q.5
(a) What are lipids? Classify it with examples. Write biomedical
importance of lipids.
(b) Define phospholipid. Classify it. Write in brief about phospholipases
and biomedical importance of phospholipids.
(c) Write biomedical importance of cholesterol. Write detail notes on de
novo synthesis of cholesterol.
Q. 6
(a) Give clinical significance of following abnormal constituents of
urine.
1. Ketone bodies.
2. Blood
3. Protein.
(b) Write notes on digestion, absorption & transport of lipids to liver.
(c) Describe glycolysis with its energetic.
Q.7
(a) Write notes on protein synthesis.
Write notes on lipogenesis.
(b)
Write
chemistry, dietary source, functions and deficiency disorder of
(c)
folic acid.
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