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Drug Study Proglin

Proglin is an anti-diabetic drug classified as an islet enhancer and DPP-4 inhibitor. It is dosed at 50mg orally once daily to improve glycemic control in patients with type 2 diabetes as an adjunct to diet and exercise by inhibiting the DPP-4 enzyme and increasing incretin hormone levels. Common side effects include constipation, peripheral edema, headache, tremors, dizziness, decreased blood glucose, hyperhidrosis and urticaria. Nurses should monitor for side effects and exercise caution in patients with kidney disease or risk of foot ulcers.

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Chris Denver Bancale
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1K views2 pages

Drug Study Proglin

Proglin is an anti-diabetic drug classified as an islet enhancer and DPP-4 inhibitor. It is dosed at 50mg orally once daily to improve glycemic control in patients with type 2 diabetes as an adjunct to diet and exercise by inhibiting the DPP-4 enzyme and increasing incretin hormone levels. Common side effects include constipation, peripheral edema, headache, tremors, dizziness, decreased blood glucose, hyperhidrosis and urticaria. Nurses should monitor for side effects and exercise caution in patients with kidney disease or risk of foot ulcers.

Uploaded by

Chris Denver Bancale
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Name of Drug Classification Dose/Freq/Route Mechanism of Action Indication Side effect Nursing Implication

Proglin Anti-Diabetic 50mg/OD/PO Vildagliptin, a Adjunct to diet and Constipation, Peripheral Caution should be
member of the islet exercise to improve edema, Headache, Tremor, exercised in patients
enhancer class, is a glycemic control in dizziness, headache, with history of severe
potent and selective patients with type 2 Asthenia, Decreased blood kidney disease.
dipeptidyl-peptidase- diabetes mellitus ( glucose, Hyperhidrosis,
4(DPP-4) inhibitor T2DM) Urticaria, pancreatitis, It may cause dizziness or
that improves localized exfoliation or fatigue, do not drive a
glycemic control. blisters car or operate
The administration of machinery while taking
vildagliptin results in this medication.
rapid and complete
inhibition of DPP-4 Patient may develop
activity. In patients with increased risk of
with type 2 diabetes, foot ulcers and blistering
administration of of the skin; if it is so
vildagliptin led to consult with your
inhibition of DPP-4 doctor.
enzyme activity for a
24-hr period. Monitor liver function
Vildagliptin inhibition and blood sugar level
of DPP-4 results in regularly while taking
increased fasting and this medication.
postprandial
endogenous levels of Avoid excess dosage.
the incretin
hormones glucagon-
like peptide 1 (GLP-1)
and glucose
dependent
insulinotropic
polypeptide (GIP).

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