GENERIC NAME: MECHANISM OF ACTION: SIDE EFFECTS/ADVERSE NURSING

REACTION RESPONSIBILITY
Stimulates release of insulin frim beta cells of SIDE EFFECTS: BASELINE ASSESSMENT
pancreas, decrease glucose output from liver,
Glyburide increase insulin sensitivity at peripheral sites. Rare (less than 3%): • Check serum glucose level.
• Discuss lifestyle to determine
BRAND NAME: INDICATION: • Altered taste extent of learning, emotional
• To treat diabetes (type II) • Dizziness needs.
Diabeta • Drowsiness
• Weight gain
DRUG ILLUSTRATION: • Constipation INTERVENTION/EVALUATION
• Diarrhea
• Monitor serum glucose level,
• Heartburn
food intake.
• Nausea
• Assess hyperglycemia
• Vomiting
(polyuria, poly-
• Headache
phagia, polydipsia, nausea,
• Photosensitivity
vomiting, dim vision, fatigue,
• Peeling of skin
deep or rapid breathing).
• Pruritus
• Assess for hypoglycemia
• Rash
(cool/wet skin, tremors,
ADVERSE EFFECTS/TOXIC dizziness, anxiety, headache,
REACTIONS: tachycardia, perioral
numbness, hunger, diplopia);
• Overdose or insufficient food • Be alert to conditions that alter
intake may produce glucose requirements (fever,
hypoglycemia (esp. in pts with increased activity or
CLASSIFICATION: CONTRAINDICATION:
increased glucose demands). stress, trauma, surgical
• Hypertensivity to glyburide.
• Cholestatic jaundice procedure).
Sulfonylurea (Antidiabetic agent) • Diabetic ketoacidosis with or without
• Leukopenia
coma
 • Type 1 diabetes mellitus • Thrombocytopenia PATIENT/ FAMILY TEACHING
DOSAGE/FREQUENCY/ROUTE: • Concurrent use with bosentan. • Pancytopenia
• Agranulocytosis • Diet and exercise are principal
P.O 2.5 mg daily every morning • Aplastic or hemolytic anemia parts of treatment; do not skip
occur rarely. or delay meals.
• Avoid alcohol.
• Carry candy, sugar packets,
other quick-acting sugar
supplements for immediate
response to hypoglycemia.
• Check with physician
when glucose demands are
altered (fever, infection,
trauma, stress, heavy physical
activity).
• Avoid direct exposure to
sunlight. (At risk of diabetic
retinopathy. Diabetic patient
should protect their eyes from
the sun to avoid any additional
damage to the retina
occurring.)