DRUG STUDY

NAME OF THE DRUG MECHANISM OF DOSAGE AND SIDE EFFECTS NURSING RATIONALE
DRUG CLASSIFICATION ACTION ADMINISTRATION RESPONSIBILITIES
(DA)
Generic name:  Gastrointestinal Agents Synthetic prostaglandin NSAID-Induced Ulcer Gastrointestinal Advise patient to avoid Educating patient about drugs,
Misoprostol ; E1 analog that inhibits DA: Prophylaxis:  Diarrhea alcohol and foods that beverages, and foods that causes
basal and nocturnal 200 mcg PO q6hr with  Stomach pain may cause an increase in contraindication to the drug is
Brand name:  Prostaglandin; and gastric acid secretion food; may be decreased to  Nausea GI irritation. important to avoid problems in
Cytotec through direct 100 mcg q6hr if higher dose Gynecological drug administration.
 Endocrine. stimulation of is not tolerated; last dose to  Spotting
prostaglandin E1 be administered at bedtime.  Cramps Inform patient that Women of childbearing age must
receptors on parietal Should take therapy for misoprostol will cause be informed of this effect through
 Hypermenorrhea  
cells in the stomach. duration of therapy spontaneous abortion.  verbal and written information and
 Menstrual
Induction of Labor (Off- must use contraception throughout
disorder
label) drug treatment. If pregnancy is
 Dysmenorrhea   suspected, the woman should stop
DA: 25 mcg (1/4 of 100-mcg
oral tablet) intravaginally
Respiratory taking misoprostol and notify her
initially, then repeat at  Upper respiratory health care professional
intervals not to exceed q3-6hr tract infection immediately.
Not to be used in patients  Bronchitis
with previous cesarean  Bronchospasm Instruct patient to report Informing and instructing patient
delivery or major uterine  Dyspnea bothersome side effects. regarding to the possible side
surgery.  Pneumonia effects will lessen the anxiety and it
Postpartum Hemorrhage  epistaxis will help to have a good connection
(Off-label) Nervous for the possible action between
DA: Prophylaxis: 600 mcg system/Psychiatric patient and the nurse.
PO within 1 minute of  Anxiety
delivery Monitor for possible Clinical signs that may indicate an
 Change in appetite
Treatment: 800 mcg PO overdose. overdose are sedation, tremor,
 Depression
once; use caution if convulsions, dyspnea, abdominal
prophylactic dose already  Drowsiness
pain, diarrhea, fever, palpitations,
given and adverse effects  Dizziness
hypotension, or bradycardia.
present or observed  Thirst
Symptoms should be treated with
Give only in settings where Cardiovascular supportive therapy.
oxytocin not available.  Chest pain
Treatment of Incomplete  Edema
Abortion (Off-label)  Diaphoresis
DA: 600 mcg buccally once  Hypotension
 Hypertension
 Arrythmia