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Instructions: Reflect On The Topics That Were Previously Discussed. Write at Least Three (3) Things Per Topic

This document contains a worksheet summarizing key topics related to gene therapy. For gene therapy, it discusses defining it as a method of treating illness by altering gene expression or repairing mutated genes. For gene editing, it notes we can mend DNA and recreate missing sequences using techniques like ZFNs, TALENS, and CRISPR-Cas9. CRISPR-Cas9 is described as the most accurate and efficient new gene editing tool. Important events in gene therapy history include the first human gene transfer research in 1990 and CRISPR-Cas9 discovery and use from 2010-2013. Diseases discussed are Duchenne muscular dystrophy, leukemia, and Leber's congenital amaurosis.

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Guevarra Keith
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254 views2 pages

Instructions: Reflect On The Topics That Were Previously Discussed. Write at Least Three (3) Things Per Topic

This document contains a worksheet summarizing key topics related to gene therapy. For gene therapy, it discusses defining it as a method of treating illness by altering gene expression or repairing mutated genes. For gene editing, it notes we can mend DNA and recreate missing sequences using techniques like ZFNs, TALENS, and CRISPR-Cas9. CRISPR-Cas9 is described as the most accurate and efficient new gene editing tool. Important events in gene therapy history include the first human gene transfer research in 1990 and CRISPR-Cas9 discovery and use from 2010-2013. Diseases discussed are Duchenne muscular dystrophy, leukemia, and Leber's congenital amaurosis.

Uploaded by

Guevarra Keith
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
You are on page 1/ 2

GE1713

Topic Learnings
Name: ____________________________________ Section: ___________________ Date: _________

Instructions: Reflect on the topics that were previously discussed. Write at least three (3) things per topic
that you have learned. Answers must be written in complete sentences.

TOPIC LEARNINGS
Gene Therapy It is a method of treating illness in which the expressions of individual genes are altered,
or in which a mutated gene is repaired, in order to achieve the desired therapeutic effect.
(Definition and Principles) (Both a Definition and Some Guiding Principles)

Gene Editing We are able to mend two damaged strands of DNA using a technique called gene editing.
Additionally, it may be used to recreate a section of a chopped sequence that was previously
missing. There are now three established techniques for modifying genes: The use of ZFNs,
TALENS, and CRISPR-CAS9

CRISPR-Cas9 It is the most cutting-edge technology for modifying genes and has the most promising future.
In terms of accuracy, efficiency, and adaptability, this new editing tool is a significant
over its predecessor.
Is composed of several simple iterations of the same basic sequences

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GE1713

Topic Learnings
Name: ____________________________________ Section: ___________________ Date: _________

Instructions: Reflect on the topics that were previously discussed. Write at least three (3) things per topic
that you have learned. Answers must be written in complete sentences.

TOPIC LEARNINGS
Important Events in Gene The first human gene transfer research was conducted in 1990.
The first human gene transfer research was conducted in 1990.
Therapy 2010–2013: the years in which CRISPR-Cas9 was first discovered and put to use

Diseases Being Studied for A mutation in the dystrophin gene causes Duchenne muscular dystrophy, which affects both
the skeletal muscles and the cardiac muscles.
Gene Therapy
Acute lymphoblastic leukemia is a kind of blood cancer that causes the bone marrow to
produce an abnormally high number of immature lymphocytes, which in turn alters the
chemical makeup of the blood.

(Leber's Congenital Amaurosis) A hereditary condition of the retina that causes vision loss
starting in early childhood.

Issues and Concerns a lack of understanding regarding the therapy's effects over the long term, as well as the
fact that the profession is plagued with ethical problems.

The majority of gene therapies have a limited duration of effect, which requires patients to
undergo recurrent treatments.

If the inserted DNA is put in the wrong location, such as in a gene that suppresses
tumor formation, then a tumor may develop.

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