ANS DRUGS
SYMPATHOMIMETIC/ ADRENERGIC DRUGS
SYMPATHOMIMETIC DRUGS
DIRECT INDIRECT MIXED
NON-SELECTIVE SELECTIVE
NOREPINEPHRINE
EPINEPHRINE α β
DOPAMINE
α-1 α-2 β -NS β-1 β-2
PHENYLEPHRINE ISOPROTERENOL DOBUTAMINE
Anti-Glaucoma Anti-HTN
METHOXAMINE
APRACLONIDINE METHYLDOPA
SABA LABA Tocolytics
PROPYHEXEDRINE BRIMODINE CLONIDINE SALBUTAMOL/ SALMETEROL RITODRINE
TETRAHYDRAZOLINE GUANFACINE ALBUTEROL
(Ventolin) FORMOTEROL ISOXUPRINE
OXYMETAZOLINE GUANABENZ (Duvadilan,
TERBUTALINE BAMBUTEROL
(Bricanyl) (PO)
Isoxilan)
NAFAZOLINE
METAPROTERENOL INDACATEROL
PIRBUTEROL
RCB, RPh 2022
ANS DRUGS
SYMPATHOMIMETIC/ ADRENERGIC DRUGS
SYMPATHOMIMETIC DRUGS
DIRECT INDIRECT MIXED
EPHEDRINE
Releasers Reuptake Inhibitors
PHENYLPROPANOLAMINE
TYRAMINE COCAINE
MEPHENTERMINE AND
EPHEDRINE ATOMOXETINE METARAMINOL
AMPHETAMINE SIBUTRAMINE
METHAMPHETAMINE
MODAFINIL
METHYLPHENIDATE
PHENMETRAZINE
RCB, RPh 2022
ANS DRUGS
SYMPATHOLYTIC/ ANTI-ADRENERGIC DRUGS
SYMPATHOLYTIC DRUGS
CENTRAL PERIPHERAL DIRECT
α-2 AGONIST
Storage Exocytosis α Blockers Β Blockers
RESERPINE GUANETHIDINE
α- NS α-1 α-2
GUANEDREL
PHENOXYBENZAMINE YOHIMBINE
Anti-HTN For BPH
BRETYLIUM
PHENTOLAMINE PRAZOSIN ALFUZOSIN RAUWOLSCINE
TERAZOSIN TAMSULOSIN
DOXAZOSIN
RCB, RPh 2022
ANS DRUGS
SYMPATHOLYTIC/ ANTI-ADRENERGIC DRUGS
β Blockers
β- NS β-1 ADDT’L MOA
NADOLOL CELIPROLOL
Membrane-
ISA stabilizing Action
With Vasodilation
BISOPROLOL,
SOTALOL
BETAXALOL CARTEOLOL, PROPRANOLOL, Alpha-1 Blockade
CELIPROLOL PINDOLOL Carvedilol, Labetalol
TIMOLOL ESMOLOL
LABETALOL ACEBUTOLOL
Inc. NO2: Nebivolol
ACEBUTALOL,
PROPRANOLOL ATENOLOL
ACEBUTALOL LABETALOL
METOPROLOL
PINDOLOL METOPROLOL
PENBUTANOL
RCB, RPh 2022
ANS DRUGS
PARASYMPATHOMIMETIC/ CHOLINERGIC DRUGS
CHOLINOMIMETIC DRUGS
DIRECT INDIRECT
Choline
Alkaloids Reversible Irreversible CNS-acting
Esters
Non-sel: TACRLINE
METHACHOLINE NS M-sel. N-sel. Aminoalcohol Carbamates Organophosphate
DONEZEPIL
M-sel.: ARECHOLINE MUSCARINE NICOTINE
EDROPHONIUM -STIGMINES Pesticide:
BETHACHOLINE MALATHION,
PILOCARPINE LOBELINE GALANTAMINE
AMBENOMIUM, PARATHION
DEMECARIUM
VARENICILINE Nerve Gases: RIVASTIGMINE
SOMAN,
TABBUN,
SARIN
Only Clinically Useful:
ECHOTHIOPHATE
RCB, RPh 2022
ANS DRUGS
PARASYMPATHOLYTIC/ ANTICHOLINERGIC DRUGS
CHOLINOLYTIC DRUGS
Antimuscarinics Antinicotinics
ATROPINE MISCELLANEOUS
GIT and Urinary
CNS Eyes Bronchi Gastric Gland
Bladder
TRIHEXYPHENIDYL HOMATOTROPINE PIRENZEPINE METHSCOPOLAMINE
SAMA LAMA
BENZTROPINE ANISTROPINE TELENZEPINE GLYCOPYRROLATE
IPRATROPIUM TIOTROPIUM
BIPERIDEN CYCLOPENTOLATE
OXYTROPIUM GLYCOPYRRONIUM HYOSCINE-N-BUTYL
SCOPOLAMINE BROMIDE (BUSCOPAN)
UMECLINIDIUM
DICYCLOVERINE
OXYBUTININ
SCOPOLAMINE
RCB, RPh 2022
ANS DRUGS
PARASYMPATHOLYTIC/ ANTICHOLINERGIC DRUGS
CHOLINOLYTIC DRUGS
Antimuscarinics Antinicotinics
Nn Nm
HEXAMETHONIUM
Depolarizing Non-Depolarizing
MECAMYLAMINE
SUCCINYLCHOLINE
TRIMETHAPHAN Isoquinoline Steroidal
ATRACURIUM PANCURONIUM
TUBUCURARINE ROCURONIUM
RCB, RPh 2022
H1 ANTIHISTAMINES
First Generation Second Generation
Ethanolamines Ethylenediamines Piperazine Alkylamines Phenothiazine Piperidine Piperazine Piperidine Newer Agents
DIPHENHYDRAMINE PROMETHAZINE
PYRILAMINE HYDROXYZINE CHLORPHENAMINE CYPROHPETADINE CETIRIZINE LORATADINE BILASTIN (Bilaxten)
(Phenergan)
DIMENHYDRINATE TRIPENNAMINE MECLIZINE BROMPHENIRAMINE LEVOCETIRIZINE DESLORATADINE EBASTINE with
Betamethasone (Co-
CARBINOXAMINE alleva)
FEXOFENADINE
DOXYLAMINE (Unison)
RCB, RPh 2022
DRUGS FOR COAGULATION DISORDERS
ANTITHROMBOTICS
Anticoagulants Antiplatelets
Direct Indirect Destroys clotting factors which
Inhibits IIa
activate prothrombin (II)
HIRUDIN Forms an active
Parenteral complex with AT-III Oral
LIPIRUDIN APIXABAN
(DOC: Heparin Induced
Thrombocytopenia)
Inhibits Xa
UNFRACTIONATED RIVAROXABAN
BEVALURIDIN HEPARIN/ REGULAR/ LMW HEPARIN
HIGH MW HEPARIN WARFARIN Inhibits hepatic synthesis of
Vit K.-dep factors (10, 9, 7, 2)
ARGATROBAN
ENOXAPARIN
DABIGATRAN
(Pradaxa) –PO DALTEPARIN
TINZAPARIN
FONDAPARINUX
DANAPROID
RCB, RPh 2022
DRUGS FOR COAGULATION DISORDERS
ANTITHROMBOTICS
Anticoagulant Antiplatelets
Phosphodiesterase
TXA2 Synthesis Inhibitor ADP Inhibitors GPIIa/GPIIb Inhibitors
Inhibitors
DIPYRIMADOLE
ASPIRIN EPTIFIBATIDE
Irreversible (PERSANTIN)
Reversible
(Thienopyridines)
CILOSTAZOL (PLETAAL) ABCIXIMAB
TICLOPIDINE TICAGRELOR
TIROFIBAN
CLOPIDOGREL
RCB, RPh 2022
