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Pharmaceutical Organic Chemistry-Iii: Instructions To Candidates

This document contains instructions and questions for a pharmaceutical organic chemistry exam. It is divided into three sections: Section A contains 10 short answer questions worth 2 marks each, Section B contains 3 long answer questions worth 10 marks each where students must answer 2, and Section C contains 9 short answer questions worth 5 marks each where students must answer 7. The questions cover topics like optical isomerism, conformational isomerism, synthesis and reactions of imidazole, purine, acridine and indole, enantiomerism and diastereomerism, asymmetric synthesis, optical activity, Schmidt and Clemmensen rearrangements, aromaticity of thiophene and furan, oxidation reactions, and structures of heterocyclic compounds

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Nitish Pathania
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88 views2 pages

Pharmaceutical Organic Chemistry-Iii: Instructions To Candidates

This document contains instructions and questions for a pharmaceutical organic chemistry exam. It is divided into three sections: Section A contains 10 short answer questions worth 2 marks each, Section B contains 3 long answer questions worth 10 marks each where students must answer 2, and Section C contains 9 short answer questions worth 5 marks each where students must answer 7. The questions cover topics like optical isomerism, conformational isomerism, synthesis and reactions of imidazole, purine, acridine and indole, enantiomerism and diastereomerism, asymmetric synthesis, optical activity, Schmidt and Clemmensen rearrangements, aromaticity of thiophene and furan, oxidation reactions, and structures of heterocyclic compounds

Uploaded by

Nitish Pathania
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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Roll No. Total No.

of Pages : 02
Total No. of Questions : 13
B.Pharma (2017 Batch) (Sem.-4)
PHARMACEUTICAL ORGANIC CHEMISTRY-III
Subject Code : BP-401T
M.Code : 75843
Time : 3 Hrs. Max. Marks : 75

INSTRUCTIONS TO CANDIDATES :
1. SECTION-A is COMPULSORY consisting of TEN questions carrying T WO marks
each.
2. SECTION-B contains T HREE questions carrying T EN marks each and student
has to attempt any T WO questions.
3. SECTION-C contains NINE questions carrying FIVE marks each and student has
to attempt any SEVEN questions.

SECTION-A

1. Write short notes on :

(a) Define Optical activity.

(b) What are meso compounds? Give one example.

(c) What is resolution of racemic mixture?

(d) Draw Eclipsed and Staggered conformation of ethane. Which is more stable?

(e) Define Geometric Isomers giving suitable example.

(f) What are stereospecific reactions?

(g) Write chemical structure with numbering of quinoline.

(h) Write structures of pyridine and pyrimidine.

(i) What functional groups does sodium borohydride reduce?

(j) What are chiral and achiral molecules?

1 M-75843 (S29)-107
SECTION-B

2. Discuss in detail DL system and RS system of nomenclature of optical isomers.

3. Comment on “conformational isomerism in n-Butane and cyclohexane”.

4. Write the synthesis, reactions and medicinal uses of imidazole, purine, acridine and
indole.

SECTION-C

5. Write in detail about enantiomerism and diastereomerism.

6. Discuss in detail about partial and absolute asymmetric synthesis.

7. Give an account on optical activity due to chiral axis.

8. Discuss mechanism as well as synthetic importance of Schmidt rearrangement.

9. Write mechanism involved behind Clemmensen reduction and Birch reduction.

10. Write about relative aromaticity and reactivity of thiophene and furan.

11. Explain Oppenauer-oxidation and Dakin reaction.

12. Discuss structure and uses of oxazole, pyrazole and thiazole.

13. Give brief note on elements of symmetry.

NOTE : Disclosure of Identity by writing Mobile No. or Marking of passing request on any
paper of Answer Sheet will lead to UMC against the Student.

2 M-75843 (S29)-107

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