Recluced pasiticle Size aw DLvo Thy > Used trexplain slabiliy ofabmead” Used to wlan eres moveranlj Colloicly The arqeunt af vericle ruedid to produce pousiaksUis 4 duncted by 3 Flow point ¥ xB *Formulation of Suspension Floceulate, Suspend Probechive |bJeHe H ive] Oxgane — gata | RE Pla Pg omar et SLS, lat get qe Ty 2 ge oe Taeens, [Lnergant apd: Giblatin, PAM! i |enreie a ft Seeded Span, * “cial Al(oh), | Nala gun] og ae Matlag| psi Ke . casbordax p Synthetics | Gllalese iy -| Selb ee Coitbomer, Callaligh WiVAKveL P Gtelalin, ty Benen | eee 80, Seeldit eg, alginole Flavousés Polyecrceharicle ae Spent Tale, te, upc Teta potential of Saspensiog Zs helpful fo find Buf ie es glaliy persion K Stoke's law >? Ral Of Secinnsrta tog ty wrprensed AES i By | K Selimantaticg Rm CNlo Sedma token | A Voltwra = © CCompltt SecPrrealatton HK stokes law applicabk to di ploccala ted Systen— | phew particle soy (nbpedely ae / % Defloculated Supenion shows —I Newtonian fled 5K Floceulated stspension Shoos —9 Alon-Alewhonian Floo 3K The prolarning — tine uupension 4 prpasud by g seatad va sy Alteud pH Prechitalicn 4 K bolich of the voct ng Euspenst ns — Sle *K een ving | polaprees a —d Carbomer agent usd in pountera}K “Zeta potential —> = 7 ~ 7 \ D Tremtaurtirunt of eta polenta) gives Chase on pasiticles, D Faction Wyaluagen phesphaXe i disalnd — PSH Y 4 Superson Te del TR appauunt ela poteafia| intially 4 > Negative Cmination 4 charge ny the poukele kt 7 Euspension Und 3 Zeta” matey uf 3) K Dilule p05 bo 2x slid - Stoker law pty x Gncentratien 3 FH lo% Gulid ~ Hindsiarce occeery GPAT DISCUSSION CENTER Online Test Series ie LAKSHYA GPAT ACHIEVE GPAT 42+28+30 3ori2+18 GPAT - 2020 09, ONLINE TEST SERIES 0, Sues aes 2500 / ENROLL NOW 1500HE Not Used fer par erar . Cee et soluble material arse. 1 Hatin Cet“: NHyCL , 2) o Higly eFfloescent cause 5 softness of shelf THigly Mela uescent -bofitleness of shel) Used to ~ > Mask the taste Mask the odoug GELATIN §— Helesogeneots uct, deafved by Hydielytic = extraction animal _cellagen TYPES OF GIE LATIN Type SOURCE | PROCESSING __[TS0-ELECTRIC POINT. Type-a [Rek skPy [Acid Psocessed PH >9 “Type- B | Bones Alkal? Processed PH - WF * HARD GELATIN CapsuLce (Herc) Components of Hae Shell gee oF * Capsule shel) - Gidlatin! [55 as * Dyes - Trdige , oe tt vo 83°F = 218 ° Opacities _ Try T Les ° = 3 12-3 ® Plastictzes — Serbito)) , 3 © Pall Bhs 5 Is" 43 i | ROU Pa avatfe - Me hyl_poxaben Lys % ons Iso Propyl pasaben (4) s Weg ols loo FM "eta of fran of empty Hac shell- 2 Dip pi a vsed) (thickness depend on Speed} tin TERPS DESCRIPTION 1 > Dippin: “of pin = 22°C, Sof? temp = ¢ f Apeee of Dipping = 12 See. er poconing! “| Pins one rotated . Aa Tee {oy eee ef Ory ah cehumietlPeatin, ripping Boonze fauss- = +, 2 see a 4 Biroming By stationary knfves - Tefning | Cap & Body ase fofned i Po Ushing By Polymer -Hie Paveess of filled HOC ~ | HE Method of CleanPng~ x Preparing the -formulah®n fel hing. c 7 —tt a ee be Pan fotishing —AL cel a [x Selection ef the size of capsule| FBI, coalley eae sate lx Poopes mnffeefing & Blenclin le Cloth dustthna . pe ffltfog the Capsule shells. | px Beushfn lx Capsule sealfng & shortfng.| | Eaweka KEA Machine. Ie Cleanfng &k pollhPnag [X Sciclenades Pm. _60 og mi Cv He Capsule Filling Machine. _| |ae Capsule We&hing Machin Hoflijea_k Kasg —> Bulk pousdea | [sWerteap —i280 Fey = Bulk pevsdes le Rotowefah Fasmatic ——> Bulk powodea [> ConditHen for Capsule. | Macofas ——> Bulk povsder Storage = too°F (35°C) EU Uy ——> Pellet, granales | | Area temp. = 22%c (Proce Zanast > Powder , pellet pranules Humidity = 30 — 4s [Osaka —> Based on yibration pain. | | Moisture MG, —> Continuous Ue of Contend = 12-16 [ RetoPis ee oe : ictzeg = 1 to. Retoffl) >», tee 7 eee : Plasticizes = 1:0-4 3 GELATIN CAPSULE i- on LE = lo Grelatin Bloom si th = Isp - 120°, Viscosity = 25-US oni Lfpoise| Taon content = NMT 4S ppm __ le Plasticizers ~ sorbitol , glycerin PEG; [4ebsin § Plesitiet] os “1 20.8 | jo Preservatives, — 0.2 “/, Methy( parabon * Prepyl pasaben =F atag © Opacifieas — Tio, - @ Fumosfe acid 1%. 1 acid soubilty KS aldehyde | € sserciol of) — 2 7 a Formalin ~Retards dissolution ef gelatin - Cooting matesfal - sales) , CaP , shellac #50, = ois ‘h of gelatfy (Prevent SecomposPhonAPSULE “i... Evaluah'o a dnv Sealy saute. Weitett Vastation oer ee Uni-foom Ply Avg - wt: of caps| 7s olevfatien a less than sop "f ro %, Pd er mo 5%, test pass iP, all 30 Zap- Sule ase ustth ty 4S -125% yonge » NLT QF of 30 ase within 85-115 %, E & Aissolution test = er e fotating Basket type - (ez Pritegraction test | (a Stabiltkp test i >For Hee We Tiana. shell integrity test * Fer SC = min. Sete fnat en of self life. Note 3— HK So. Spet —sfte at ushich capsule Ue next to . Fe the. tray or against anotheg rureapoule, [7 Seottng A 7 ne hi dao, tmiclity (60 1) ee sire I Fo: = Unfilled capsule «RILIZATION (<....... Precas elesignated Lo prodice co alrile tote, * Some basic terms 1 2 SkeriWhy © Cendlifion Foo from Living organisms, (atetc Y D-valie (Decimal Reduction Vine) Fi my er ‘Sloje weguird | chink popu o de | | Fy, Pee seh re lation +, elicbls one | 1) Z-value (Therma cletfuction Value)!~ de oe | reguired for 1 Mog pelle Fin Diem” | DFM Lime Notes ct pectic 2 | | (eaweley aso F /19y | J els ow Apert, 9 Holding Time! Time required 2) Thermal Death Timet (ToT) ? all erganismy in SE Stevilization Meth dt + oe Skilizahion by HEAT : neccled - ein 6 paubtin fx killing ee nh Bis organismr Aherfes? Lime necded Lo kill ee Mcrobicd maspesion, Dry heat Skyilrafion ? le fos oils, petroleum getliey Aaleum pousder, glass ke metallic Apparatus. Pi ont mer resicfonk te eby Rat Sean meu heck. ® BF uted I fae reps, Needles , cal; cp Mins 2s metal apabulas Bunsen flame to Lhe seoface for & seeencht. ®_Hot air oven! 180 mind at 180°C 45 rrinulis at 260°C. MoA! Destruction redid int of beef Kit Tr an | Oxidation eect «fot Jasp wares be oily aqn ag” oo 2_Moist heat Sfrilizafion! MoA : 5 Regulation aS proteins Used fer: Porous ath buch as cotton wool, Hoppers, yr, Cloth wray ers y bubs Kills dormant, reti dont Apores alto“ No speria! apparalu reguoel, (4) Heating with a bactevicide > Backrici de are more effeitile at Noh kimp fan low Hap} > offical in BP. he eenlss heating a4 90 100°¢ 1 3 tt ms Fox ingections! Chlorocresef ory wly Phanylmnercuric acetate ©,002 Arh Bemralleonium Chloride 804. Yu) Thiomersal sory (5) Pasteurization : olevised Pasteur. > OF only reduces Le viable Counk by 97 +0 999. but does rot kill spores: > applied +e milk tn dairies, (6) Dry heat abo A507, backrial aj passin an exprmely heckled fernace can be AbAlised in) 0.4= Ob rec, af Q9%C % Nole: More uses UV radiation 1D Fnactivafe viruses & bacteria in Vaccine production + D alse used fov. irradiation Incomin and Jor inkrnal aiy the “alerile filling arvas anh bioke, t nD prevent Crem InfecH. y Des eg ates ee 3h hslptnls (BJ Sterilization by Racliation ! = Also known as “Cold Sprilization ', Mo» inferfirence in a mefabeliim q We cell, W_Othaviolet light ! > 2539 A possess greatut achvile in dubeying me jy reduction gy aly borne” contami ~nation L mdintenane J aseptic areas ke remy , Mop. UV Light absorbed nucleic acs 4 Ue cell there tt clos Lhe greeter darege, Uses to olastroy Ua virutu Romelogous serum qaundiee in (2). Sonizing Racliation ! Prokaene TO toen Fs patsy tem cheagedl penficlen In Aireetlys 1 gamina rays 3 Ha hight penetrating pomen. Moa > des mmicrebes Adeppi yecluction A a vrerull fetal dations « Uses tpreevation 4 frds. D Ingechion preduch ¢ antibiokies Like” hemry)panicillin phimytin AulphSTERILIZATION (72... * Nok: “ont fer meammerad of radiation dose t D Roertgen (*) 9 fundamental unit fr rediahion dose, 95 dlefined In forma qf Bbc number of jonsrahions Produced per unit vide Goaive Bovad. — Anctley unit which oeprsenli an energy. abseptin Y 160 erga per gram J malriak, (¢]. Speriliration by Filfrahen | — ___ A} > Wed for bhrilization q heat-labile athens, | OK offical in OP for akerilization q eertain Injection acl%, Effaent fillen ! Should be able to ofan Servatia maresscens. Av. por diamdve 2 O,9s Nm ov late. Commonly ured fillen art: > porcelain Filfers , diatomaceous earth #lJen, Qh asbesfos pad filters, Sintered gla fi}, mumbrene filktn ho Uitredltn, Moa: removal { miersher (Phyrical) frm Sample [DB]. Chemical Processes of Serilization (Gaseous Uoiliahn} (oO) Ethylina Oxiol Pie Pe \ : ay = Simplest cyclic ether ~ Nghby inflammable 7 may be explosive at cme 73y, in or > made arate by mixing with inet geter Or ek> Pleasant smelling buk Sod? ee eahian net oe R fonic gn Yoon & fae Cente > genera probeplasmic Oxidant > Inpitant & pungent I > kil al beckwia, Ine lading Ydisinfeckrn noly pores, vapidly, | |i) prerervation forks frm a) ” ; | fps doth bole cee ert *| b hrage, Uses’ X- £90 } © pi- Propiolachne (a7) ‘ ‘| + Ng bacfericidad | > conc wel~ Gry] tite w | | les, Uses ; 1D) fas rooms , Chamber, in ") Aighby viruciclal bef Cardine genic fo animals . _ to Study SMART (ammo Mobile Ys Applicaton