Al-Quds University جــــــــــــــامعــــــــــــــة
القـــــــــــــــــــــدس
Faculty of Health Professions كليـــــــــــة
المهــــــــــــــن
الصحيــــــــــــــة
Medical Laboratory Sciences العلــــــوم دائـــــرة
Department الطبيـــــــة المخبريــــــة
Clinical Chemistry
1. Which of the following additives should be used for the collection of a sample for
blood gas analysis?
A. Sodium citrate
B. EDTA
C. Sodium oxalate
D. Heparin
2. The recommended storage temperature for the preservation of activity for MOST
enzymes is:
A. 0 oC
B. 4 oC
C. 25 oC
D. 37 oC
3. Which one of the following cardiac biomarkers could detect a recent reinfarction?
A. Troponin I (TnI)
B. Troponin T (TnT)
C. Lactate dehydrogenase (LD)
D. Creatine kinase MB (CK-MB)
4. TIBC (total iron-binding capacity) is an indirect measurement of which of the
following:
A. Ferritin
B. Hemoglobin
C. Ceruloplasmin
D. Transferrin
5. A 29-year old pregnant woman had an outpatient glucose tolerance test. The
patient was given a 100-gram dose of glucose and the following values were
obtained:
Fasting = 110 mg/dL 1 hr. = 188 mg/dL
2 hr. = 175 mg/dL
3 hr. = 143 mg/dL
The MOST likely interpretation of this glucose tolerance would be:
A. Insulin dependent diabetes mellitus (IDDM)
B. Non-insulin dependent diabetes mellitus (NIDDM)
C. Gestational diabetes mellitus (GDM)
D. Normal glucose tolerance test
6. A patient has a fasting plasma glucose (FPG) performed at an outpatient
laboratory. He has fasted as instructed.
FPG: 135 mg/dL
What does this result indicate and what, if any, further action is recommended by the
ADA?
A. Elevated FPG; needs further evaluation by a repeat or alternative test
B. Decreased FPG; a repeat of the test is recommended in one year
C. Sufficient documentation for diagnosis of diabetes
D. Needs no further evaluation; this is a normal FPG
7. A deficiency in which of these vitamins leads to increased clotting time and may
result in hemorrhagic disease?
A. Riboflavin
B. Pyridoxine
C. Vitamin C
D. Vitamin K
8. Which of the following lipoproteins will form a creamy layer at the top of stored,
non-fasting plasma specimens?
A. High-density lipoproteins
B. Low-density lipoproteins
C. Chylomicrons
D. Very low-density lipoproteins
9. Most common methods for measuring bilirubin are based on the reaction of
bilirubin with:
A. Methyl alcohol
B. Neural salts
C. Bilirubin oxidase
D. Diazo reagent
10. What additional fraction would be seen if plasma rather than serum was subjected
to electrophoresis:
A. Alpha-1 antitrypsin
B. Alpha-2 macroglobulin
C. Fibrinogen
D. Gamma globulins
11. What is the largest constituent of plasma nonprotein nitrogen:
A. Ammonia
B. Creatinine
C. Ketones
D. Urea
12. What condition is indicated by the following arterial blood gas results?
Bicarbonate = 32 mmol/L (Normal = 22 - 29 mmol/L)
pCO2 = 65 mm Hg (Normal = 35 - 45 mmHg)
pH = 7.28 (normal = 7.35 - 7.45)
A. Healthy condition
B. Uncompensated metabolic acidosis
C. Compensated metabolic acidosis
D. Uncompensated respiratory acidosis
13. All of the following are components of a basic single beam spectrophotometer,
except:
A. Beam splitter
B. Cuvette
C. Prism
D. Light source
14. Which of the following would be considered a normal cerebrospinal fluid glucose
level if the serum glucose is 70 mg/dL?
A. About 100 mg/dL
B. About 45 mg/dL
C. About 60 mg/dL
D. About 70 mg/dL
15. A routine laboratory workup is ordered for an outpatient. The patient's lipid
results are as follows:
Total cholesterol = 295 mg/dL
HDL = 30 mg/dL
Triglycerides = 200 mg/dL
What is the LDL cholesterol level for this patient?
A. 225 mg/dL
B. 65 mg/dL
C. 365 mg/dL
D. 255 mg/dL
16. Which of the following conditions would make a sample unsuitable for lactic acid
testing?
A. Movement of hand or arm during specimen collection.
B. Received in the laboratory on ice.
C. Centrifuged in a refrigerated centrifuge.
D. Specimen centrifuged and plasma separated from cells less than 15 minutes after
collection.
17. When three tubes of cerebrospinal fluid are received in the laboratory they should
be distributed to the various laboratory sections as follows:
A. #1 Hematology, #2 Chemistry, #3 Microbiology
B. #1 Chemistry, #2 Microbiology, #3 Hematology
C. #1 Microbiology, #2 Hematology, #3 Chemistry
D. #1 Chemistry, #2 Hematology, #3 Microbiology
18. Tumor markers are especially valuable when used to:
A. Rule out cancer
B. Screen the general population for cancer
C. Monitor response to cancer therapy
D. Confirm other assays
19. When evaluating a 2-hour glucose tolerance test report performed on a pregnant
woman, which of the following results is considered NORMAL (within range for
this test)?
A. A 2-hour glucose level is less than 140 mg/dL
B. A 2-hour glucose level is less than 10 mg/dL
C. A 2-hour glucose level greater than 153 mg/dL
D. No change in glucose values during 2-hour glucose tolerance test
20. Which of the following is the most common technique that is used by clinical
laboratories for therapeutic drug monitoring?
A. Immunoassay
B. Electrophoresis
C. Atomic absorption
D. Ion selective electrode voltimetry
21. An electrolyte panel (lytes, chem-4) consists of:
A. Potassium, Sodium, Chloride, Carbon dioxide (in form of bicarbonate)
B. Potassium, Sodium, Chloride, Glucose
C. Potassium, Sodium, Chloride, Creatinine
D. Potassium, Sodium, Chloride, BUN
22. Which of the following tests would be used in the assessment of glomerular
filtration?
A. 24 hour urine protein
B. Creatinine clearance
C. PSP test
D. Urea
23. Sodium fluoride is an excellent preservative for collecting glucose specimens
because:
A. Prevents interference with other substances
B. Inhibits glycolysis
C. Enhances chemical reactions
D. Inhibits certain clotting factors
