Name: Princess Arielle B.

Kintanar, SN Date: November, 25

Year and Section: BSN3G

Worksheet 2
NCM 112 Lecture

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

Name of Drug Mechanism of Action Common Side Effects Nursing Precautions

(5 pts) (5 pts) (5 pts)

Thought to produce analgesia and exert its  Agitation  Contraindicated in individuals

1. Aspirin anti-inflammatory effect by inhibiting  Confusion hypersenstive to the drug, NSAID
prostaglandin and other substances that  Dizziness induced sensitivity, and bleeding
sensitize pain receptors. It may relieve fevr  Headache disorders.
through central action in the hypothelamic  Hypotension  Avoid use in patients with severe
heat regulating center. IN low doses, it also  Nausea and Vomiting hepatic or renal impairment, G6PD
interfere with clotting by keeping platelet-  Anemia patients or history of peptic ulcer
aggregating substances from forming.  Hypersensitivity reaction  Caution in children, pregnant and
lactating women.
May inhibit prostaglandin systhesis, to  Dizziness  Hypersensitivity to drug
2. Ibuprofen produce anti-inflammatory, analgesic, and  Headache  History of asthma or other allergic
antipyretic effects.  Nervousness reaction to NSAIDs
 Abdominal Pain  Increase risk of stroke or heart
 Constipation attack
 Nausea and Vomiting  Contraindicated for the treatment
 Cough of perioperative pain after CABG
 Anemia surgery
 Edema  Contraindicated for pregnant or
lactating mothers.
 May inhibit prostaglandin systhesis, to  Dizziness  Contraindicated in patients
3. naproxen produce anti-inflammatory, analgesic, and  Drowsiness hypersentive to drug and in those
antipyretic effects.  Headache with syndrome of aspirin sensitive
 Vertigo asthma, rhinitis and nasal polyps.
 Insomia  Caution, can cause skin reaction.
 Fever  Use caustionsly in adults and in
 Constipation patients with HTN, Hyperkalemia,
 Diarrhea renal disease, CV disease, GI
 Nausea disorder, hepatic disease or
 Edema history of peptic ulcer.
 Palpitations  Contraindicated for pregnant or
lactating mothers.
Reversibly inhibits cyclooxygenase 1 and 2  Dizziness  Contraindicated for treatment of
4. diclofenac enzyme which decreases proinflammatory  Drowsiness pain after CABG surgery.
process. Has analgesic, anti-inflammatory,  Headache  Contraindicated for patients with
and antipyretic properties.  Edema drug hypersensitivity.
 Sinusitis  Increase risk of serious CV
 Abdominal Pain thrombotic events
 Constipation  Caution in patients with history of
 Diarrhea peptic ulcer disease, hepatic
 Nausea and Vomiting dysfunction, cardiac disease, HTN,
 Osteoarthritis Fluid retention, or impaired renal
 Bruising function.
 Hypersensitivity reactions  Contraindicated for pregnant or
lactating mothers.
Inhibit prostaglandin sysnthesis, impending  Dizziness  Contraindicated to patients
5. celexocib cyclooxygenase-2, to produce anti-  Headache hypersentive to drug,
inflammatory, analgesic, and antipyretic  Insomia sulfonamides, aspirin, or other
effects  Fever NSAIDs.
 Rhinitis  Avoid use with patients with
 Diarrhea recent MI.
 Back pain  Contraindicated with patients with
 Cough renal and hepatic impairment.
 Hypersensitivity reaction  Use cautionsly with patients with
history of ulcer, GI Bleeding,
advanced renal disease,
dehydration, anaemia,
symptomatic liver disease, HTN,
edema, HF, asthma, or in poor
CYP2 metabolizers.
 Contraindicated for pregnant or
lactating mothers.