Systematic Review October2024
Systematic Review October2024
24 October 2024
2
Schedule
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Learning goals
▪ You can mention different review types, each having its own characteristics,
strengths and weaknesses
7
Many types of review
Critical Review Literature Review
Mapping Review Rapid Review
Scoping Review Systematic Review
Umbrella Review State-of-the-Art Review
Mixed methods Realist Review
and more
Differences in:
✓Searching
✓Quality assessment
✓Synthesis: narrative, tabular, graphical
✓Analysis: conceptual, chronological, thematic, include
recommendations for future research
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Comparing review types
9
Source: Cornell University
10
Additional information on review types
https://onlinelibrary.wiley.com/
doi/epdf/10.1111/j.1471-
1842.2009.00848.x
11
Systematic review versus literature review
Inclusion & Exclusion criteria Not specified Criteria stated before review is
conducted
Search strategy Not explicitly stated Comprehensive search
conducted in a systematic
way. Reported, including list of
sources.
Systematic review versus literature review
Results and data synthesis Conclusions are more Clear summaries based on
qualitative and may not be high quality evidence.
based on study quality Recommendations for practice
or to address knowledge gaps
16
Content overlap of databases in nursing and health sciences
17
Sources for finding literature in a systematic review
▪ Bibliographic databases
▪ Supplemented by:
● Grey literature
● Registries
● Reference lists, citations, related articles
● Table of contents of specific journals
● Preprint servers, e.g. ArXiv, SocArXiv
● AI tools
● Ask an expert
● Google Scholar
●…
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19
How to be systematic in these supplemental searches?
Try Evaluate
Improve
21
22
23
Systematic review
▪ Systematic
▪ Thorough
▪ Transparent
▪ Repeatable
▪ Unbiased
http://en.wikipedia.org/wiki/Systematic_review
Percentage of initially identified papers included in a systematic
review
35
73% Lowest number of initially identified publications: 30
Percentage of systematic reviews
30
Highest number of initially identified publications: 115,715
25
20
“Indeed, before the subject could be set in a clear and proper light, it
was necessary to remove a great deal of rubbish”
15 (James Lind, 1747, first controlled clinical trial)
10
0
1-2
2-3
3-4
4-5
5-6
6-7
7-8
8-9
<1
9-10
18-19
10-11
11-12
12-13
13-14
14-15
15-16
16-17
17-18
19-20
20-25
25-30
30-35
35-40
40-45
45-50
50-55
55-60
60-65
65-70
70-75
75-80
25
Numbers of studies included in systematic reviews at WUR
25
60%
Percentage of systematic reviews
20
15
10
26
Steps in a systematic review
http://en.wikipedia.org/wiki/Systematic_review
Formulation of review question
https://www.dreamstime.com/
- Specific
- Appropriate
- Manageable
- Relevant to the outcomes
30
Tools to identify key elements for your review question
P (population/patient/problem studied)
I (intervention or treatment)
C (comparison/alternative, control)
O (outcome/expected result)
(S, T, C) (study type, time frame, context)
31
Example of PICO
32
Tools to identify key elements for your review question
S (setting)(where)
P (population or perspective)(for whom)
I (intervention)(what)
C (comparison) (what else)
E (evaluation) (what result)
https://libguides.nus.edu.sg/
33
Example of SPICE
https://libguides.nus.edu.sg/
I behavioural therapy
C none
E coping skills
34
Tools to identify key elements for your review question
S (sample)
P (phenomenon of ...
I (... interest)
D (design)(e.g. questionnaire, focus group, interviews)
E (evaluation)
R (research type)(e.g. qualitative, mixed method)
https://libguides.hull.ac.uk/
35
Example of SPIDER
https://libguides.hull.ac.uk/
E evaluation experiences
R research type qualitative
36
Scoping
Skorupskas on Unsplash
Photo by Paul
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Development of protocol
Define:
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Decide on the inclusion/exclusion criteria
Exclude on:
Date Language
Geographic location Population
Intervention Type of study
Topic Study design
Setting Type of document ....
Mammals other than marine, livestock Marine species, livestock, other domestic species
and other domestic species
https://www.jclinepi.com/article/S0895-4356(21)00073-1/pdf
43
44
Register systematic review protocol
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Use available resources - centres
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Available in WUR library
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Available in WUR library
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Use available resources – manuals/tutorials
▪ SYRCLE
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Exercise 1: review question and aim
▪ Write down
● your review question
● aim of your Systematic Review
▪ Do some scoping.
For more info: ‘Orientation on topic’ and ‘Focus your topic’ in the module
‘Orientate on a topic and prepare a search’ on the library’s webpage with e-
learning modules.
Performing a systematic search: Selecting the right resources
Learning goal
• No quality check
• No systematic search
• Reproducible
• Quality check
• Systematic search
Types of databases
Subject specific
Sensitivity of models on leaching of pesticides to ground water
unique records 60 73 48 59
Off-campus access
https://www.wur.nl/en/Library/FAQ-Library/FAQ-display/Off-
campus-access-to-online-resources.htm
Let’s practice!
Exercise: Find and open the databases CAB Abstracts & Zoological record
Grey literature
Grey literature
67
Learning goals
▪ What source types are you looking for? (e.g. peer reviewed articles, certain
types of grey literature, etc.)
For more info: ‘Choose your resources’ in the module ‘Orientate on a topic and
prepare a search’ on the library’s webpage with e-learning modules.
Performing a systematic search
Learning goals
▪ You can select the most fitting search strategy for a certain purpose
72
1. Simple search - quick and dirty
▪ Orientation on a topic
Steps for a
systematic search 5. Execute search
Mammal
Loxodonta
Africana
Systematic search
▪ Find:
● Synonyms/antonyms
● Examples of the thing (e.g. dairy -> milk)
● Singular/plural
● Word variations (farm, farmer, farming)
● UK/US spelling
● Scientific names for organisms
Wikipedia
CC BY-SA 3.0
artificial night lighting behaviour Parus major
.... ....
TITLE-ABS-KEY(africa* or “africa south of the sahara*” or atlas or
igboland or maghreb or maghrib or maputaland or mayombe or
nile or nubia* or sahara* or sahel or sahrawi or sub-sahara* or
subsahara* or gariep or incomaputo or incomati or juba or
shabelli or komati or kunene or limpopo or okavango or “orange
river” or ruvuma or “lake Victoria” or volta or zambezi or algeria*
This is aisland”
or angol* or “ascension searchorquery
benin*covering 1
or botswan* or “burkina
fas*” or burund*concept
or cameroon*
(Africa)orofcameroun* or “cabo verder” or
a systematic
“cape verd*” or capeverd* or “central african republic*” or chad*
or comor* or congo* orliterature review!or djibout* or egypt* or
“cote d'ivoire”
eritrea* or ethiopia* or gabon* or gambia* or ghan* or guinea*
or guinea-bissau or guinebissau or guinee or “ivory coast*” or
kenya* or lesoth* or liberia* or libya* or madagasc* or malawi*
or mali* or maroc or marocco or morocc* or maurice or
mauritania* or mauriti* or mayott* or mozambiqu* or namibia*
or niger* or nigeria* or “republique centrafricain*” or reunion or
Exercise 3: Concepts and search terms (15 minutes)
For more info: ‘Search strategies’, ‘Systematic search’ in the module ‘Perform a
search and evaluate your search results’ on our webpage with e-learning
modules.
1. Formulate a literature research question
Steps for a
systematic search 5. Execute search
a. Boolean operators
b. Parentheses ()
d. Wildcards * ? # $
● OR: between search terms of the same concept
● AND: between different concepts
● NOT: excluding certain search terms (beware)
(artificial night lighting OR nocturnal light OR nocturnal
illumination) AND (behaviour OR sing OR sleep) AND (great tit
OR parus major)
Phrase searching
Type in Scopus:
Wildcards in Scopus:
*=any amount of characters
?=1 character
Type in Scopus:
Cat
Cat?
Cats
Cat OR Cats
((artificial W/4 night W/4 light*) OR “nocturnal light*” OR
“nocturnal illuminat*”) AND (behaviour OR sing* OR sleep*)
AND (“great tit” OR “parus major”))
Number of Scopus Web of CAB, Psycinfo CAB, Zool. Nat. Sci.
characters Science (EBSCOhost) Rec. (Ovid) Coll., ASFA
(ProQuest)
0 or more * * * * *
(any)
0 or 1 (zero $ # ? ?
or one)
1 (single ? ? ? #
character)
Number of Scopus Web of Science CAB, Psycinfo CAB, Nat. Sci. Coll.,
characters (EBSCOhost) Zool. ASFA
Rec. (ProQuest)
(Ovid)
Note: in most databases phrase searching turns off automatic retrieval of singular, plural and word
variants >> “behaviour change” will not find behaviour changes or behavior change(s)
(not the case in Scopus)
Use for example: “ behav* change?” in Nat Sci Coll. or “behav* change” in Scopus (do not use ?)(also
includes behavioural, behavioral)
Fields (default) Scopus Web of CAB, Psycinfo CAB, Zool. Nat. Sci. Coll.,
and operators Science (EBSCOhost) Rec. (Ovid) ASFA
(ProQuest)
Fields (default) ti, ab, key topic All fields All fields Anywhere,
incl. full text
(artificial night lighting OR artificial light at night OR nocturnal light OR nocturnal illumination)
AND (behaviour OR behavior OR singing OR sleeping) AND (great tit OR parus major)
Zoological record
Elsevier, Public domain, via Wikimedia
On the OVID platform
Commons
(“artificial night light*“ OR “artificial light*” OR “nocturnal (artificial night light* OR artificial light* OR nocturnal light* OR
light*” OR “nocturnal illuminat*”) AND (behavior OR sing* nocturnal illuminat*) AND (behavio?r OR sing* OR sleep*) AND
OR sleep*) AND (“great tit” OR “parus major”) (great tit? OR parus major)
Field searching
Vs
102
Thesaurus
Results: 38
Evaluating - Validation
▪ Precision/specificity:
how much of the records you found is relevant?
▪ Recall/sensitivity:
how much of all relevant records have you found?
Example of a real systematic review
Key concepts:
1. aflatoxin
2. disease
3. africa
Example – concept 1
cited by
cited by
reference
related record
When to follow a thread?
▪ At the start
● to find a few relevant
documents
● to get to know your topic
▪ During search
● to find extra search terms
▪ During or after paper selection
● to validate
Learning goal
▪ You can select the most fitting search strategy for a certain purpose
For info: ‘Following a thread’ in the module ‘Perform a search and evaluate your
search results’ on the Library’s webpage with e-learning modules.
Screening and organizing literature
http://en.wikipedia.org/wiki/Systematic_review
Learning goals
▪ You can use tools for organising, screening and selecting studies in a
systematic review
124
Why organising?
▪ Inclusion/exclusion of papers
▪ Quality assessment of papers
▪ Analysing data from studies
▪ Statistics required
▪ Identify knowledge gaps
https://indelvibe.indelcorp.co.in/
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Report on reasons for exclusion
126
Coding (analysing data from studies)
127
Coding (analysing data from studies)
128
Analysing data from studies
129
Flow scheme
130
Software for organising, screening and selecting studies
▪ EPPI-Reviewer
▪ Covidence
▪ EROS
▪ SUMARI
▪ Distiller-SR
▪ Rayyan
▪ ASReview Lab
▪ EndNote
▪ Mendeley
▪ Zotero
▪ ...
Rayyan
Image Joukje Willemsen (CC BY-NC-ND 4.0)
ASReview Lab
Reference managers
137
Reference managers
Manual
▪ EndNote 20 and EndNote Online
Basic concepts EndNote
▪ Display Fields
● Default fields
● Custom fields
▪ Change Field content
▪ Organise library with Groups
▪ De-duplicate
▪ Find Full text
▪ Search within your library
Display fields – Default fields
Reviewer Topic
Included/excluded Full text ordered
Reason for exclusion …
Country
Via: Edit > Preferences > Display Fields
Change field content
▪ Inclusion/exclusion of publications
▪ Reason for exclusion
● Ineligible population
● Ineligible intervention
●…
▪ Name of reviewer
▪ To organize on topic
● Country/region
● Intervention
● ...
More info:
Display fields and using custom fields for
inclusion/exclusion and name of reviewer
More info:
De-duplication of search results
De-duplication of search results
▪ You can change field settings via Edit > Preferences > Duplicates
Change field settings for de-duplication
Edit >
Preferences
> Duplicates
Duplicate references?
More info:
Demo
Break
Screening and selecting studies
Screening and selecting studies
Review titles in the Unfiled group and assign them to one of the groups you
have created
https://pubrica.com/ 171
Learning goals
▪ You can use EndNote software for creating in-text citations and reference
lists in MS Word
▪ You can create a style for copying references from EndNote to MS Excel
172
Present findings in a scientific paper/report
all invasive plants (Richardson and Rejmánek, 2011), whereas others are commercially important crops
(Kull et al., 2011). Some species are both invasive and commercially important, like A. dealbata.
Integration with MS Word
Style for in-text citations and reference lists
175
Styles
177
Present findings in an MS Excel file
Create your style for copying references to MS excel
More info:
Demo
Optional exercise 7: Create your style (30 min)
Choose a style for copying references to MS Word and create some in-text
citations and a reference list according to this style
and/or
▪ EndNote
See For students on library website
Reaching your goal
From: www.SYRCLE.nl
Questions?