Seminar Topic:

control and Quality chemo-metrics

Submitted To:
Department of PG studies in Chemistry,
Govt. Science College (Autonomous), Hassan

Submitted By:
RAJESH B L
I MSc. I Sem. Chemistry
GOVT. SCIENCE COLLEGE(AUTONOMOUS), HASSAN

Under the Supervision of:

MANJUNATH
Guest lecturer
Department of PG Studies in Chemistry
Govt. Science College (Autonomous), Hassan

Date of Submission:
27-12-2023
CONTENTS:

• INTRODUCTION
• QUALITY CONTROL
• CHEMO-METRICS
• CONTROL CHART
• COLLABORATIVE TEST
• MULTI-VARIATION STATICS
• CONCLUSION
• REFERENCE
INTRODUCTION:
Quality control deals with the system which accepts or rejects any activities or parameter which
affects the quality of product and thus prevent quality deficiency. Quality control confined to only
laboratory operation but must be involved in all decisions, concerning with the quality of the product .
Chemometrics, first introduced by the Swedish scientist Svante wold in 1971, is simply the application
of mathematical and statistical techniques to retrieve more information from the chromatographic data

Quality control:
Quality control is the process of ensuring that a product or service meets a certain level of quality. It
involves establishing quality standards and procedures, monitoring performance, identifying defects, and
implementing corrective measures.

Chemo-metrics:
Chemo-metrics is a subfield of analytical chemistry that involves the application of mathematical and
statistical methods to chemical data. It is used to analyze complex data sets, such as those generated by
chromatography, spectroscopy, and other analytical techniques.

Control charts:
Control charts are a statistical tool used in quality control to monitor a process and determine
whether it is stable and predictable. They are graphs that plot process data over time and include upper
and lower control limits to show when a process is operating within acceptable limits. If data points fall
outside the control limits, it indicates that the process is not stable and requires corrective action.

Collaborative testing:
Collaborative testing is a quality control technique that involves multiple laboratories or testers
working together to evaluate the performance of a product or test method. This approach can help identify
sources of variability and improve the accuracy and precision of results.

Multivariate statistics:
Multivariate statistics is a branch of statistics that deals with the analysis of data sets with multiple
variables. It is used to identify relationships between variables and to make predictions based on those
relationships. In quality control, multivariate statistics can be used to analyze data from multiple sources
and to identify patterns or trends that may indicate problems with a process or product .
Quality control:
Quality control is a process that is used to ensure that a product or service meets a certain level of
quality or standard. This process involves monitoring and evaluating the product or service at various
stages of production to identify any defects or inconsistencies, and then taking corrective actions to
address these issues.
The goal of quality control is to ensure that the final product or service meets the requirements and
expectations of customers, and that it is safe, reliable, and efficient. Quality control is an important aspect
of many industries, including manufacturing, healthcare, construction, and software development.
Some common methods used in quality control include statistical process control, inspections and
audits, testing and analysis, and process improvement. Quality control is often a collaborative effort
between different departments or teams within an organization, and it requires ongoing communication,
training, and monitoring to be effective.

Chemo-metrics:
Chemometrics is the application of statistical and mathematical methods to analyze chemical data. It
is a multidisciplinary field that combines chemistry, mathematics, statistics, and computer science to
extract useful information from chemical measurements.

Chemometric methods are used in a Wide range of applications, including analytical chemistry,
pharmaceuticals, food and beverage production, environmental monitoring, and material science. Some
common chemometric methods include:

1. Multivariate statistical analysis: This involves the analysis of data sets with
multiple variables. It is used to identify patterns and relationships between variables,
and to identify outliers and Data errors

2. Calibration and prediction: This Involves the development of models to predict the behavior
of a chemical system based on measured data. It is used to optimize chemical processes and
to predict the performance of new materials and products.

3. Pattern recognition: This involves the identification of patterns in large data sets. It is used
to classify samples into different groups, and to identify outliers and anomalies.

4. Experimental design: This involves the systematic planning and execution of experiments to
maximize the amount of information obtained from a given set of resources.
 Overall, chemometrics provides a powerful set of tools for analyzing chemical data and extracting
Useful information from complex systems.

Control charts:
Control charts are a statistical tool used in quality control to monitor a process and determine
whether it is in a state of statistical control. They are commonly used in manufacturing, healthcare, and
other industries where the quality of a process or product is critical.

The basic idea behind control charts is to plot a series of data points over time and look for patterns
or trends that indicate the process is out of control. The chart includes two lines: a central line that
represents the average or expected value of the process, and two control limits that define the range of
values that the process should fall within. If the data points fall within the control limits, the process is
considered to be in control and operating as expected.

If the data points fall outside the control limits or show a pattern or trend that is not random, this
suggests that the process is out of control and needs to be investigated and corrected.

Control charts can be used for a variety of quality control applications, including monitoring the
performance of manufacturing processes, tracking patient outcomes in healthcare settings, and evaluating
the accuracy of laboratory tests. They are a useful tool for identifying problems early on and making
corrections before they have a significant impact on the quality of a product or service.

Collaborative testing:
Collaborative testing is a testing approach that involves multiple individuals working together to test
a product or system. The goal of collaborative testing is to improve the quality of the product or

system by leveraging the diverse knowledge, skills, and perspectives of the team members.
In collaborative testing, team members may work together in various ways, such as:

1. Pair testing: Two team members work together on testing a particular feature or area of the
system. One person acts as the driver, while the other person Observes and provides
feedback.

2. Team testing: A group of team members work together to test the system, sharing their ideas,
findings, and feedback.

3. Mob testing: The entire team works together on testing the system, with one person acting
as the driver at a time while the rest of the team observes and provides feedback.
 Collaborative testing can be used in different stages of the software development lifecycle, including
requirements gathering, design, development, and testing. It can help identify defects earlier in the

process, reduce the overall testing time, and improve the quality of the product by bringing in
diverse perspectives and knowledge.

Effective communication, mutual respect, and clear expectations are important factors for successful
collaborative testing. Team members should be encouraged to share their ideas and feedback

openly and constructively, and to work towards a common goal of improving the quality of the
product or system.

MULTIVARIATION STATISTICS:
Multi-variation statistics is a statistical analysis technique used to analyze data that involves more

than one independent variable. It is also referred to as multivariate analysis or multiple regression
analysis.

In multi-variation statistics, the goal is to identify the relationship between two or more
independent variables and a dependent variable. The analysis involves determining the effect of

each independent variable on the dependent variable while holding all other variables constant. This
allows for a more
Comprehensive understanding of the relationships among the variables in the data set.

Some common techniques used in multi-variation statistics include multiple regression analysis,

factor analysis, and cluster analysis. These techniques can be used to identify patterns and relationships
among variables, as well as to develop predictive models.

Multi-variation statistics is used in a variety of fields, including social sciences, marketing, finance,
and healthcare. It can be used to analyze consumer behavior, market trends, financial data, and
clinical outcomes, among other things. By understanding the relationships among multiple variables,
researchers and practitioners can make more informed decisions and develop more effective

strategies.
CONCLUSION:

Quality control plays a crucial role in ensuring that businesses deliver high-quality products and
services, meeting customer expectations and regulatory requirements. Quality control means how a
company measures product quality improves it if need be. Quality control ca be done in the many ways,
from testing products, reviewing manufacturing processes, and creating benchmarks. This is all done to
monitor significant variations in a product.

Chemometrics is the science of extracting information from chemical systems by data-driven

means. Chemometrics is inherently interdisciplinary, using methods frequently employed in core data-
analytic disciplines such as multivariate statistics, applied mathematics, and computer science, in this order
to address problems in chemistry, biochemistry, medicine, biology and chemical engineering. In this way, it
mirrors other interdisciplinary fields, such as psychometrics and econometrics.
REFERENCE:

• Modern Analytical Chemistry - David Harvey and Mc Graw Hill

• Fundamentals of Analytical chemistry – D. A. Skoog, D.M. West, Holler and Crouch