Universal Medical and
Business College
Assessment of Cardiovascular
system
By: Hailye Mamo (BSc, MSc)
July, 2024
Addis Ababa, Ethiopia.
Learning Objectives
On completion of this chapter, learner will be able to:
Explain the anatomy and physiology of the cardiovascular
system
Describe the components of cardiovascular system
Explain the assessment of cardiovascular system
2
Questions???
• What is cardiovascular system?
• What are the components of CVS?
• Functions of the heart?
• Function of blood?
• How can we assess the CVS?
• Disease that you know from the CVS previously?
3
Anatomy and physiology overview of CVS
Components of cardiovascular system
Heart- circulates blood through vessels.
Blood vessels
◦ Arteries- away from the heart
◦ Veins- towards the heart
◦ Capillaries- a connecting network between artery &
veins.
Blood- transport medium of the body.
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a) The Blood
⚫Is classified as a connective tissue, since nearly half of it is
made up of cells.
⚫However, it differ from other connective tissues in that its
cells are not fixed in position, instead they move freely in
the liquid portion of the blood, the plasma.
5
Composition of Blood
⚫Plasma
◦ Liquid portion of the blood
◦ The plasma itself is 90% water.
◦ Many different substances dissolved or suspended in the
water, make up the other 10%
⚫Formed elements
◦ The cells and fragments of cells
Erythrocytes, leukocytes and platelets
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Functions of the blood
Transportation
Oxygen
Foods and other needed substances
Waste products
Hormones
Regulation
PH
Body temperature
Protection
Against pathogens
Blood loss
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b)The Blood Vessels:
⚫Together with the four chambers of the heart, B/d vessels
flow blood throughout the body.
Functional classification
Taking blood to the tissues and back to heart
Arteries
Veins
Capillaries
8
Structure of blood vessels
• Three coats or layers are found in both arteries &
veins except the capillaries
1. Tunica externa:- The outermost layer of a blood
vessel.
2. Tunica media: The middle layer of a blood
vessel
3. Tunica interna /intima: The innermost layer of a
blood vessel
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Location of Heart
♥ Posterior to sternum
♥ Medial to lungs
♥ Anterior to vertebral column
♥ Base lies beneath 2nd rib
♥ Apex at 5th inter-costal
space
♥ Lies upon diaphragm
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Coverings of the heart
Pericardium-loose fitting, double layered sac.
Visceral pericardium-serous membrane that is on the
surface of the heart muscle
Parietal pericardium- outer layer of sac; secretes
pericardial fluid
Pericardial fluid- (Serous fluid)-fluid that is between
the parietal and visceral pericardium which prevents
friction as the heart beats.
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Layers of heart tissue
1. Epicardium
2. Myocardium
3. Endocardium
15
1. Endocardium
▸ Inner lining
▸ Smooth surface that permits blood to move easily
through the heart without agglutination.
▸ Continuous with lining of blood vessels
16
2. Myocardium
Middle layer made of cardiac muscle
Forms the bulk of the heart wall
Contains the septum- a thick muscular wall that
completely separates the blood in the right side of the
heart from the blood in the left side.
17
3. Epicardium
Protective, outer layer of the heart wall same as the
visceral pericardium
The coronary blood vessels that nourish the heart wall
are located here
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Chambers of Heart
1. Right Atrium 2. Right Ventricle
Thinner wall than Thicker wall than atria
ventricles Comprises most of
Receives deoxygenated anterior surface of heart
blood from vena cava Circulates deoxygenated
Passes blood through blood to lungs through
tricuspid valve into the pulmonic valve into
right ventricle pulmonary trunk
By:Hailye. M (BSc, MSc) 7/21/2024 21
Chambers of Heart cont’d…
3. Left Atrium 4. Left Ventricle
Receives blood from left
Receives freshly
atrium
oxygenated blood from
pulmonary vein Thickest myocardial wall
Passes blood to left Forms apex of heart
ventricle through Sends blood to systemic
mitral valve circulation via aorta
Aortic valve:-b/n the Lt
ventricle & aorta
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Heart Valves
Function: prevent blood from flowing backwards
Responds to changes in pressure
Two types of valves in the heart:
1. Atrio-ventricular valves (AV)
2. Semi-lunar valves
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A) Atrioventricular valves
► Valve cusps are connected to papillary muscles
► Chordae tendineae tiny collagen cords that anchor cusps
of valve to papillary muscles
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A) Atrioventricular valves cont’d…
Left AV valve (Mitral/bicuspid)
Contains 2 cusps
Right AV valve (Tricuspid)
Contains 3 cusps
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B) Semilunar valves
Located at exit of ventricles, originate from endothelial
lining of veins
Heart contains two semilunar valves
1. Pulmonic
2. Aortic (Frequently damaged by HTN)
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Blood circulation
▸ The blood passes through the tricuspid valve into the
right ventricle, which then pumps the blood through the
pulmonic valve into the pulmonary circulation.
▸ After gas exchange in the lungs, oxygenated blood
returns to the left atrium, passes through the mitral
valve, enters the left ventricle, passes through the
aortic valve, and finally enters the aorta.
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Coronary circulation
Blood in the heart chambers does not nourish the
myocardium
The heart has its own nourishing circulatory system
The left and right coronary arteries and their branches
supply arterial blood to the heart.
These arteries originate from the aorta just above the
aortic valve leaflets.
33
Coronary circulation cont’d…
▸ The right side of the heart is supplied by the Right
coronary artery, which progresses around to the
bottom or inferior wall of the heart.
▸ The posterior wall of the heart receives its blood supply
by an additional branch from the right coronary artery
called the Posterior descending artery.
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35
NB:
▸ The coronary arteries are perfused during diastole.
▸ An increase in heart rate shortens diastole and can
decrease myocardial perfusion.
▸ Patients, particularly those with coronary artery
disease (CAD), can develop myocardial ischemia
(inadequate oxygen supply) when the heart rate
accelerates.
36
Coronary veins
Transport deoxygenated blood to coronary sinus
Coronary Sinus drains into right atrium.
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The heart beat
Each heartbeat is called a cardiac cycle.
When the hart beats, the two atria contract together ; then
the two ventricles ;then the whole heart relaxes.
Systole is the contraction of heart chambers; diastole is their
relaxation (heart fill with blood).
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Intrinsic control of heart beat
The Sinoatrial (SA) node, or pacemaker ,initiates the hear beat
and causes the atria to contract.
The Atrioventricular (AV) node conveys the stimulus and
initiates contraction of the ventricles .
The signals for the ventricles to contract travels from the AV
node through the atrioventricular bundle to the smaller
Purkinje fiber.
The SA node in anormal resting adult heart has an inherent firing
rate of 60 to 100 impulses per minute.
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Extrinsic control of heartbeat
A cardiac control center in the medulla oblongata speeds
up or slows down the heart beat by ways of the autonomic
nervous system branches : parasympathetic system
(slows heart rate) and sympathetic system(increases
heart rate).
Hormones epinephrine and norepinephrine from the
adrenal medulla also stimulate faster heart rate.
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QUESTION:
What effect will each of the following have on heart rate?
A) Anxiety
B) Fever
C) Hypothyroidism;
D) Caffeine
E) Athletic conditioning.
F) Shock and hemorrhage
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Heart sounds
The normal heart sounds, S1 and S2, are produced
primarily by the closing of the heart valves.
The time between S1 and S2 corresponds to systole.
This is normally shorter than the time between S2
and S1 (diastole).
As the heart rate increases diastole shortens.
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S1— First heart sound
Closure of the mitral and tricuspid valves
Vibration of the myocardial wall also may
contribute to this sound
It is heard best at the apex of the heart (apical
area)
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S2— Second heart sound
Closing of the aortic and pulmonic valves produces the
second heart sound (S2).
These two valves close almost simultaneously,
but the pulmonic valve usually lags slightly
behind.
Therefore, under certain circumstances, the two
components of the second sound may be heard
separately (split S2)
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Gallop Sounds (S3)
oProduced by rapid ventricular filling and occurs in
early-mid diastole
o It represents a normal finding in children and young
adults
4th Heart Sound, S4
oThis is an atrial sound, occurring just before S1.
oIt is always abnormal
oIt represents atrial contraction against a stiffened
ventricle e.g. Due to aortic stenosis or hypertensive
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Friction Rub
• A harsh, grating sound that can be heard in both
systole and diastole
• It is caused by abrasion of the pericardial
surfaces during the cardiac cycle
• Distinguish it from murmurs that may be heard in
both systole and diastole.
• Can be heard best using the diaphragm of the
stethoscope, with the patient sitting up and
leaning forward. 48
Cardiac output
Cardiac output
Amount of blood ejected from the left ventricle over 1
minute
In resting adult it is about 5 L per minute
Is computed by multiplying the stroke volume by
the heart rate
Stroke volume
◦ Amount of blood that is ejected with each heartbeat
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Rest and Digest
1. If a person’s heart rate is 72 beats per minute (bpm), and
the heart ejects 70ml per each beats. what is the cardiac
output?
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Stroke volume
Is the amount of blood ejected per heart beat
Is primarily determined by three factors:
Preload,
Afterload, and
Contractility
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The degree of stretch of the cardiac muscle fibers at the
end of diastole.
As the volume of blood returning to the heart
increases, muscle fiber stretch also increases
(increased preload),
Is decreased by a reduction in the volume of blood
returning to the ventricles.
52
The amount of resistance to ejection of blood from the
ventricle.
Is increased by arterial vasoconstriction
The resistance of the systemic BP to left ventricular
ejection is called systemic vascular resistance.
The resistance of the pulmonary BP to right ventricular
ejection is called pulmonary vascular resistance
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Is a term used to denote the force generated by
the contracting myocardium under any given
condition.
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Assessing Patient’s CV Status
• What are the
common signs
& symptoms of
cardiovascular
disorders ?
By:Hailye. M (BSc, MSc)
7/21/2024 57
Assessing Patient’s CV Status
1. Chest pain: in cardiovascular system the commonest cause for
chest pain are:
Myocardial infraction, angina ,acute pericardial disease
ACS (acute coronary syndrome)
Pain similar to angina ; may be more intense
Often occurs at rest
Not relieved by rest; requires analgesic
Pericarditis
Described as sharp, stabbing, shooting
Aggravated by movement
Tend to be constant
Relieved by sitting up, leaning forward, shallow breathing
58
Assessing Patient’s CV Status…
2). Dyspnea
Subjective sensation of being unable to breath
Usually caused by congestion from Left Ventricular
Failure (LVF)
Types:
Dyspnea on exertion (DOE)
Orthopnea : inability to breathe while lying flat
Paroxysmal nocturnal dyspnea (PND): night time
episodes of SOB due to lying flat which increases venous
return (preload).
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Assessing Patient’s CV Status cont’d…
3). Fatigue / Weakness
▸ Symptom of decreased forward CO
▸ Unusual fatigue, sometimes referred to as vital
exhaustion (an early warning symptom of ACS, HF,
or valvular heart disease, characterized by feeling
unusually tired or fatigued, irritable, and dejected)
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Assessing Patient’s CV Status cont’d…
4). Fluid retention
Fluid accumulation in tissues
Peripheral edema, weight gain, abdominal
distention due to enlarged spleen and liver or
ascites (HF)
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Assessing Patient’s CV Status cont’d…
5). Syncope/Presyncope
◦ Temporary loss of consciousness,
lightheadedness, dizziness
◦ Cardiac cause most commonly result of inadequate
cardiac output from arrhythmias
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Assessing Patient’s CV Status cont’d…
6). Palpitations
◦ Awareness of heart beat with sudden changes in rate,
rhythm, increased stroke volume.
◦ Associated with : tachycardias, bradycardias, atrial
fibrillation, aortic and mitral regurgitation, signs of
heart failure.
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Assessing Patient’s CV Status cont’d…
7. Other symptoms
◦ GI
Nausea, anorexia, vomiting.
Indigestion or flu like symptoms may be sole s/s of MI.
◦ Extremity pain
Intermittent claudication indicative of Peripheral Vascular
Disease (PVD) due to decreased blood flow to muscles
during time of increased demand.
Ischemia from PVD
6
4
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Assessing Patient’s CV Status cont’d…
7). Other symptoms…
◦ Decreased urine output
Indicative of heart failure and hypovolemia
Look for concomitant weight gain due to CHF
◦ Nocturia
Sign of heart failure
Caused by increased preload to heart
6
5
Assessing Patient’s CV Status cont’d…
Risk Factors
◦ Non-modifiable
Age
Sex
Family history
Race
◦ Modifiable
Cigarette smoking
Hypertension
Hyperlipidemia
Physical inactivity
Diabetes
Stress
Obesity
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Assessing Patient’s CV Status cont’d…
Social History
◦ Alcohol intake
◦ Dietary pattern: caffeine , salt intake
◦ Cocaine
◦ Educational level
Medication History
◦ Prescribed drugs
◦ Over-the-counter drugs(OTC)
67
Cardiovascular physical examination
▸ General Appearance
▸ Vital Signs
▸ Jugular Veins
▸ Heart
▸ Peripheral Pulses
68
VITAL SIGNS
- Both arms
- BP
- Hypertension, hypotension ,
orthostatic hypotension
- Pulse Pressure
= Heart Rate =Tachycardia, Bradycardia
• Regular, Regularly
• Rhythm
irregular, irregularly
irregular
+ Respirations + Tachypnea/Bradypnea
• Temperature • Fever 7/21/2024 69
Inspection
Jaundice
◦ Best seen in sclera
◦ Sign of right – side heart failure (from hepatic
impairment) or chronic hemolysis from
prosthetic heart value.
Pallor
◦ Indicates anemia
◦ Inspect palm of hands
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Jugular venous pressure (JVD)
Recall that jugular veins reflect right atrial pressure
Steps for JV examination
Raise the head of the bed or examining table to a 30- to a 45-
degree angle.
Turn the patient’s head gently to the left
Identify the top most point of the flickering venous
pulsations
Place a centimeter ruler upright on the sternal angle
Place a card or tongue blade horizontally from the top of the
JVP to the ruler, making a right angle
Measure the distance above the sternal angle in
centimeters: a 3- to 4-centimeter elevation is normal
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assessment of central venous pressure.
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Top line – level of the higest visible point
⚫
of distention
⚫ Bottom line – level of the sternal angle
Measure: the vertical distance between
⚫
the sternal angle and the highest level of
jugular distention
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Cyanosis
◦ Central cyanosis
low oxygen saturation of arterial blood.
Noted on tongue, buccal mucosa and lips
Indicative of cardiopulmonary disease (heart failure or
pulmonary edema).
◦ Peripheral cyanosis
Reduced blood flow through extremities due to
vasoconstriction
Noted on distal aspects of extremities, tip of nose and
earlobes
Due to cold exposure or obstructive peripheral
vascular disease 74
75
Palpation
◦ Edema
Usually not detectable until interstitial fluid
volume is 30% above normal
Bilateral edema
Progression from ankles , legs, thighs, genitalia
and abdomen, presacral for bed rest.
Indicative of heart failure or bilateral venous
insufficiency (unilateral seen in venous
thrombosis and lymphatic blockage of
extremity)
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Palpation (continued)
Palpation of the chest, including the following
◦ Precordium at the right and left second
intercostal spaces
◦ Left third intercostal space
◦ Left fourth intercostal space
◦ Left fifth intercostal space at the midclavicular line
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Landmarks for palpation of the
chest.
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PALPATION(continued)
Impulses - finger pads
Thrills (vibrations palpated secondary to a
murmur—turbulent blood flow through a heart valve) -
Bony part of hand, ball of hand.
Apical impulse (normally 5th ICS and medial to mid-
clavicular line)
Point of maximum impulse (PMI)
Left lateral position (heart closer to chest well)
apical impulse more easily palpable
79
Palpation(continued)…
Major Arteries:
Temporal, Carotid, Brachial, Radial, Femoral, Popliteal, Posterior
Tibial, Dorsalis Pedis. Palpate for the pulse on each side.
comparing pulse volume and symmetry.
Do not palpate both carotid arteries at the same time or press
too firmly.
If you do the patient may faint or become Bradycardia.
Radial artery is commonly used to assess heart rate and
rhythm.
Compare the left radial pulse with that of the right.
Lack of symmetry may indicate impaired circulation
Localized obstruction
Abnormally positioned artery.
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PERCUSSION
Percussion of the chest for cardiac border
81
AUSCULTATION
◦ Blood pressure
Overall reflection of Left Ventricular function
Systolic represents force of contraction
Diastolic represents vascular resistance
(afterload)
Pulse pressure – difference between systolic
and diastolic
82
HEART BORDERS
◦ Specific areas for examination
Aortic area: 2nd ICS, RSB
Pulmonic area: 2nd ICS, LSB
Tricuspid area: 4th ICS, LSB
Mitral or Apical area: 5th ICS,
MCL
83
HEART SOUNDS
◦ Closure of valves
S1
irst heart sound ―‘’lub‘’; closure of AV
valves heard loudest at mitral and
tricuspid areas; usually lower pitch
than S2
S2
second heart sound ― ‘’dub‘’; closure
of semilunar valves; heard best at
aortic and pulmonic areas
84
HEART SOUNDS…
S3
Ventricular gallop
Heard in early diastole, just after S2
Due to rapid, early ventricular filling
Indicates loss of ventricular compliance, diastolic
overloading, heart failure
Heard best : bell, mitral area if produced by left heart
; along sternal borders if produced by right heart
85
MURMUR
Turbulent blood flow
Often imply significant disease of heart valves, great
vessels, or septal defects
Timing of murmurs is a must!
Systolic murmurs occur between S1 & S2
Diastolic murmurs occur between S2 & S1
Grade 1 – 6 identifies intensity of murmur
86
Extra cardiac sounds
◦ Pericardial Friction Rubs
Caused by inflammation of pericardium.
Rough, scratchy, squeaky sound ―like two pieces
of leather rubbing against each other.
Best heard with patient leaning forward, holding
breath in full expiration.
87
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Diagnostic studies of cardiovascular
system
Cardiac Enzymes Test
⚫Tests performed on samples of blood obtained by vein
puncture to determine the presence of damage to the
myocardial muscle.
⚫When heart cells are damaged or die, they rupture and
release enzymes into the bloodstream.
⚫Levels of these enzymes rise in the serum as a
result.
89
Diagnostic studies of cardiovascular
system ,,,
⚫Because different enzymes move into the blood at
varying periods after Myocardial Infraction (MI),
enzyme levels should be tested in relation to the time
of onset of chest discomfort or other symptoms.
90
Diagnostic studies of cardiovascular
system,,,
⚫A common cardiac enzyme test is creatine kinase
(CK), also referred to as creatine phosphokinase
(CPK).
⚫Lactic dehydrogenase and its isoenzymes also are
analyzed in patients who have delayed seeking
medical attention, because these blood levels rise and
peak in 2 to 3 days, much later than CK levels
91
Diagnostic studies of cardiovascular
system,,,
⚫Myoglobin, an early marker of MI, is a heme
protein with a small molecular weight.
⚫This allows it to be rapidly released from damaged
myocardial tissue and accounts for its early rise, within 1
to 3 hours after the onset of an acute MI.
⚫Myoglobin is not used alone to diagnose MI, because
elevations can also occur in patients with renal or
musculoskeletal disease.
92
Diagnostic studies of cardiovascular
system,,,
⚫Troponin I is a contractile protein found only in
cardiac muscle.
⚫ After myocardial injury, elevated serum troponin I
concentrations can be detected within 3 to 4 hours; they
peak in 4 to 24 hours and remain elevated for 1 to 3
weeks.
93
Diagnostic studies of cardiovascular
system,,,
Angiography
⚫X-ray visualization of internal anatomy of heart and
blood vessels after introducing a radiopaque substance
(contrast medium).
This test Promotes imaging of internal structures that
are otherwise difficult to see on X-ray film and used to
assess blood clot formation, to assess peripheral
vascular disease (PVD).
94
Diagnostic studies of cardiovascular
system,,,
Echocardiography
⚫It is an ultrasound test that records the motion of the
heart structures, including the valves, as well as the heart
size, shape, and position.
⚫Useful in evaluating structural and functional changes
in a variety of heart disorders.
⚫ No preparation is required for a cardiac ultrasound.
95
Diagnostic studies of cardiovascular
system,,,
This test transmits ultrasonic sound waves into the
heart so that the returned echoes can be recorded on
videotape as audio and visual information.
• An ElectroCardioGram (ECG)is recorded at the same
time for comparison purposes.
Abnormalities that may be seen on the
echocardiogram include heart enlargement, valvular
abnormalities, thickened cardiac walls or septum, and
pericardial effusion.
96
Diagnostic studies of cardiovascular
system,,,
Electrocardiogram (EKG, ECG)
⚫Graphic record of the electrical action of the heart as
reflected from various angles to the surface of the skin
⚫The ECG shows abnormalities related to
conduction, rate, rhythm, heart chamber
enlargement, myocardial ischemia, myocardial
infarction, and electrolyte imbalances.
97
Diagnostic studies of cardiovascular
system,,,
⚫ Abnormalities in cardiac function can be detected and
the area of abnormality pinpointed with the aid of the
different views on the ECG.
⚫To obtain an ECG, electrodes are placed on the skin to
transmit electrical impulses to the ECG machine for
recording.
⚫The electrical impulses from the heart appear as waves on
graph paper.
98
99
Diagnostic studies of cardiovascular
system,,,
Cardiac catheterization
⚫Invasive diagnostic procedure in which a catheter is
introduced into a large vein or artery, usually of an arm or
a leg, and is then threaded through the circulatory system
to the heart.
⚫Used to obtain detailed information about the
structure and function of the heart chambers, valves,
and the great vessels.
100
Diagnostic studies of cardiovascular
system,,,
⚫Measures pressures in the heart chambers, great blood
vessels, and coronary arteries and provides
information on cardiac output and oxygen saturation.
⚫Fluoroscopy is used, and dye can be injected once the
catheter is in place to visualize the heart chambers and
vessels.
⚫This procedure is often done before heart surgery.
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